Publication
NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker.
Authors not recorded
Mod Pathol2020PMID 32327700stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerRound Cell Sarcoma with EWSR1-non-ETS Fusioncivic_curation1.00
- geneNFATC2civic_curation1.00
- variantNFATC2 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 32327700
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NFATC2 Fusion1 | ||||||||
| (diagnostic) | Round Cell Sarcoma with EWSR1-non-ETS Fusion | Diagnostic | C | Supports Positive | 2 | accepted | EID12692This case series presented 7 NFATC2-rearranged sarcomas, including 4 EWSR1::NFATC2 and 3 FUS::NFATC2 cases, and developed an ACAN-encoding aggrecan immunohistochemistry as a diagnostic tool for these … (full text at CIViC) PMID 32327700 · Perret et al., 2020 · Open in CIViC | civic |