Clear Cell Adenocarcinoma — Genomics

Clear Cell Adenocarcinoma — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

12 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Clear Cell Renal Cell Carcinoma (DFCI, Science 2019) ccrcc_dfci_2019DFCI

35 cases with simple somatic mutation data · 35 cases total · 2026-01-05 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.

Kidney Renal Clear Cell Carcinoma TCGA-KIRCTCGA

536 cases with simple somatic mutation data · 537 cases total · Data Release 46.0 · mapped to Clear Cell Renal Cell Carcinoma ONTOLOGY_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	463	536	86.4%	gdc
2	PBRM1	Ssm	456	536	85.1%	gdc
3	BAP1	Ssm	451	536	84.1%	gdc
6	GLB1	Ssm	450	536	84%	gdc
4	PLXNB1	Ssm	450	536	84%	gdc
5	COL7A1	Ssm	450	536	84%	gdc
19	FBXW12	Ssm	449	536	83.8%	gdc
7	TREX1	Ssm	449	536	83.8%	gdc
8	CDC25A	Ssm	449	536	83.8%	gdc
9	CELSR3	Ssm	449	536	83.8%	gdc
10	PRKAR2A	Ssm	449	536	83.8%	gdc
11	UQCRC1	Ssm	449	536	83.8%	gdc
12	PTH1R	Ssm	449	536	83.8%	gdc
13	SLC26A6	Ssm	449	536	83.8%	gdc
14	SETD2	Ssm	449	536	83.8%	gdc
15	UCN2	Ssm	449	536	83.8%	gdc
16	SHISA5	Ssm	449	536	83.8%	gdc
17	CCDC51	Ssm	449	536	83.8%	gdc
18	PFKFB4	Ssm	449	536	83.8%	gdc
20	SCN5A	Ssm	449	536	83.8%	gdc
21	NCKIPSD	Ssm	449	536	83.8%	gdc
22	HHATL	Ssm	449	536	83.8%	gdc
23	VIPR1	Ssm	449	536	83.8%	gdc
24	ATRIP	Ssm	449	536	83.8%	gdc
25	TMA7	Ssm	449	536	83.8%	gdc
26	IP6K2	Ssm	449	536	83.8%	gdc
27	TMEM89	Ssm	449	536	83.8%	gdc
30	DCAF1	Ssm	448	536	83.6%	gdc
29	LAMB2	Ssm	448	536	83.6%	gdc
28	SLC25A20	Ssm	448	536	83.6%	gdc

Data updated 22 days agoSource updated Data Release 46.0

Kidney Renal Clear Cell Carcinoma (BGI, Nat Genet 2012) kirc_bgiBGI

98 cases with simple somatic mutation data · 98 cases total · 2026-01-07 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	25	98	25.5%	cbioportal
2	KDM5C	Ssm	9	98	9.2%	cbioportal
4	LRP1B	Ssm	7	98	7.1%	cbioportal
5	SYNE2	Ssm	7	98	7.1%	cbioportal
3	BAP1	Ssm	7	98	7.1%	cbioportal
6	TP53	Ssm	6	98	6.1%	cbioportal
8	AKAP13	Ssm	5	98	5.1%	cbioportal
9	CSMD3	Ssm	5	98	5.1%	cbioportal
10	RYR1	Ssm	5	98	5.1%	cbioportal
11	SPTBN4	Ssm	5	98	5.1%	cbioportal
7	AHNAK	Ssm	5	98	5.1%	cbioportal
13	FAM111B	Ssm	4	98	4.1%	cbioportal
14	NAV3	Ssm	4	98	4.1%	cbioportal
15	SETD2	Ssm	4	98	4.1%	cbioportal
16	ZNF804A	Ssm	4	98	4.1%	cbioportal
12	CARD11	Ssm	4	98	4.1%	cbioportal
25	TSC1	Ssm	3	98	3.1%	cbioportal
24	SHANK1	Ssm	3	98	3.1%	cbioportal
23	PZP	Ssm	3	98	3.1%	cbioportal
22	MTOR	Ssm	3	98	3.1%	cbioportal
21	LRRK2	Ssm	3	98	3.1%	cbioportal
20	KMT2C	Ssm	3	98	3.1%	cbioportal
19	FMN2	Ssm	3	98	3.1%	cbioportal
18	CUL7	Ssm	3	98	3.1%	cbioportal
17	ATRNL1	Ssm	3	98	3.1%	cbioportal
27	AFDN	Ssm	2	98	2%	cbioportal
26	ADCY9	Ssm	2	98	2%	cbioportal
30	BTRC	Ssm	2	98	2%	cbioportal
29	APC	Ssm	2	98	2%	cbioportal
28	AGXT	Ssm	2	98	2%	cbioportal

Data updated 22 days agoSource updated 2026-01-07

Kidney Renal Clear Cell Carcinoma (IRC, Nat Genet 2014) ccrcc_irc_2014IRC

78 cases with simple somatic mutation data · 79 cases total · 2026-01-05 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	62	78	79.5%	cbioportal
2	PBRM1	Ssm	29	78	37.2%	cbioportal
3	SETD2	Ssm	21	78	26.9%	cbioportal
4	BAP1	Ssm	19	78	24.4%	cbioportal
5	DOP1A	Ssm	17	78	21.8%	cbioportal
6	UGT2A1	Ssm	15	78	19.2%	cbioportal
7	DAPK1	Ssm	13	78	16.7%	cbioportal
8	ANO5	Ssm	12	78	15.4%	cbioportal
9	CENPF	Ssm	12	78	15.4%	cbioportal
10	MYH8	Ssm	12	78	15.4%	cbioportal
11	DUSP19	Ssm	11	78	14.1%	cbioportal
12	EDC4	Ssm	11	78	14.1%	cbioportal
13	GLTPD2	Ssm	11	78	14.1%	cbioportal
14	ITGB3	Ssm	11	78	14.1%	cbioportal
15	MUC16	Ssm	11	78	14.1%	cbioportal
16	OR2A14	Ssm	11	78	14.1%	cbioportal
17	PPP6R1	Ssm	11	78	14.1%	cbioportal
18	UNC80	Ssm	11	78	14.1%	cbioportal
28	EXT1	Ssm	10	78	12.8%	cbioportal
19	ATP11B	Ssm	10	78	12.8%	cbioportal
20	ATXN1	Ssm	10	78	12.8%	cbioportal
21	BCAS2	Ssm	10	78	12.8%	cbioportal
22	C11ORF68	Ssm	10	78	12.8%	cbioportal
23	CCR6	Ssm	10	78	12.8%	cbioportal
24	CLCN2	Ssm	10	78	12.8%	cbioportal
25	CYP4F3	Ssm	10	78	12.8%	cbioportal
26	DDX52	Ssm	10	78	12.8%	cbioportal
27	EIF4G2	Ssm	10	78	12.8%	cbioportal
29	FCAMR	Ssm	10	78	12.8%	cbioportal
30	GARRE1	Ssm	10	78	12.8%	cbioportal

Data updated 22 days agoSource updated 2026-01-05

Kidney Renal Clear Cell Carcinoma (TCGA, Firehose Legacy) kirc_tcgaTCGA

451 cases with simple somatic mutation data · 538 cases total · 2026-01-07 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	225	451	49.9%	cbioportal
2	PBRM1	Ssm	133	451	29.5%	cbioportal
3	MUC4	Ssm	77	451	17.1%	cbioportal
4	TTN	Ssm	71	451	15.7%	cbioportal
5	MUC16	Ssm	58	451	12.9%	cbioportal
6	SETD2	Ssm	51	451	11.3%	cbioportal
7	BAP1	Ssm	40	451	8.9%	cbioportal
8	MTOR	Ssm	32	451	7.1%	cbioportal
9	FBN2	Ssm	30	451	6.7%	cbioportal
10	XIRP2	Ssm	28	451	6.2%	cbioportal
12	KDM5C	Ssm	27	451	6%	cbioportal
11	DNAH3	Ssm	27	451	6%	cbioportal
13	HMCN1	Ssm	26	451	5.8%	cbioportal
16	TSHZ3	Ssm	25	451	5.5%	cbioportal
14	ARAP3	Ssm	25	451	5.5%	cbioportal
15	ARID1A	Ssm	25	451	5.5%	cbioportal
17	SSH2	Ssm	24	451	5.3%	cbioportal
21	VWF	Ssm	23	451	5.1%	cbioportal
20	SPEN	Ssm	23	451	5.1%	cbioportal
19	NAV3	Ssm	23	451	5.1%	cbioportal
18	AKAP9	Ssm	23	451	5.1%	cbioportal
26	PDZD2	Ssm	22	451	4.9%	cbioportal
22	ABCA1	Ssm	22	451	4.9%	cbioportal
23	CD4	Ssm	22	451	4.9%	cbioportal
24	GRIN2B	Ssm	22	451	4.9%	cbioportal
25	MAP1B	Ssm	22	451	4.9%	cbioportal
29	DDB1	Ssm	21	451	4.7%	cbioportal
27	ABCA6	Ssm	21	451	4.7%	cbioportal
28	DCHS1	Ssm	21	451	4.7%	cbioportal
30	DNMT1	Ssm	21	451	4.7%	cbioportal

Data updated 22 days agoSource updated 2026-01-07

Kidney Renal Clear Cell Carcinoma (TCGA, Nature 2013) kirc_tcga_pubTCGA

426 cases with simple somatic mutation data · 446 cases total · 2026-02-19 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	218	426	51.2%	cbioportal
2	PBRM1	Ssm	145	426	34%	cbioportal
3	MUC4	Ssm	90	426	21.1%	cbioportal
4	TTN	Ssm	63	426	14.8%	cbioportal
5	SETD2	Ssm	55	426	12.9%	cbioportal
6	BAP1	Ssm	42	426	9.9%	cbioportal
7	MUC16	Ssm	34	426	8%	cbioportal
8	KDM5C	Ssm	29	426	6.8%	cbioportal
9	MTOR	Ssm	23	426	5.4%	cbioportal
10	PABPC1	Ssm	19	426	4.5%	cbioportal
11	HMCN1	Ssm	18	426	4.2%	cbioportal
14	PTEN	Ssm	17	426	4%	cbioportal
12	AHNAK2	Ssm	17	426	4%	cbioportal
13	KMT2C	Ssm	17	426	4%	cbioportal
15	USH2A	Ssm	17	426	4%	cbioportal
16	MACF1	Ssm	16	426	3.8%	cbioportal
17	MAGEC1	Ssm	16	426	3.8%	cbioportal
19	DNAH9	Ssm	15	426	3.5%	cbioportal
18	ADGRV1	Ssm	15	426	3.5%	cbioportal
20	LRP1B	Ssm	15	426	3.5%	cbioportal
21	PCLO	Ssm	15	426	3.5%	cbioportal
22	SYNE1	Ssm	15	426	3.5%	cbioportal
25	DST	Ssm	14	426	3.3%	cbioportal
26	KMT2D	Ssm	14	426	3.3%	cbioportal
23	ARID1A	Ssm	14	426	3.3%	cbioportal
24	ATM	Ssm	14	426	3.3%	cbioportal
27	FBN2	Ssm	13	426	3.1%	cbioportal
29	MUC17	Ssm	13	426	3.1%	cbioportal
30	MUC2	Ssm	13	426	3.1%	cbioportal
28	FMN2	Ssm	13	426	3.1%	cbioportal

Data updated 22 days agoSource updated 2026-02-19

Kidney Renal Clear Cell Carcinoma (TCGA, PanCancer Atlas) kirc_tcga_pan_can_atlas_2018TCGA

402 cases with simple somatic mutation data · 512 cases total · 2026-06-05 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	166	402	41.3%	cbioportal
2	PBRM1	Ssm	145	402	36.1%	cbioportal
3	TTN	Ssm	69	402	17.2%	cbioportal
4	SETD2	Ssm	49	402	12.2%	cbioportal
5	BAP1	Ssm	38	402	9.5%	cbioportal
6	MTOR	Ssm	31	402	7.7%	cbioportal
7	MUC16	Ssm	30	402	7.5%	cbioportal
8	KDM5C	Ssm	20	402	5%	cbioportal
9	DNAH9	Ssm	18	402	4.5%	cbioportal
11	HMCN1	Ssm	17	402	4.2%	cbioportal
10	CSMD3	Ssm	17	402	4.2%	cbioportal
12	FBN2	Ssm	16	402	4%	cbioportal
16	PCLO	Ssm	15	402	3.7%	cbioportal
15	MACF1	Ssm	15	402	3.7%	cbioportal
14	LRP2	Ssm	15	402	3.7%	cbioportal
13	KMT2C	Ssm	15	402	3.7%	cbioportal
17	XIRP2	Ssm	15	402	3.7%	cbioportal
22	SPEN	Ssm	14	402	3.5%	cbioportal
21	FLG	Ssm	14	402	3.5%	cbioportal
20	DST	Ssm	14	402	3.5%	cbioportal
19	ARID1A	Ssm	14	402	3.5%	cbioportal
18	AHNAK2	Ssm	14	402	3.5%	cbioportal
23	ABCA13	Ssm	13	402	3.2%	cbioportal
29	PKHD1L1	Ssm	13	402	3.2%	cbioportal
28	NEB	Ssm	13	402	3.2%	cbioportal
27	MUC17	Ssm	13	402	3.2%	cbioportal
26	LRP1B	Ssm	13	402	3.2%	cbioportal
25	DNAH2	Ssm	13	402	3.2%	cbioportal
24	ATM	Ssm	13	402	3.2%	cbioportal
30	USH2A	Ssm	13	402	3.2%	cbioportal

Data updated 22 days agoSource updated 2026-06-05

Metastatic Renal Clear Cell Carcinoma (Phase 1 Biomarker Trial, Clin Cancer Res. 2016) - iAtlas Harmonized ccrcc_iatlas_choueiri_2016

16 cases with simple somatic mutation data · 16 cases total · 2026-02-16 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	SETD2	Ssm	10	16	62.5%	cbioportal
2	VHL	Ssm	8	16	50%	cbioportal
3	PBRM1	Ssm	6	16	37.5%	cbioportal
6	ZFC3H1	Ssm	4	16	25%	cbioportal
4	BTG4	Ssm	4	16	25%	cbioportal
5	FBXL13	Ssm	4	16	25%	cbioportal
22	UBR4	Ssm	3	16	18.8%	cbioportal
21	TTN	Ssm	3	16	18.8%	cbioportal
20	SYNE1	Ssm	3	16	18.8%	cbioportal
19	SRPK1	Ssm	3	16	18.8%	cbioportal
18	SPEF2	Ssm	3	16	18.8%	cbioportal
17	SLC9A9	Ssm	3	16	18.8%	cbioportal
7	ARHGAP39	Ssm	3	16	18.8%	cbioportal
8	CENPB	Ssm	3	16	18.8%	cbioportal
9	DMXL2	Ssm	3	16	18.8%	cbioportal
10	FNDC1	Ssm	3	16	18.8%	cbioportal
11	HEATR1	Ssm	3	16	18.8%	cbioportal
12	HUWE1	Ssm	3	16	18.8%	cbioportal
13	LRP2	Ssm	3	16	18.8%	cbioportal
14	MYO10	Ssm	3	16	18.8%	cbioportal
15	PRKDC	Ssm	3	16	18.8%	cbioportal
16	SCUBE2	Ssm	3	16	18.8%	cbioportal
24	WDR47	Ssm	3	16	18.8%	cbioportal
23	VCPIP1	Ssm	3	16	18.8%	cbioportal
28	ADAMTSL3	Ssm	2	16	12.5%	cbioportal
29	ADAR	Ssm	2	16	12.5%	cbioportal
30	AGBL2	Ssm	2	16	12.5%	cbioportal
25	ABCA5	Ssm	2	16	12.5%	cbioportal
26	ABCC2	Ssm	2	16	12.5%	cbioportal
27	ADAMTS20	Ssm	2	16	12.5%	cbioportal

Data updated 22 days agoSource updated 2026-02-16

Renal Cell Carcinoma (St. James, Clin Cancer Res 2023) ccrcc_sjuh_2023St. James

943 cases with simple somatic mutation data · 943 cases total · 2026-03-09 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved12 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	642	943	68.1%	cbioportal
2	PBRM1	Ssm	325	943	34.5%	cbioportal
3	SETD2	Ssm	151	943	16%	cbioportal
4	BAP1	Ssm	119	943	12.6%	cbioportal
5	KDM5C	Ssm	67	943	7.1%	cbioportal
6	ATM	Ssm	31	943	3.3%	cbioportal
8	TP53	Ssm	29	943	3.1%	cbioportal
7	DMD	Ssm	29	943	3.1%	cbioportal
9	COL11A1	Ssm	21	943	2.2%	cbioportal
10	TRRAP	Ssm	12	943	1.3%	cbioportal
11	PTK7	Ssm	6	943	0.6%	cbioportal
12	ATP9B	Ssm	5	943	0.5%	cbioportal

Data updated 22 days agoSource updated 2026-03-09

Renal Clear Cell Carcinoma (TCGA GDC, 2025) ccrcc_tcga_gdcTCGA GDC

375 cases with simple somatic mutation data · 537 cases total · 2026-01-13 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	172	375	45.9%	cbioportal
2	PBRM1	Ssm	147	375	39.2%	cbioportal
3	TTN	Ssm	63	375	16.8%	cbioportal
4	SETD2	Ssm	46	375	12.3%	cbioportal
5	BAP1	Ssm	40	375	10.7%	cbioportal
6	MUC16	Ssm	29	375	7.7%	cbioportal
7	MTOR	Ssm	27	375	7.2%	cbioportal
8	KDM5C	Ssm	20	375	5.3%	cbioportal
10	DST	Ssm	19	375	5.1%	cbioportal
9	DNAH9	Ssm	19	375	5.1%	cbioportal
11	ATM	Ssm	17	375	4.5%	cbioportal
12	CSMD3	Ssm	17	375	4.5%	cbioportal
13	FBN2	Ssm	16	375	4.3%	cbioportal
15	KMT2C	Ssm	16	375	4.3%	cbioportal
16	LRP2	Ssm	16	375	4.3%	cbioportal
14	HMCN1	Ssm	16	375	4.3%	cbioportal
17	AHNAK2	Ssm	15	375	4%	cbioportal
21	USH2A	Ssm	14	375	3.7%	cbioportal
18	ANK3	Ssm	14	375	3.7%	cbioportal
19	SPEN	Ssm	14	375	3.7%	cbioportal
20	SYNE1	Ssm	14	375	3.7%	cbioportal
25	PTEN	Ssm	13	375	3.5%	cbioportal
23	MUC17	Ssm	13	375	3.5%	cbioportal
22	DNAH2	Ssm	13	375	3.5%	cbioportal
24	PCLO	Ssm	13	375	3.5%	cbioportal
28	LRP1B	Ssm	12	375	3.2%	cbioportal
27	FLG	Ssm	12	375	3.2%	cbioportal
26	ARID1A	Ssm	12	375	3.2%	cbioportal
30	XIRP2	Ssm	12	375	3.2%	cbioportal
29	PKHD1L1	Ssm	12	375	3.2%	cbioportal

Data updated 22 days agoSource updated 2026-01-13

Renal Clear Cell Carcinoma (UTokyo, Nat Genet 2013) ccrcc_utokyo_2013UTokyo

106 cases with simple somatic mutation data · 106 cases total · 2026-01-05 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	VHL	Ssm	43	106	40.6%	cbioportal
2	PBRM1	Ssm	31	106	29.2%	cbioportal
3	TTN	Ssm	21	106	19.8%	cbioportal
4	MUC16	Ssm	15	106	14.2%	cbioportal
5	SETD2	Ssm	12	106	11.3%	cbioportal
6	BAP1	Ssm	9	106	8.5%	cbioportal
7	CSMD3	Ssm	8	106	7.5%	cbioportal
8	AHNAK2	Ssm	7	106	6.6%	cbioportal
11	KMT2C	Ssm	6	106	5.7%	cbioportal
14	TET2	Ssm	6	106	5.7%	cbioportal
13	MUC4	Ssm	6	106	5.7%	cbioportal
12	MTOR	Ssm	6	106	5.7%	cbioportal
10	HMCN1	Ssm	6	106	5.7%	cbioportal
9	FRYL	Ssm	6	106	5.7%	cbioportal
20	ZNF536	Ssm	5	106	4.7%	cbioportal
16	KCNMA1	Ssm	5	106	4.7%	cbioportal
17	KEAP1	Ssm	5	106	4.7%	cbioportal
18	PIK3CA	Ssm	5	106	4.7%	cbioportal
19	PKHD1	Ssm	5	106	4.7%	cbioportal
15	ELOC	Ssm	5	106	4.7%	cbioportal
29	HYDIN	Ssm	4	106	3.8%	cbioportal
28	GRB7	Ssm	4	106	3.8%	cbioportal
27	EP300	Ssm	4	106	3.8%	cbioportal
26	DNAH3	Ssm	4	106	3.8%	cbioportal
25	DNAH11	Ssm	4	106	3.8%	cbioportal
21	ARHGEF28	Ssm	4	106	3.8%	cbioportal
22	BCL11A	Ssm	4	106	3.8%	cbioportal
23	CACNA1G	Ssm	4	106	3.8%	cbioportal
24	CUBN	Ssm	4	106	3.8%	cbioportal
30	IQGAP2	Ssm	4	106	3.8%	cbioportal

Data updated 22 days agoSource updated 2026-01-05

Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017NIH

16 cases with simple somatic mutation data · 16 cases total · 2026-01-13 · mapped to Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	7	16	43.8%	cbioportal
2	KMT2C	Ssm	5	16	31.3%	cbioportal
3	TAF1	Ssm	4	16	25%	cbioportal
4	ZNF717	Ssm	4	16	25%	cbioportal
5	AGAP4	Ssm	3	16	18.8%	cbioportal
6	FAM136A	Ssm	3	16	18.8%	cbioportal
7	PIK3CA	Ssm	3	16	18.8%	cbioportal
30	GART	Ssm	2	16	12.5%	cbioportal
8	ABCD1	Ssm	2	16	12.5%	cbioportal
9	AHNAK2	Ssm	2	16	12.5%	cbioportal
10	AP3D1	Ssm	2	16	12.5%	cbioportal
11	ARID1A	Ssm	2	16	12.5%	cbioportal
12	ASTE1	Ssm	2	16	12.5%	cbioportal
13	CCDC178	Ssm	2	16	12.5%	cbioportal
14	CHL1	Ssm	2	16	12.5%	cbioportal
15	CHRM5	Ssm	2	16	12.5%	cbioportal
16	COIL	Ssm	2	16	12.5%	cbioportal
17	COL5A1	Ssm	2	16	12.5%	cbioportal
18	DENND4A	Ssm	2	16	12.5%	cbioportal
19	DMAP1	Ssm	2	16	12.5%	cbioportal
20	DNAH11	Ssm	2	16	12.5%	cbioportal
21	DNAH3	Ssm	2	16	12.5%	cbioportal
22	DST	Ssm	2	16	12.5%	cbioportal
23	DYSF	Ssm	2	16	12.5%	cbioportal
24	EPC2	Ssm	2	16	12.5%	cbioportal
25	ERBB3	Ssm	2	16	12.5%	cbioportal
26	FAT3	Ssm	2	16	12.5%	cbioportal
27	FOXA2	Ssm	2	16	12.5%	cbioportal
28	FRG1	Ssm	2	16	12.5%	cbioportal
29	FRG2C	Ssm	2	16	12.5%	cbioportal

Data updated 22 days agoSource updated 2026-01-13