CUL7 — gene · CancerIndex

Curated evidence

Clinical evidence (2)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CUL7 Overexpression2
(prognostic)	Brain GliomaUNRESOLVED	Prognostic	B	Supports Poor Outcome	4	submitted	EID8087 The expression of CUL7 was found to be significantly higher in glioma samples than normal brain tissue, and increased with tumour grade. The prognostic value of CUL7 was examined in TCGA LGG (n=457) a… (full text at CIViC) PMID 32252802 · Xu et al., 2020 · Open in CIViC	civic
〃	GlioblastomaCURATED_BROADER	Prognostic	B	Supports Poor Outcome	4	submitted	EID8088 The expression of CUL7 was found to be significantly higher in glioma samples than normal brain tissue, and increased with tumour grade. The prognostic value of CUL7 was examined in TCGA LGG (n=457) a… (full text at CIViC) PMID 32252802 ·

Cohorts

Alteration frequency by cohort (12)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved12 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Metaplastic Breast Cancer (MSK,NPJ Breast Cancer 2021) mbc_msk_2021	Breast Metaplastic Carcinoma	Ssm	1

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.