Molecular Subtype
Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA
CI-CAN-00009229Explore in graph →
Hematologic6 active trials5 evidence items
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Molecular Subtype
CI-CAN-00009229Explore in graph →
Data completeness3 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
An acute promyelocytic leukemia characterized by the reciprocal balanced translocation t(15;17)(q24.1;q21.2) that results in the fusion of the promyelocytic leukemia (PML) gene and retinoic acid receptor-alpha (RARA) gene. The t(15;17)(q24.1;q21.2) with the resulting PML-RARA fusion gene occurs in over 95% of cases of acute promyelocytic leukemia. The remainder of the cases show variant RARA gene translocations with other genes.
Data updated 22 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Parents
Anatomy
Data updated 19 hours agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
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Data updated 19 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants