| Topotecan studied in …STUDIED_INderived200 of 372show all (up to 200) |
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| → studied in | NCT02502266Phase 2/Phase 3 · active not recruiting Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Fallopian Tube Endometrioid Adenocarcinoma,Ovarian Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06619236Phase 3 · active not recruiting Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Platinum-Resistant Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07099898Phase 3 · recruiting A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301] · 372 trials list this drug (67 active) | — | — | Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07194044Phase 1 · recruiting Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes · 372 trials list this drug (67 active) | — | — | Ewing Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06172296Phase 3 · recruiting Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma,Ganglioneuroblastoma, Nodular | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07365241Phase 3 · recruiting A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01857934Phase 2 · completed Therapy for Children With Advanced Stage Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07213804Phase 3 · recruiting A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Peritoneal Neoplasm,Fallopian Tube Neoplasm,Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05153239Phase 3 · completed Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05535166Phase 2 · recruiting Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma · 372 trials list this drug (67 active) | — | — | Medulloblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05990738Phase 1 · active not recruiting DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06612151Phase 3 · active not recruiting A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer (TAISHAN-302) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01012817Phase 1/Phase 2 · active not recruiting Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Solid Neoplasm,Malignant Solid Neoplasm,Primary Peritoneal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06449209Phase 2 · active not recruiting Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04514497Phase 1 · active not recruiting Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer · 372 trials list this drug (67 active) | — | — | Malignant Solid Neoplasm,Malignant Lung Neoplasm,Malignant Pancreatic Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07437963Phase 1/Phase 2 · not yet recruiting Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse · 372 trials list this drug (67 active) | — | — | Ganglioneuroblastoma,Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07604766Phase 3 · recruiting An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in China · 372 trials list this drug (67 active) | — | — | Platinum-Resistant Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02114229Phase 2 · active not recruiting Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors · 372 trials list this drug (67 active) | — | — | Rhabdoid Tumor,Atypical Teratoid/Rhabdoid Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07797153Phase 3 · not yet recruiting JSKN033 Versus Investigator's Choice of Chemotherapy in Recurrent or Metastatic Cervical Cancer · 372 trials list this drug (67 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06459180Phase 3 · active not recruiting A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20) · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06528496Phase 2 · recruiting N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma,Childhood Neuroblastoma,High Risk Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03126916Phase 3 · recruiting Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) · 372 trials list this drug (67 active) | — | — | Ganglioneuroblastoma,Neuroblastoma,Ganglioneuroblastoma, Nodular | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04322318Phase 2 · recruiting A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT · 372 trials list this drug (67 active) | — | — | Anaplastic Kidney Wilms Tumor,Kidney Wilms Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06647953Phase 3 · recruiting Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma · 372 trials list this drug (67 active) | — | — | Pleuropulmonary Blastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04106219Phase 1 · active not recruiting A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06801834Phase 3 · recruiting Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04947501early Phase 1 · active not recruiting A Study of N9 Chemotherapy in Children With Neuroblastoma · 372 trials list this drug (67 active) | — | — | Childhood Malignant Neoplasm,Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06203210Phase 3 · recruiting A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02101788Phase 2/Phase 3 · completed Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer · 372 trials list this drug (67 active) | — | — | Borderline Ovarian Serous Tumor,Micropapillary Serous Carcinoma,Ovarian Serous Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04739800Phase 2 · active not recruiting Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents · 372 trials list this drug (67 active) | — | — | Low Grade Fallopian Tube Serous Adenocarcinoma,Fallopian Tube Endometrioid Adenocarcinoma,Ovarian Seromucinous Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03896503Phase 2 · active not recruiting Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs · 372 trials list this drug (67 active) | — | — | Extrapulmonary Small Cell Neuroendocrine Carcinoma,Lung Small Cell Carcinoma,Platinum-Resistant Lung Small Cell Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06161025Phase 2/Phase 3 · recruiting A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07218809Phase 3 · recruiting AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05652686Phase 1/Phase 2 · recruiting A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) · 372 trials list this drug (67 active) | — | — | Neuroendocrine Carcinoma,Extrapulmonary Neuroendocrine Carcinoma,Large Cell Neuroendocrine Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07286266Phase 3 · recruiting A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01) · 372 trials list this drug (67 active) | — | — | Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02813135Phase 1/Phase 2 · recruiting European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors · 372 trials list this drug (67 active) | — | — | Childhood Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07321912Phase 2 · recruiting Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma · 372 trials list this drug (67 active) | — | — | Ewing Sarcoma,Osteosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01783535Phase 2 · active not recruiting Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma · 372 trials list this drug (67 active) | — | — | Retinoblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07545460Phase 3 · not yet recruiting A Study Comparing BL-M07D1 With Physician's Choice of Chemotherapy in Patients With HER2-Expressing Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00308165Phase 1 · completed Topotecan by Intracerebral Clysis for Recurrent Primary Malignant Brain Tumors · 372 trials list this drug (67 active) | — | — | Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03289910Phase 2 · active not recruiting Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia · 372 trials list this drug (67 active) | — | — | Myelodysplastic/Myeloproliferative Neoplasm,Acute Myeloid Leukemia,Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06666712Phase 1 · recruiting Chronic CED of TPT for Recurrent Malignant Glioma · 372 trials list this drug (67 active) | — | — | Brain Neoplasm,Malignant Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05521984Phase 1 · recruiting Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) · 372 trials list this drug (67 active) | — | — | Childhood Solid Neoplasm,Childhood Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04994977Phase 1 · terminated Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery · 372 trials list this drug (67 active) | — | — | Atypical Choroid Plexus Papilloma,Choroid Plexus Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03786783Phase 2 · completed Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma · 372 trials list this drug (67 active) | — | — | Ganglioneuroblastoma,High Risk Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06930755Phase 1 · recruiting Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05800587Phase 2 · recruiting Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06616532Phase 3 · active not recruiting PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05353439Phase 1 · active not recruiting Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma,Platinum-Resistant Lung Small Cell Carcinoma,Platinum-Sensitive Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02308527Phase 2 · completed Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02354547Phase 1 · suspended A Study of SGT-53 in Children With Refractory or Recurrent Solid Tumors · 372 trials list this drug (67 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05613088Phase 2 · completed A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03154996Phase 1 · completed Chronic Convection Enhanced Delivery of Topotecan · 372 trials list this drug (67 active) | — | — | Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05101551Phase 1 · recruiting Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy · 372 trials list this drug (67 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06828354Phase 3 · recruiting A Study of SHR-A1811 in Subjects With Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06500026Phase 3 · active not recruiting A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer(PANKU-Lung03) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07418749Phase 3 · recruiting A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02298348Phase 1 · active not recruiting Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04697628Phase 3 · completed Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01175356Phase 1 · completed Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin · 372 trials list this drug (67 active) | — | — | Ganglioneuroblastoma,Neuroblastoma,Regional Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01231906Phase 3 · completed Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma · 372 trials list this drug (67 active) | — | — | Extraskeletal Ewing Sarcoma,Peripheral Primitive Neuroectodermal Tumor of Bone,Peripheral Primitive Neuroectodermal Tumor of Soft Tissues | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07334301Phase 1/Phase 2 · recruiting A Multi-Arm, Platform Trial For Relapsed Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05740566Phase 3 · active not recruiting Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07189455Phase 3 · recruiting Study Comparing ZG006 With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06855069Phase 3 · recruiting HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02364713Phase 2 · terminated MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Fallopian Tube Endometrioid Adenocarcinoma,Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05429502Phase 1 · terminated Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02514447Phase 1/Phase 2 · completed Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapy · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05870748Phase 2/Phase 3 · terminated REFRaME-O1: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1 · 372 trials list this drug (67 active) | — | — | Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm,Ovarian Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03107988Phase 1 · completed NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922) · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04908787Phase 3 · completed A Phase III Study of BD0801 Combined With Chemotherapy in Recurrent, Platinum-resistant Epithelial Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05874401Phase 4 · recruiting Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05092360Phase 3 · terminated Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7) · 372 trials list this drug (67 active) | — | — | Malignant Fallopian Tube Neoplasm,Platinum-Resistant Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04209855Phase 3 · completed A Study of Mirvetuximab Soravtansine vs. Investigator's Choice (IC) of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha (FRα) Expression · 372 trials list this drug (67 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01931098Phase 2 · completed Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab · 372 trials list this drug (67 active) | — | — | Central Nervous System Neoplasm,Glioblastoma,Brain Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07106528Phase 2/Phase 3 · not yet recruiting Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07076095Phase 2 · not yet recruiting A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04239092Phase 1 · terminated 9-ING-41 in Pediatric Patients With Refractory Malignancies. · 372 trials list this drug (67 active) | — | — | Neoplasm,Malignant Neoplasm,Childhood Malignant Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06954246Phase 3 · recruiting A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02419495Phase 1 · terminated Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies · 372 trials list this drug (67 active) | — | — | Malignant Solid Neoplasm,Melanoma,Malignant Lung Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06972602early Phase 1 · recruiting High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed · 372 trials list this drug (67 active) | — | — | Retinoblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03554473Phase 1/Phase 2 · completed M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm,Small Cell Neuroendocrine Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02569957Phase 2 · terminated Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Malignant Ovarian Endometrioid Tumor,Malignant Ovarian Serous Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02487095Phase 1/Phase 2 · completed Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers · 372 trials list this drug (67 active) | — | — | Neuroendocrine Carcinoma,Ovarian Neoplasm,Lung Non-Small Cell Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00588991Phase 1 · completed Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders · 372 trials list this drug (67 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Myelodysplastic Syndrome,Secondary Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00638898Phase 1 · completed Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor · 372 trials list this drug (67 active) | — | — | Solid Neoplasm,Adult Solid Neoplasm,Childhood Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03088813Phase 3 · completed Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02030964Phase 1 · completed N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03709680Phase 2 · active not recruiting Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors · 372 trials list this drug (67 active) | — | — | Solid Neoplasm,Rhabdoid Tumor,Ewing Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06751485Phase 3 · not yet recruiting JSKN003 in Platinum-Resistant, Relapsed Epithelial Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04029688Phase 1/Phase 2 · terminated A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors · 372 trials list this drug (67 active) | — | — | Solid Neoplasm,Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06496048Phase 3 · recruiting Lurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLC · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02312245Phase 2 · completed Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Fallopian Tube Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05246111Phase 1 · completed Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208) · 372 trials list this drug (67 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00170625Phase 1/Phase 2 · completed Therapy With Topotecan and Carboplatin by Patients With Relapsed Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06498479Phase 3 · recruiting ARTEMIS-008：HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04768296Phase 2 · completed Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01904253Phase 2 · terminated A Phase 2 Study Comparing TAS-102 Versus Topotecan or Amrubicin to Treat Small Cell Lung Cancer Following Platinum-Based Chemotherapy · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06581380Phase 3 · not yet recruiting JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06548763Phase 2 · not yet recruiting Oral Topotecan With Toripalimab for Patients With Endometrial Cancer · 372 trials list this drug (67 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06394492Phase 3 · recruiting SHR-A1921 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00601003Phase 2 · completed Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma · 372 trials list this drug (67 active) | — | — | Medulloblastoma,Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01798004Phase 1 · completed Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma · 372 trials list this drug (67 active) | — | — | Ganglioneuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02200757Phase 2 · completed Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06128837Phase 3 · recruiting Study of LY01610 in Patients With Recurrent Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01606878Phase 1 · completed Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma · 372 trials list this drug (67 active) | — | — | Childhood Solid Neoplasm,Childhood Anaplastic Large Cell Lymphoma,Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02649673Phase 1 · terminated LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03600649Phase 1 · unknown Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas · 372 trials list this drug (67 active) | — | — | Ewing Sarcoma,Myoepithelial Tumor,Soft Tissue Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00657878Phase 3 · unknown Efficacy Study of Chemotherapy to Treat Ovarian Cancer Recurrence by Prolonging the Platinum Free Interval · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02584478Phase 3 · unknown Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Cervical Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04455139Phase 2 · terminated A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma · 372 trials list this drug (67 active) | — | — | Malignant Eye Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00856037Phase 1 · completed Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05295589Phase 2 · withdrawn Comparing Standard of Care Chemotherapy Treatment to the Combination of Copanlisib and Olaparib for Recurrent Platinum Resistant Ovarian Cancer That Has Progressed Through PARP Inhibitor Therapy · 372 trials list this drug (67 active) | — | — | Fallopian Tube Endometrioid Adenocarcinoma,Platinum-Resistant Primary Peritoneal Carcinoma,Primary Peritoneal Endometrioid Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01076400Phase 1/Phase 2 · terminated A Study of Adavosertib (MK-1775) in Combination With Topotecan/Cisplatin in Participants With Cervical Cancer (MK-1775-008) · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02481830Phase 3 · completed Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00057837Phase 2 · completed Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00005962Phase 2 · completed Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia · 372 trials list this drug (67 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03927274early Phase 1 · terminated Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma · 372 trials list this drug (67 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00744081Phase 2 · completed Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML) · 372 trials list this drug (67 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02963090Phase 2 · terminated Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04661852Phase 1 · completed Cabozantinib With Topotecan-Cyclophosphamide · 372 trials list this drug (67 active) | — | — | Ewing Sarcoma,Osteosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00014443Phase 2 · terminated Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma · 372 trials list this drug (67 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02866006Phase 1/Phase 2 · completed Safety and Tolerability Evaluation Study of BVAC-C in Patients With HPV Type 16 or 18 Positive Cervical Cancer · 372 trials list this drug (67 active) | — | — | Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04022876Phase 1 · terminated A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection) · 372 trials list this drug (67 active) | — | — | Lung Non-Small Cell Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04943627Phase 3 · withdrawn Balstilimab Versus Investigator Choice Chemotherapy in Patients With Recurrent Cervical Cancer (BRAVA) · 372 trials list this drug (67 active) | — | — | Malignant Neoplasm,Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05303727Phase 2 · not yet recruiting Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00976911Phase 3 · completed AURELIA: A Study of Avastin (Bevacizumab) Added to Chemotherapy in Patients With Platinum-resistant Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02357810Phase 2 · completed Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas · 372 trials list this drug (67 active) | — | — | Liposarcoma,Osteosarcoma,Adult Liposarcoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00567567Phase 3 · completed Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma,Regional Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01004874Phase 2 · completed Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma · 372 trials list this drug (67 active) | — | — | Glioblastoma,Malignant Glioma,Gliosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00317772Phase 1/Phase 2 · completed Topotecan and Gefitinib (Iressa) for Ovarian, Peritoneal, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02566993Phase 3 · completed Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00025272Phase 2 · completed Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04679064Phase 3 · unknown Trial on NIraparib-TSR-042 (Dostarlimab) vs Physician's Choice CHEmotherapy in Recurrent, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02903004Phase 3 · completed Trial on Trabectedin (ET-743) vs Clinician's Choice Chemotherapy in Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancers of BRCA Mutated or BRCAness Phenotype Patients · 372 trials list this drug (67 active) | — | — | Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00499616Phase 3 · completed Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04799002Phase 3 · recruiting Topotecan and Melphalan for Retinoblastoma · 372 trials list this drug (67 active) | — | — | Retinoblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03061812Phase 3 · completed Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03059667Phase 2 · completed Immunotherapy as Second-line in Patient With Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03227016Phase 1 · unknown Study in Patients With SCLC of Veliparib in Combination With Topotecan · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03098030Phase 2/Phase 3 · completed Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02631876Phase 3 · completed A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Women With Folate Receptor (FR) Alpha Positive Advanced Epithelial Ovarian Cancer (EOC), Primary Peritoneal or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00002950Phase 1/Phase 2 · completed Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer · 372 trials list this drug (67 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01803269Phase 2 · terminated Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00003372Phase 2 · completed Topotecan in Treating Patients With Recurrent Brain Tumors · 372 trials list this drug (67 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02390843Phase 1 · completed Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors · 372 trials list this drug (67 active) | — | — | Germ Cell Tumor,Hepatoblastoma,Rhabdoid Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02421588Phase 3 · completed Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00028743Phase 3 · completed Combination Chemotherapy Regimens in Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer · 372 trials list this drug (67 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00477282Phase 3 · completed Karenitecin Versus Topotecan in Patients With Advanced Epithelial Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02786719NA · completed High-Risk Neuroblastoma Chemotherapy Without G-CSF · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02684071Phase 2 · terminated Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors · 372 trials list this drug (67 active) | — | — | Childhood Atypical Teratoid/Rhabdoid Tumor,Childhood Medulloblastoma,Embryonal Tumor with Multilayered Rosettes, C19MC-Altered+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04213937Phase 2 · unknown Nab-paclitaxel Versus Topotecan As Second-Line Treatment for Patients With Extensive Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00005792Phase 1 · completed Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma · 372 trials list this drug (67 active) | — | — | Multiple Myeloma,Plasma Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00547651Phase 3 · completed AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapy · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04073550Phase 3 · unknown Study of Anlotinib Hydrochloride Capsule in Subjects With Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01266447Phase 2 · completed Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer · 372 trials list this drug (67 active) | — | — | Cervical Adenocarcinoma,Cervical Squamous Cell Carcinoma,Cervical Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00803062Phase 3 · completed Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer · 372 trials list this drug (67 active) | — | — | Cervical Adenocarcinoma,Cervical Squamous Cell Carcinoma,Cervical Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00011986Phase 3 · completed Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Primary Peritoneal Carcinoma,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00652691Phase 1 · completed Topotecan, High-Dose Cyclophosphamide, Carboplatin, and an Autologous Peripheral Blood Cell Transplant in Treating Patients With Recurrent Ovarian Cancer or Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00003194Phase 1 · terminated Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors · 372 trials list this drug (67 active) | — | — | Childhood Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02500459early Phase 1 · terminated Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection · 372 trials list this drug (67 active) | — | — | Brain Neoplasm,High-Grade Glioma, NOS | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03193463early Phase 1 · withdrawn Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy · 372 trials list this drug (67 active) | — | — | Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03367182completed Real-World Effectiveness of Bevacizumab Based on AURELIA in Platinum-resistant Recurrent Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00087126Phase 2 · completed Topotecan in Treating Women With Persistent or Recurrent Cervical Cancer · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01497873Phase 2 · completed A Randomized Study to Compare the Efficacy and Safety of Belotecan and Topotecan as Monotherapy for Sensitive-Relapsed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03763123Phase 1 · unknown A Phase 1b Study of Sevacizumab in Combination With Chemotherapy in Chinese Patients With Platinum-Resistant Recurrent Ovarian Cancer. · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01039025Phase 2 · completed TMC (Topotecan, Cyclophosphamide and Melphalan) for Multiple Myeloma · 372 trials list this drug (67 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00038545Phase 2 · completed A Phase II Study of Paclitaxel and Topotecan With Filgrastim-SD/01 Support For Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma · 372 trials list this drug (67 active) | — | — | Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00064077Phase 3 · completed Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix · 372 trials list this drug (67 active) | — | — | Cervical Adenocarcinoma,Cervical Squamous Cell Carcinoma,Cervical Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00315211Phase 2 · terminated Weekly Topotecan With Docetaxel in Recurrent Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Mediastinal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00114166Phase 2 · completed Topotecan in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00098956Phase 2 · completed 7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00287963Phase 1 · completed Topotecan and Vinorelbine in Treating Patients With Recurrent Lung Cancer · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00005029Phase 2 · terminated Topotecan in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01654965Phase 1 · completed Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors · 372 trials list this drug (67 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00325416Phase 1/Phase 2 · completed Study of Melphalan and Topotecan (MT) Followed by Autologous Stem Cell Rescue in Patients With Multiple Myeloma. · 372 trials list this drug (67 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00257816Phase 2 · completed Weekly IV Topotecan and Cisplatin With Radiation in Cervical Carcinoma · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00720096NA · terminated Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan · 372 trials list this drug (67 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00365547Phase 2 · completed Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy · 372 trials list this drug (67 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00287911Phase 1 · completed Topotecan, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Cervical Cancer · 372 trials list this drug (67 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00287859Phase 1 · terminated Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer · 372 trials list this drug (67 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00361803Phase 1 · completed Topotecan Pharmacokinetic Characterization Study · 372 trials list this drug (67 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00158886Phase 1 · terminated Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer · 372 trials list this drug (67 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00259935Phase 1 · completed A Study To Determine If Two Different Versions Of Topotecan Have The Same Potency In Patients With Advanced Solid Tumors · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00483860Phase 1 · completed A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function · 372 trials list this drug (67 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00732420Phase 1 · completed Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors · 372 trials list this drug (67 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02100007Phase 1/Phase 2 · terminated ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors · 372 trials list this drug (67 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00109798NA · withdrawn Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma · 372 trials list this drug (67 active) | — | — | Central Nervous System Neoplasm,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01593228Phase 3 · completed Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial · 372 trials list this drug (67 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01736800Phase 2 · withdrawn Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors · 372 trials list this drug (67 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00828139Phase 2 · completed S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00004221Phase 2 · terminated Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III Ovarian Cancer · 372 trials list this drug (67 active) | — | — | Ovarian Neoplasm,Primary Peritoneal Carcinoma,Malignant Ovarian Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00541359Phase 1 · completed Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors · 372 trials list this drug (67 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00117013Phase 1 · completed A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1a · 372 trials list this drug (67 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00553189Phase 1 · completed Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and Lymphomas · 372 trials list this drug (67 active) | — | — | Solid Neoplasm,Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00061308Phase 2 · completed Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer · 372 trials list this drug (67 active) | — | — | Malignant Peritoneal Neoplasm,Ovarian Neoplasm,Malignant Fallopian Tube Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00043862Phase 2 · completed The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC) · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00046111Phase 1 · completed A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors · 372 trials list this drug (67 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00808899Phase 2 · terminated Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma · 372 trials list this drug (67 active) | — | — | Neuroblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01345279completed Indirect Comparison Topotecan Cervical Carcinoma · 372 trials list this drug (67 active) | — | — | Cervical Intraepithelial Neoplasia | 1 | Observed | clinicaltrials | graph → |