| Neratinib studied in …STUDIED_INderived71 of 71show fewer |
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| → studied in | NCT05564377Phase 2 · recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm,Primary Peritoneal Carcinoma,Malignant Female Reproductive System Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07152782Phase 2 · recruiting T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis · 71 trials list this drug (21 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06126276Phase 2 · recruiting Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial) · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm,Malignant Female Reproductive System Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05372614Phase 1 · recruiting Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm,Malignant Pancreatic Neoplasm,Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04886531Phase 2 · recruiting Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04374305Phase 2 · recruiting Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) · 71 trials list this drug (21 active) | — | — | Meningioma,Vestibular Schwannoma,Ependymoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02977780Phase 2 · recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT) · 71 trials list this drug (21 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05919108Phase 2 · recruiting Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers · 71 trials list this drug (21 active) | — | — | Invasive Breast Lobular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03065387Phase 1 · terminated Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03919292Phase 1/Phase 2 · suspended Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca · 71 trials list this drug (21 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06813079Phase 2 · recruiting Using Tumor Models to Determine Treatments · 71 trials list this drug (21 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06109467Phase 2 · active not recruiting Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer · 71 trials list this drug (21 active) | — | — | Gastric Neoplasm,Malignant Gastric Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05615818Phase 3 · recruiting Personalized Medicine for Advanced Biliary Cancer Patients · 71 trials list this drug (21 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04502602Phase 1 · active not recruiting Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer · 71 trials list this drug (21 active) | — | — | Solid Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01042379Phase 2 · recruiting I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer · 71 trials list this drug (21 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Early Stage Breast Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03377387Phase 1/Phase 2 · active not recruiting Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03101748Phase 1/Phase 2 · terminated Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,Breast Carcinoma,Breast Inflammatory Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01494662Phase 2 · completed HKI-272 for HER2-Positive Breast Cancer and Brain Metastases · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03289039Phase 2 · terminated Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05933395Phase 2 · recruiting Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02932280Phase 1/Phase 2 · active not recruiting Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment · 71 trials list this drug (21 active) | — | — | Solid Neoplasm,Central Nervous System Neoplasm,Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06008275early Phase 1 · recruiting Neratinib in Combination With Ruxolitinib in Patients With mTNBC · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04388384completed Real-life Pan-HER-blockade With Neratinib · 71 trials list this drug (21 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03094052Phase 2 · completed Incidence and Severity of Diarrhea in Patients With HER2 Positive Breast Cancer Treated With Trastuzumab and Neratinib · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,Breast Adenocarcinoma,HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07019272not yet recruiting Neratinib in Extended Adjuvant Treatment for HER2+ Early Breast Cancer With pCR But High-Risk Features: A Hebei Multi-Center Real-World Study · 71 trials list this drug (21 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05243641Phase 1/Phase 2 · terminated Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05252988Phase 2 · active not recruiting Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib · 71 trials list this drug (21 active) | — | — | Early Stage Breast Carcinoma,HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06083662Phase 2 · completed Neratinib and Trastuzumab Biosimilar in Patients with HER2 Mutated Advanced Solid Cancers · 71 trials list this drug (21 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05388149Phase 2 · recruiting Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06693024recruiting Adjuvant Therapy With Neratinib in HER2 Positive Early Breast Cancer · 71 trials list this drug (21 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06519110Phase 2 · unknown Neratinib Tablets Monotherapy for Advanced Solid Tumors With HER2 Mutations · 71 trials list this drug (21 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01953926Phase 2 · terminated Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations · 71 trials list this drug (21 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878524Phase 1 · terminated Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial · 71 trials list this drug (21 active) | — | — | Hematopoietic and Lymphatic System Neoplasm,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03812393Phase 2 · unknown Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negative Breast · 71 trials list this drug (21 active) | — | — | Early Stage Breast Carcinoma,HER2-Positive Breast Carcinoma,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04901299Phase 2 · withdrawn Fulvestrant + Neratinib In Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,Invasive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04781374Phase 2 · withdrawn Neratinib in Patients With Metastatic Castration-Resistant Prostate Cancer · 71 trials list this drug (21 active) | — | — | Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02673398Phase 2 · completed Neratinib in Treating Older Patients With Stage IV HER2-Positive Breast Cancer · 71 trials list this drug (21 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04366713Phase 2 · completed A Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib · 71 trials list this drug (21 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02236000Phase 1/Phase 2 · completed A Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05491057unknown Treatment Patterns of Neratinib in HER2+ EBC in China · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02400476Phase 2 · completed An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide · 71 trials list this drug (21 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01670877Phase 2 · completed Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer · 71 trials list this drug (21 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03457896Phase 2 · unknown Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status · 71 trials list this drug (21 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04856475Phase 2 · withdrawn Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05154396Phase 2 · unknown Neratinib Dose Escalation Regimen for HER2 Positive Early Breast Cancer · 71 trials list this drug (21 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01960023Phase 1/Phase 2 · withdrawn Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer · 71 trials list this drug (21 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01008150Phase 2 · completed Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00878709Phase 3 · completed Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01808573Phase 3 · completed A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic Setting · 71 trials list this drug (21 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03182634Phase 2 · unknown The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01128842Phase 1 · completed A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid Tumor · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00768469Phase 1 · completed Study Evaluating Safety And Tolerability, Solid Tumor · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01111825Phase 1/Phase 2 · completed Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00838539Phase 1 · completed Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors · 71 trials list this drug (21 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00146172Phase 1 · completed Study Evaluating HKI-272 in Tumors · 71 trials list this drug (21 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00397046Phase 1 · completed A Study Of The Safety And Tolerability Of HKI-272 Administered Orally To Japanese Subjects With Advanced Solid Tumors · 71 trials list this drug (21 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00741260Phase 1/Phase 2 · completed Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00915018Phase 2 · completed Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00300781Phase 2 · completed Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast Cancer · 71 trials list this drug (21 active) | — | — | Neoplasm,Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00706030Phase 1/Phase 2 · completed Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm,Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00777101Phase 2 · completed Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00445458Phase 1/Phase 2 · completed A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer · 71 trials list this drug (21 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00398567Phase 1/Phase 2 · completed A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01827267Phase 2 · completed Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer · 71 trials list this drug (21 active) | — | — | Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00958724Phase 1 · completed Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors · 71 trials list this drug (21 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00266877Phase 2 · completed Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung Cancer · 71 trials list this drug (21 active) | — | — | Lung Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02593708Phase 1 · terminated Phase1 of Neratinib+Trastuzumab, Pertuzumab, Paclitaxel in Patients With Advanced Solid Tumors/HER2+ · 71 trials list this drug (21 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00366600Phase 1 · completed Study Evaluating HKI-272 Administered to Healthy Subjects · 71 trials list this drug (21 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01956253no longer available Single Subject Neratinib in Bladder Cancer (NRR) · 71 trials list this drug (21 active) | — | — | Malignant Bladder Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01423123Phase 1 · completed Combination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast Cancer · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00708903Phase 1 · completed Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization) · 71 trials list this drug (21 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |