Imatinib Mesylate

Curated

← predicts response to

ABL1 G250ESNV

resistance

Curated

← predicts response to

ABL1 Y253HSNV

resistance

Curated

← predicts response to

ABL1 V299LSNV

resistance

Curated

← predicts response to

ABL1 Fusionfusion

33 source records aggregated

resistance

Curated

← predicts response to

ABL1 F359VSNV

3 source records aggregated

resistance

Curated

← predicts response to

ABL1 E255KSNV

3 source records aggregated

resistance

Curated

← predicts response to

ABL1 F359CSNV

3 source records aggregated

resistance

Curated

← predicts response to

ABL1 F317LSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 M244VSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 T315ISNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 M351TSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 E255VSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 Y253HSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 E459KSNV

resistance

Curated

Imatinib Mesylate targets …TARGETS4 of 4
→ targets	BCR	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	KIT	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	PDGFRB	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	ABL1	—	INHIBITOR	—	1	Curated	chembl	graph →

Imatinib Mesylate targets …TARGETS4 of 4

→ targets

BCR

—

INHIBITOR

—

Curated

→ targets

KIT

—

INHIBITOR

—

Curated

→ targets

PDGFRB

—

INHIBITOR

—

Curated

→ targets

ABL1

—

INHIBITOR

—

Curated

Imatinib Mesylate investigated for …INVESTIGATED_FOR67 of 67show fewer
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 3 source records aggregated	supports	B	Chronic Myeloid Leukemia, BCR-ABL1 Positive	3	Curated	civic	graph →
→ investigated for	Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy	unknown	4	Myelodysplastic/Myeloproliferative Neoplasm	1	Curated	chembl	graph →
→ investigated for	Dermatofibrosarcoma Protuberanssubtype	unknown	4	Dermatofibrosarcoma Protuberans	1	Curated	chembl	graph →
→ investigated for	Gastrointestinal Stromal Tumorsubtype	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	4	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	4	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 34 source records aggregated	supports	C	Chronic Myeloid Leukemia, BCR-ABL1 Positive	34	Curated	civic	graph →
→ investigated for	B Lymphoblastic Leukemia/Lymphomahematologic_malignancy	supports	C	B Lymphoblastic Leukemia/Lymphoma	1	Curated	civic	graph →
→ investigated for	Astrocytic Tumorsubtype	unknown	3	Astrocytic Tumor	1	Curated	chembl	graph →
→ investigated for	Myeloid Leukemiahematologic_malignancy	unknown	3	Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Acute Biphenotypic Leukemiahematologic_malignancy	unknown	3	Acute Biphenotypic Leukemia	1	Curated	chembl	graph →
→ investigated for	Lymphoid Leukemiahematologic_malignancy	unknown	3	Lymphoid Leukemia	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	3	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	3	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	3	Leukemia	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	3	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 31 source records aggregated	supports	D	Chronic Myeloid Leukemia, BCR-ABL1 Positive	31	Curated	civic	graph →
→ investigated for	Malignant Neoplasmcancer_family 2 source records aggregated	supports	D	Malignant Neoplasm	2	Curated	civic	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	supports	D	Lung Non-Small Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Chordomacancer_family	unknown	2	Chordoma	1	Curated	chembl	graph →
→ investigated for	Ovarian Carcinomasubtype	unknown	2	Ovarian Carcinoma	1	Curated	chembl	graph →
→ investigated for	Desmoid Fibromatosissubtype	unknown	2	Desmoid Fibromatosis	1	Curated	chembl	graph →
→ investigated for	Skin Neoplasmcancer_family	unknown	2	Skin Neoplasm	1	Curated	chembl	graph →
→ investigated for	T Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	2	T Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	2	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	2	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	2	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	2	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	2	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Central Nervous System Neoplasmcancer_family	unknown	2	Central Nervous System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Myeloproliferative Neoplasmhematologic_malignancy	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
→ investigated for	Thyroid Gland Neoplasmsubtype	unknown	2	Thyroid Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fibrosarcomasubtype	unknown	2	Fibrosarcoma	1	Curated	chembl	graph →
→ investigated for	Fibromasubtype	unknown	2	Fibroma	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	2	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	2	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	2	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	2	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	2	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	2	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Gastric Neoplasmcancer_family	unknown	2	Gastric Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	2	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Merkel Cell Carcinomasubtype	unknown	2	Merkel Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	2	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Chondrosarcomasubtype	unknown	2	Chondrosarcoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	2	Melanoma	1	Curated	chembl	graph →
→ investigated for	Schwannomasubtype	unknown	2	Schwannoma	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	2	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Polycythemia Verahematologic_malignancy	unknown	2	Polycythemia Vera	1	Curated	chembl	graph →
→ investigated for	Plexiform Neurofibromasubtype	unknown	2	Plexiform Neurofibroma	1	Curated	chembl	graph →
→ investigated for	Lymphangioleiomyomatosissubtype	unknown	1	Lymphangioleiomyomatosis	1	Curated	chembl	graph →
→ investigated for	Hematopoietic and Lymphoid Cell Neoplasmcancer_family	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	1	Endometrial Neoplasm	1	Curated	chembl	graph →
→ investigated for	Uterine Neoplasmsubtype	unknown	1	Uterine Neoplasm	1	Curated	chembl	graph →
→ investigated for	Thymomasubtype	unknown	1	Thymoma	1	Curated	chembl	graph →
→ investigated for	Desmoplastic Small Round Cell Tumorsubtype	unknown	1	Desmoplastic Small Round Cell Tumor	1	Curated	chembl	graph →
→ investigated for	Anaplastic Large Cell Lymphomahematologic_malignancy	unknown	1	Anaplastic Large Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	1	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	1	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Primary Myelofibrosishematologic_malignancy	unknown	1	Primary Myelofibrosis	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	1	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Synovial Sarcomasubtype	unknown	1	Synovial Sarcoma	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	0.5	Squamous Cell Carcinoma	1	Curated	chembl	graph →

Imatinib Mesylate investigated for …INVESTIGATED_FOR67 of 67show fewer

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

3 source records aggregated

supports

Curated

Myelodysplastic/Myeloproliferative Neoplasm

→ investigated for

Myelodysplastic/Myeloproliferative Neoplasmhematologic_malignancy

unknown

Curated

Dermatofibrosarcoma Protuberans

→ investigated for

Dermatofibrosarcoma Protuberanssubtype

unknown

Curated

Gastrointestinal Stromal Tumor

→ investigated for

Gastrointestinal Stromal Tumorsubtype

unknown

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

34 source records aggregated

supports

Curated

B Lymphoblastic Leukemia/Lymphoma

→ investigated for

B Lymphoblastic Leukemia/Lymphomahematologic_malignancy

supports

Curated

→ investigated for

Astrocytic Tumorsubtype

unknown

Astrocytic Tumor

Curated

→ investigated for

Myeloid Leukemiahematologic_malignancy

unknown

Myeloid Leukemia

Curated

Acute Biphenotypic Leukemia

→ investigated for

Acute Biphenotypic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Lymphoid Leukemiahematologic_malignancy

unknown

Lymphoid Leukemia

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

Leukemiacancer_family

unknown

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

31 source records aggregated

supports

Curated

→ investigated for

Malignant Neoplasmcancer_family

2 source records aggregated

supports

Malignant Neoplasm

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

supports

Curated

→ investigated for

Chordomacancer_family

unknown

Chordoma

Curated

→ investigated for

Ovarian Carcinomasubtype

unknown

Ovarian Carcinoma

Curated

→ investigated for

Desmoid Fibromatosissubtype

unknown

Desmoid Fibromatosis

Curated

→ investigated for

Skin Neoplasmcancer_family

unknown

Skin Neoplasm

Curated

T Acute Lymphoblastic Leukemia

→ investigated for

T Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

Central Nervous System Neoplasm

→ investigated for

Central Nervous System Neoplasmcancer_family

unknown

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

Myeloproliferative Neoplasm

→ investigated for

Myeloproliferative Neoplasmhematologic_malignancy

unknown

Curated

→ investigated for

Thyroid Gland Neoplasmsubtype

unknown

Thyroid Gland Neoplasm

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

→ investigated for

Fibrosarcomasubtype

unknown

Fibrosarcoma

Curated

→ investigated for

Fibromasubtype

unknown

Fibroma

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Gastric Neoplasmcancer_family

unknown

Gastric Neoplasm

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Merkel Cell Carcinomasubtype

unknown

Merkel Cell Carcinoma

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Chondrosarcomasubtype

unknown

Chondrosarcoma

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Schwannomasubtype

unknown

Schwannoma

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Polycythemia Verahematologic_malignancy

unknown

Polycythemia Vera

Curated

→ investigated for

Plexiform Neurofibromasubtype

unknown

Plexiform Neurofibroma

Curated

→ investigated for

Lymphangioleiomyomatosissubtype

unknown

Lymphangioleiomyomatosis

Curated

Hematopoietic and Lymphoid Cell Neoplasm

→ investigated for

Hematopoietic and Lymphoid Cell Neoplasmcancer_family

unknown

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

Endometrial Neoplasm

Curated

→ investigated for

Uterine Neoplasmsubtype

unknown

Uterine Neoplasm

Curated

→ investigated for

Thymomasubtype

unknown

Thymoma

Curated

Desmoplastic Small Round Cell Tumor

→ investigated for

Desmoplastic Small Round Cell Tumorsubtype

unknown

Curated

Anaplastic Large Cell Lymphoma

→ investigated for

Anaplastic Large Cell Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Primary Myelofibrosishematologic_malignancy

unknown

Primary Myelofibrosis

Curated

→ investigated for

Prostate Neoplasmsubtype

unknown

Prostate Neoplasm

Curated

→ investigated for

Synovial Sarcomasubtype

unknown

Synovial Sarcoma

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

0.5

Squamous Cell Carcinoma

Curated

Imatinib Mesylate investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 142show all (up to 200)
→ investigated in trials for	Leukemiacancer_family 41 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Leukemia	41	Observed	clinicaltrials	graph →
→ investigated in trials for	Gastrointestinal Stromal Tumorsubtype 32 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Gastrointestinal Stromal Tumor	32	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 16 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Acute Lymphoblastic Leukemia 7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Acute Lymphoblastic Leukemia	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive 7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Solid Neoplasm 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Solid Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive 6 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Prostate Neoplasm 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Prostate Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Sarcomacancer_family 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Sarcoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Childhood Acute Lymphoblastic Leukemia 5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Childhood Acute Lymphoblastic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Myeloid Leukemiahematologic_malignancy 5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myeloid Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive 4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Myelomonocytic Leukemia 4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Myelomonocytic Leukemia	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	4	Observed	clinicaltrials	graph →

Imatinib Mesylate investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 142show all (up to 200)

→ investigated in trials for

Leukemiacancer_family

41 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Gastrointestinal Stromal Tumor

→ investigated in trials for

Gastrointestinal Stromal Tumorsubtype

32 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

16 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Adult Acute Lymphoblastic Leukemia

→ investigated in trials for

7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Acute Lymphoblastic Leukemia

Observed

Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated in trials for

7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Observed

→ investigated in trials for

Adult Solid Neoplasm

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Solid Neoplasm

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated in trials for

6 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Observed

Malignant Prostate Neoplasm

→ investigated in trials for

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Prostate Neoplasm

Observed

→ investigated in trials for

Sarcomacancer_family

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Sarcoma

Observed

Childhood Acute Lymphoblastic Leukemia

→ investigated in trials for

5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Childhood Acute Lymphoblastic Leukemia

Observed

→ investigated in trials for

Myeloid Leukemiahematologic_malignancy

5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Myeloid Leukemia

Observed

Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated in trials for

4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Observed

Chronic Myelomonocytic Leukemia

→ investigated in trials for

4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Chronic Myelomonocytic Leukemia

Observed

Malignant Breast Neoplasm

→ investigated in trials for

4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Breast Neoplasm

Observed

→ investigated in trials for

Malignant Lung Neoplasm

4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Lung Neoplasm

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Imatinib Mesylate studied in …STUDIED_INderived10 of 188show all (up to 200)
→ studied in	NCT03516279Phase 2 · active not recruiting Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease · 188 trials list this drug (6 active)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT00070499Phase 2 · active not recruiting Imatinib Mesylate or Dasatinib in Treating Patients With Previously Untreated Chronic Phase Chronic Myelogenous Leukemia · 188 trials list this drug (6 active)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT03007147Phase 3 · active not recruiting Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia · 188 trials list this drug (6 active)	—	—	Acute Lymphoblastic Leukemia,B Acute Lymphoblastic Leukemia,T Acute Lymphoblastic Leukemia+1	1	Observed	clinicaltrials	graph →
→ studied in	NCT01742299Phase 4 · completed Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator · 188 trials list this drug (6 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT06655246Phase 1 · recruiting A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) · 188 trials list this drug (6 active)	—	—	Gastrointestinal Stromal Tumor,Malignant Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00015847Phase 2 · terminated Imatinib Mesylate and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia · 188 trials list this drug (6 active)	—	—	Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT05385549Phase 2 · recruiting 5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk · 188 trials list this drug (6 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT01751425Phase 1 · terminated Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase Inhibitors · 188 trials list this drug (6 active)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive,Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT01085617completed Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia · 188 trials list this drug (6 active)	—	—	Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00483366Phase 1 · completed Imatinib Mesylate, Gemcitabine, and Capecitabine in Treating Patients With Advanced Solid Tumors · 188 trials list this drug (6 active)	—	—	Adult Solid Neoplasm	1	Observed	clinicaltrials	graph →

Imatinib Mesylate studied in …STUDIED_INderived10 of 188show all (up to 200)

→ studied in

NCT03516279Phase 2 · active not recruiting

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease · 188 trials list this drug (6 active)

—

Observed

→ studied in

NCT00070499Phase 2 · active not recruiting

Imatinib Mesylate or Dasatinib in Treating Patients With Previously Untreated Chronic Phase Chronic Myelogenous Leukemia · 188 trials list this drug (6 active)

—

Observed

Acute Lymphoblastic Leukemia,B Acute Lymphoblastic Leukemia,T Acute Lymphoblastic Leukemia+1

→ studied in

NCT03007147Phase 3 · active not recruiting

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia · 188 trials list this drug (6 active)

—

Observed

→ studied in

NCT01742299Phase 4 · completed

Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator · 188 trials list this drug (6 active)

—

not mapped

Observed

Gastrointestinal Stromal Tumor,Malignant Gastrointestinal Stromal Tumor

→ studied in

NCT06655246Phase 1 · recruiting

A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) · 188 trials list this drug (6 active)

—

Observed

→ studied in

NCT00015847Phase 2 · terminated

Imatinib Mesylate and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia · 188 trials list this drug (6 active)

—

Observed

Gastrointestinal Stromal Tumor

→ studied in

NCT05385549Phase 2 · recruiting

5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk · 188 trials list this drug (6 active)

—

Observed

Chronic Myeloid Leukemia, BCR-ABL1 Positive,Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive

→ studied in

NCT01751425Phase 1 · terminated

Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase Inhibitors · 188 trials list this drug (6 active)

—

Observed

→ studied in

NCT01085617completed

Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia · 188 trials list this drug (6 active)

—

Observed

→ studied in

NCT00483366Phase 1 · completed

Imatinib Mesylate, Gemcitabine, and Capecitabine in Treating Patients With Advanced Solid Tumors · 188 trials list this drug (6 active)

—

Adult Solid Neoplasm

Observed