| Denosumab studied in …STUDIED_INderived75 of 75show fewer |
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| → studied in | NCT02129699Phase 3 · terminated Survival imProvement in Lung cancEr iNduced by DenOsUmab theRapy · 75 trials list this drug (11 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03839459Phase 2 · completed Denosumab for Smoldering Multiple Myeloma · 75 trials list this drug (11 active) | — | — | Smoldering Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03958565recruiting Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations. · 75 trials list this drug (11 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06374459Phase 1/Phase 2 · recruiting Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis · 75 trials list this drug (11 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07537972Phase 2 · not yet recruiting Denosumab Strategy for Liver Cancer With Bone Metastases · 75 trials list this drug (11 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03869762Phase 2 · terminated Denosumab in Combination With Enzalutamide in Progressive Metastatic Castrate-resistant Prostate Cancer and Bone Metastases. · 75 trials list this drug (11 active) | — | — | Malignant Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03401060Phase 3 · completed Interest of Denosumab Treatment in Osteoporosis Associated to Systemic Mastocytosis · 75 trials list this drug (11 active) | — | — | Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04067726Phase 2 · active not recruiting RANKL Inhibition and Mammographic Breast Density · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03620019Phase 2 · completed Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma · 75 trials list this drug (11 active) | — | — | Melanoma,Cutaneous Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02051218Phase 3 · active not recruiting Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm,Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04586660Phase 4 · active not recruiting Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04907539Phase 2 · completed A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC) · 75 trials list this drug (11 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04711109Phase 3 · active not recruiting Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation · 75 trials list this drug (11 active) | — | — | Neoplasm,Breast Neoplasm,Malignant Breast Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04907851Phase 2 · completed A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) · 75 trials list this drug (11 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03792763Phase 2 · completed Denosumab for High Risk SMM and SLiM CRAB Positive, Early Myeloma Patients · 75 trials list this drug (11 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06749886Phase 2 · recruiting An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting · 75 trials list this drug (11 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03629717early Phase 1 · completed RANKL Inhibition and Breast Tissue Biomarkers · 75 trials list this drug (11 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02613416Phase 2 · completed Denosumab and MRI Breast Imaging · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03301857Phase 4 · completed Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004 · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06314698Phase 3 · not yet recruiting Narlumosbart Compared With Denosumab in Patients With Multiple Myeloma Bone Disease · 75 trials list this drug (11 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02470091Phase 2 · completed Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma · 75 trials list this drug (11 active) | — | — | Osteosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03324932Phase 3 · active not recruiting Efficacy of Denosumab on Normal BMD in Women Receiving Adjuvant Aromatase Inhibitors for Early Breast Cancer · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00556374Phase 3 · completed Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05813665Phase 3 · not yet recruiting A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04812509Phase 3 · completed Efficacy and Safety of MW032 and Xgeva® in Subjects With Bone Metastases From Solid Tumors · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00321464Phase 3 · completed A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects. · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00396279Phase 2 · completed Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone · 75 trials list this drug (11 active) | — | — | Digestive System Neuroendocrine Tumor G1,Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01345019Phase 3 · completed Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma · 75 trials list this drug (11 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Malignant Neoplasm,Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00330759Phase 3 · completed Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma. · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00680992Phase 2 · completed Study of Denosumab in Subjects With Giant Cell Tumor of Bone · 75 trials list this drug (11 active) | — | — | Malignant Neoplasm,Giant Cell Tumor,Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05435768unknown PraG With RANKL Inhibitor for the Treatment of Advanced Multiple Metastatic Solid Tumors · 75 trials list this drug (11 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03382574early Phase 1 · terminated Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy · 75 trials list this drug (11 active) | — | — | Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05402865completed A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03161756Phase 1/Phase 2 · unknown Evaluation of Denosumab in Combination With Immune Checkpoint Inhibitors in Patients With Unresectable or Metastatic Melanoma · 75 trials list this drug (11 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03520231Phase 2 · completed Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases · 75 trials list this drug (11 active) | — | — | Malignant Kidney Neoplasm,Urothelial Carcinoma,Malignant Bladder Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03691311early Phase 1 · unknown Biomarker Study of the Antitumoral Activity of Denosumab in the Pre- Operative Setting of Early Breast Cancer · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01951586Phase 2 · completed Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer · 75 trials list this drug (11 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03408652Phase 3 · terminated Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies · 75 trials list this drug (11 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02366130Phase 2 · completed Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01077154Phase 3 · terminated Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04859569Phase 3 · unknown Efficacy and Safety of LY01011 and Xgeva® in Patients With Bone Metastases From Solid Tumors · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04798326Phase 1 · completed Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults · 75 trials list this drug (11 active) | — | — | Bone Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01624766Phase 1 · completed Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers · 75 trials list this drug (11 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02682693Phase 2 · completed Denosumab as an add-on Neoadjuvant Treatment (GeparX) · 75 trials list this drug (11 active) | — | — | Breast Inflammatory Carcinoma,Breast Mucinous Carcinoma,Breast Tubular Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03620149Phase 2 · terminated Reduced Dose-density of Denosumab for Unresectable GCTB · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02721433Phase 4 · completed 4-weekly Versus 12-weekly Administration of Bone-targeted Agents in Patients With Bone Metastases · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm,Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04550949Phase 3 · unknown To Evaluate the Efficacy and Safety of QL1206 and Xgeva in Patients With Bone Metastases From Solid Tumors · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02900469early Phase 1 · completed Presurgical Trial of Denosumab in Breast Cancer · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04494373Phase 1 · unknown Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03532087Phase 2 · withdrawn Study to Identify the Impact of Denosumab on the Immune System in Patients With HER2 Negative Breast Cancer · 75 trials list this drug (11 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01545648Phase 2 · terminated Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer · 75 trials list this drug (11 active) | — | — | Early Stage Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01952054Phase 2 · terminated Denosumab for Breast Cancer With Bone Mets · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02758132Phase 2 · terminated Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases · 75 trials list this drug (11 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01419717Phase 3 · completed Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03605199Phase 2 · unknown Denosumab in Subjects With Giant Cell Rich Tumors of Bone · 75 trials list this drug (11 active) | — | — | Aneurysmal Bone Cyst,Chondroblastoma,Chondromyxoid Fibroma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01864798Phase 2 · terminated A Study to Evaluate Denosumab in Young Patients With Primary Breast Cancer · 75 trials list this drug (11 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03070002Phase 2 · terminated Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00838201Phase 3 · completed Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer · 75 trials list this drug (11 active) | — | — | Neoplasm,Malignant Neoplasm,Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00089674Phase 3 · completed AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer · 75 trials list this drug (11 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00286091Phase 3 · completed Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00896454Phase 2 · completed Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium · 75 trials list this drug (11 active) | — | — | Malignant Neoplasm,Lymphoma,Malignant Breast Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00980174Phase 3 · completed Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00321620Phase 3 · completed Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03487055Phase 1 · unknown Safety Assessment of Repeated Administration of TK006 in Patients With Breast Cancer-related Bone Metastases · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03415477Phase 1/Phase 2 · completed Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts · 75 trials list this drug (11 active) | — | — | Neoplasm,Aneurysmal Bone Cyst | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03358212unknown Safety and Efficacy of Post-operative Denosumab Strategy for Giant Cell Tumor of Bone Treatment in China · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03259152Phase 3 · unknown Characteristics and Mechanism of Denosumab-treated Giant Cell Tumor of Bone · 75 trials list this drug (11 active) | — | — | Giant Cell Tumor of Bone | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03239756Phase 1 · unknown Assessment of TK006 in Patients With Breast Cancer-related Bone Metastases · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00925600Phase 3 · completed Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss · 75 trials list this drug (11 active) | — | — | Malignant Neoplasm,Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00259740Phase 2 · completed Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab · 75 trials list this drug (11 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01920568Phase 3 · completed A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01824342Phase 3 · completed Denosumab for Prolonging Bone Metastasis-Free Survival in Men With Hormone-Refractory Prostate Cancer · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02101164Phase 4 · withdrawn Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease · 75 trials list this drug (11 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00950911Phase 3 · completed Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only · 75 trials list this drug (11 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00091832Phase 2 · completed Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer · 75 trials list this drug (11 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |