Skip to content

CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Pulse Data updates Year in cancer Taxonomy Countries Compare Trial intelligence Trial map Drug pipeline Sources Methodology About Trust & policies Data downloads Developers (API)

Loading cancer entity…

CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

Every number links to its source and retrieval date. Derived metrics carry a formula version. AI-generated synthesis is not enabled in this phase; all content is database-grounded.

About Trust & policies Data explorer Data downloads Pulse Data update log Developers (API)Sources Methodology Taxonomy Countries Compare Contact · contact@spboucher.ai Status

© 2026 CancerIndex · built and maintained by Simon-Pierre Boucher · contact contact@spboucher.ai · hosted on MacLustr (www.maclustr.io). Source data remains under the license of each provider — see /sources.

WHO Grade 4 Glioma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Nervous System Neoplasm
Central Nervous System Neoplasm
Malignant Central Nervous System Neoplasm
Malignant Glioma
WHO Grade 4 Glioma

Subtype

WHO Grade 4 Glioma

CI-CAN-00007117Explore in graph →

535 active trials3 approved drugs58 evidence items

NCIt: C200758

Overview
Statistics
Survival
Genomics1
Variants & evidence58
Drugs21
Trials1854
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A group of malignant gliomas that includes the following: glioblastoma; diffuse midline glioma; diffuse hemispheric glioma, H3 G34-mutant; astrocytoma, IDH-mutant, grade 4; and diffuse pediatric-type high grade glioma, H3-wildtype and IDH-wildtype.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Malignant GliomaSubtype

Children (6)

ncit

Astrocytoma, IDH-Mutant, Grade 4
Childhood WHO Grade 4 Glioma4 sub
Diffuse Hemispheric Glioma, H3 G34-Mutant2 sub
Diffuse Midline Glioma5 sub
Diffuse Pediatric-Type High Grade Glioma, H3-Wildtype and IDH-Wildtype5 sub
Glioblastoma11 sub

70 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00007117
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 6
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

1,854 / 535

Publications (all / 5y)

3 / 3

Evidence items

58

Genes / variants

100 / 40

Drugs (any / approved)

21 / 3

Genomic cohorts

1

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (0)

Only the preferred name is recorded so far.

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
Active trials535countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #73 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials288countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #74 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items58countaccepted CIViC items · entity + descendantscivicComputedrank #73 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months3countPubMed records · stored query · 12-month windowpubmedComputedrank #1485 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts1countopen GDC projects · entity + descendantsgdcComputedrank #228 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 18 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants