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CancerIndex

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Diffuse Midline Glioma · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
Neuroepithelial Neoplasm
Glioma
Diffuse Glioma
Diffuse Midline Glioma

Subtype

Diffuse Midline Glioma

CI-CAN-00005114Explore in graph →

61 active trials1 approved drugs15 evidence items

NCIt: C182151

Overview
Statistics
Survival
Genomics
Variants & evidence15
Drugs2
Trials129
Research
Rankings
Sources & provenance

Data completeness4 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A diffuse glioma that arises from the midline structures of the central nervous system. The majority of these tumors are found in the brainstem.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Diffuse GliomaSubtype
WHO Grade 4 GliomaSubtype

Children (5)

ncit

Adult Diffuse Midline Glioma2 sub
Childhood Diffuse Midline Glioma2 sub
Diffuse Intrinsic Pontine Glioma2 sub
Diffuse Midline Glioma, H3 K27-Altered5 sub
Diffuse Non-Pontine Midline Glioma

13 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00005114
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 6
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 129 / 61

Publications (all / 5y)

871 / 732

Evidence items

15

Genes / variants

4 / 10

Drugs (any / approved)

2 / 1

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (0)

Only the preferred name is recorded so far.

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
Active trials61countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #255 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials32countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #253 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items15countaccepted CIViC items · entity + descendantscivicComputedrank #170 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months202countPubMed records · stored query · 12-month windowpubmedComputedrank #233 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants