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CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

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CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

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Malignant Glioma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Nervous System Neoplasm
Central Nervous System Neoplasm
Malignant Central Nervous System Neoplasm
Malignant Glioma

Subtype

Malignant Glioma

CI-CAN-00003164Explore in graph →

589 active trials3 approved drugs67 evidence items

NCIt: C4822

Overview
Statistics
Survival
Genomics1
Variants & evidence67
Drugs22
Trials2053
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A grade 3 or grade 4 glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

GliomaSubtype
Malignant Central Nervous System NeoplasmCancer

Children (6)

ncit

Childhood Malignant Glioma3 sub
High Grade Astrocytic Tumor3 sub
Malignant Brain Glioma11 sub
Meningeal Gliomatosis
WHO Grade 3 Glioma7 sub
WHO Grade 4 Glioma6 sub

114 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00003164
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 5
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

2,053 / 589

Publications (all / 5y)

11,108 / 3,033

Evidence items

67

Genes / variants

100 / 42

Drugs (any / approved)

22 / 3

Genomic cohorts

1

Epidemiology / survival obs.

0 / 0

Data updated 19 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (7)

GLIOMA, MALIGNANTsynonym · NCIt
High Grade Gliomasynonym · NCIt
Malignant Glial Neoplasmsynonym · NCIt
Malignant Glial Tumorsynonym · NCIt
Malignant Gliomasynonym · CIViC
Malignant Neuroglial Neoplasmsynonym · NCIt
Malignant Neuroglial Tumorsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
Active trials589countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #66 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials316countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #64 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items67countaccepted CIViC items · entity + descendantscivicComputedrank #61 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months576countPubMed records · stored query · 12-month windowpubmedComputedrank #132 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts1countopen GDC projects · entity + descendantsgdcComputedrank #228 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 19 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants