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CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

Every number links to its source and retrieval date. Derived metrics carry a formula version. AI-generated synthesis is not enabled in this phase; all content is database-grounded.

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Malignant Central Nervous System Neoplasm · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Nervous System Neoplasm
Central Nervous System Neoplasm
Malignant Central Nervous System Neoplasm

Cancer

Malignant Central Nervous System Neoplasm

CI-CAN-00001115Explore in graph →

Top-level823 active trials5 approved drugs103 evidence items

NCIt: C4627
ICD-10: C70-C72

Overview
Statistics369
Survival
Genomics10
Variants & evidence103
Drugs25
Trials2864
Research
Rankings
Sources & provenance

Data completeness6 / 7 dimensions

Epidemiology (data present)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A primary or metastatic malignant neoplasm involving the brain or spinal cord. Representative examples include anaplastic astrocytoma, glioblastoma, anaplastic (malignant) meningioma, lymphoma, and metastatic carcinoma from another anatomic site.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Central Nervous System NeoplasmCancer Family
Malignant Nervous System NeoplasmCancer Family

Children (16)

ncit

Anaplastic Ganglioglioma
Central Nervous System Carcinoma2 sub
Central Nervous System Embryonal Tumor12 sub
Central Nervous System Ganglioneuroblastoma1 sub
Central Nervous System Histiocytic Sarcoma
Central Nervous System Leukemia1 sub
Central Nervous System Lymphoma6 sub

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00001115
Entity type: Cancer
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

Central Nervous System Multiple Myeloma

Childhood Malignant Central Nervous System Neoplasm13 sub

Malignant Central Nervous System Germ Cell Tumor7 sub

Malignant Central Nervous System Mesenchymal, Non-Meningothelial Neoplasm2 sub

Malignant Glioma6 sub

Malignant Intracranial Neoplasm3 sub

Malignant Meningeal Neoplasm7 sub

Malignant Spinal Cord Neoplasm7 sub

Retinoblastoma9 sub

384 descendants in total; counters on this page aggregate over all of them.

2,864 / 823

Publications (all / 5y)

645 / 298

Evidence items

103

Genes / variants

111 / 62

Drugs (any / approved)

25 / 5

Genomic cohorts

10

Epidemiology / survival obs.

369 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (21)

Brain and Central Nervous System Cancerdisplay · CancerIndex top-level set
Cancer of Central Nervous Systemsynonym · NCIt
Cancer of CNSsynonym · NCIt
Cancer of the Central Nervous Systemsynonym · NCIt
Cancer of the CNSsynonym · NCIt
Central Nervous System Cancersynonym · NCIt
Central Nervous System Neoplasms, Malignantsynonym · NCIt
CNS Cancersynonym · NCIt
CNS Malignant Neoplasmssynonym · NCIt
CNS Neoplasms, Malignantsynonym · NCIt
Malignant Central Nervous System Tumorsynonym · NCIt
Malignant CNS Neoplasmsynonym · NCIt
Malignant CNS Tumorsynonym · NCIt
Malignant Neoplasm of Central Nervous Systemsynonym · NCIt
Malignant Neoplasm of CNSsynonym · NCIt
Malignant Neoplasm of the Central Nervous Systemsynonym · NCIt
Malignant Neoplasm of the CNSsynonym · NCIt
Malignant Tumor of Central Nervous Systemsynonym · NCIt
Malignant Tumor of CNSsynonym · NCIt
Malignant Tumor of the Central Nervous Systemsynonym · NCIt
Malignant Tumor of the CNSsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)
Active trials823countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #8 of 36 (World · both sexes · all ages · latest · top-level cancers)
Recruiting trials453countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #8 of 36 (World · both sexes · all ages · latest · top-level cancers)
Curated evidence items103countaccepted CIViC items · entity + descendantscivicComputedrank #4 of 28 (World · both sexes · all ages · latest · top-level cancers)
Publications, last 12 months61countPubMed records · stored query · 12-month windowpubmedComputedrank #35 of 36 (World · both sexes · all ages · latest · top-level cancers)
Genomic cohorts10countopen GDC projects · entity + descendantsgdcComputedrank #12 of 27 (World · both sexes · all ages · latest · top-level cancers)

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants