Ocular Melanoma — Genomics

Ocular Melanoma — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

5 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Uveal Melanoma TCGA-UVMTCGA

80 cases with simple somatic mutation data · 80 cases total · Data Release 46.0 · mapped to Uveal Melanoma ONTOLOGY_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	CCN4	Ssm	62	80	77.5%	gdc
2	SLC45A4	Ssm	61	80	76.3%	gdc
3	GRHL2	Ssm	60	80	75%	gdc
4	NDRG1	Ssm	60	80	75%	gdc
5	AGO2	Ssm	60	80	75%	gdc
6	MTBP	Ssm	60	80	75%	gdc
7	DEPTOR	Ssm	60	80	75%	gdc
8	EFR3A	Ssm	60

Data updated 22 days agoSource updated Data Release 46.0

Uveal Melanoma (QIMR, Oncotarget 2016) um_qimr_2016QIMR

26 cases with simple somatic mutation data · 28 cases total · 2026-01-16 · mapped to Uveal Melanoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GNA11	Ssm

Uveal Melanoma (TCGA, Firehose Legacy) uvm_tcgaTCGA

80 cases with simple somatic mutation data · 80 cases total · 2026-01-13 · mapped to Uveal Melanoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GNAQ	Ssm	40	80	50%

Uveal Melanoma (TCGA GDC, 2025) um_tcga_gdcTCGA GDC

80 cases with simple somatic mutation data · 80 cases total · 2026-01-14 · mapped to Uveal Melanoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GNAQ	Ssm	39	80	48.8%

Uveal Melanoma (TCGA, PanCancer Atlas) uvm_tcga_pan_can_atlas_2018TCGA

80 cases with simple somatic mutation data · 80 cases total · 2026-06-05 · mapped to Uveal Melanoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GNAQ

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.