Nerve Sheath Neoplasm — Genomics

Nerve Sheath Neoplasm — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

4 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021) nfib_ctf_biobank_2025CTF

38 cases with simple somatic mutation data · 38 cases total · 2026-03-05 · mapped to Neurofibroma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TTN	Ssm	18	38	47.4%	cbioportal
2	ADGRV1	Ssm	12	38	31.6%	cbioportal
4	NF1	Ssm	11	38	28.9%	cbioportal
3	DST	Ssm	11	38	28.9%	cbioportal
6	CPD	Ssm	9	38	23.7%	cbioportal
11	UNC80	Ssm	9	38	23.7%	cbioportal
10	PRKDC	Ssm	9	38	23.7%	cbioportal
9	MUC19

Data updated 22 days agoSource updated 2026-03-05

Malignant Peripheral Nerve Sheath Tumor (MSK, Nat Genet 2014) mpnst_mskccMSK

15 cases with simple somatic mutation data · 15 cases total · 2026-01-08 · mapped to Malignant Peripheral Nerve Sheath Tumor EXACT_IDENTIFIER

cbioportalObserved19 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	EED

Nerve Sheath Tumors (Johns Hopkins, 2024) nst_nfosi_ntapJohns Hopkins

80 cases with simple somatic mutation data · 134 cases total · 2026-01-12 · mapped to Nerve Sheath Neoplasm EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	NF1	Ssm

Schwannoma (Children's Tumor Foundation, Acta Neuropathologica 2020) schw_ctf_synodos_2025Children's Tumor Foundation

40 cases with simple somatic mutation data · 52 cases total · 2026-01-13 · mapped to Schwannoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	NF2

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.