Gene
ANKRD12
ankyrin repeat domain 12
Explore in graph →CI-GENE-00010789HGNC:29135 ENSG00000101745 NCBI 23253 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (24)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33585982
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021) nfib_ctf_biobank_2025 | Neurofibroma | Ssm | 8 | 38 | 21.1% | 13 | cbioportal |
| Metastatic Breast Cancer (AURORA US Network, Nat Cancer 2023) brca_aurora_2023 | Invasive Breast Carcinoma | Ssm | 16 | 134 | 11.9% | 77 | cbioportal |
| Liver Hepatocellular Carcinoma (TCGA, Firehose Legacy) lihc_tcga | Hepatocellular Carcinoma | Ssm | 19 | 373 | 5.1% | 55 | cbioportal |
| Combined Hepatocellular and Intrahepatic Cholangiocarcinoma (Peking University, Cancer Cell 2019) hccihch_pku_2019 | Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Ssm | 8 | 173 | 4.6% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.