Cancer Family
Neoplasm
CI-CAN-00000001Explore in graph →
Non-malignant22,950 active trials259 approved drugs4,031 evidence items
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Cancer Family
CI-CAN-00000001Explore in graph →
Genomics
495 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
60 cases with simple somatic mutation data · 63 cases total · Data Release 46.0 · mapped to Malignant Prostate Neoplasm CURATED_BROADER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | TP53 | Ssm | 17 | 60 | 28.3% | gdc |
| 2 | RIMS2 | Ssm | 9 | 60 | 15% | gdc |
| 3 | SPOP | Ssm | 8 | 60 | 13.3% | gdc |
| 4 | FOXA1 | Ssm | 8 | 60 | 13.3% | gdc |
| 5 | TTN | Ssm | 7 | 60 | 11.7% | gdc |
| 7 | PTEN | Ssm | 5 | 60 | 8.3% | gdc |
| 8 | HMCN1 | Ssm | 5 | 60 | 8.3% | gdc |
| 6 | XIAP | Ssm | 5 | 60 | 8.3% | gdc |
| 10 | FAM161A | Ssm | 5 | 60 | 8.3% | gdc |
| 9 | XPO5 | Ssm | 5 | 60 | 8.3% | gdc |
| 19 | MGA | Ssm | 4 | 60 | 6.7% | gdc |
| 17 | MUC16 | Ssm | 4 | 60 | 6.7% | gdc |
| 20 | OBSCN | Ssm | 4 | 60 | 6.7% | gdc |
| 16 | DCHS2 | Ssm | 4 | 60 | 6.7% | gdc |
| 18 | KMT2D | Ssm | 4 | 60 | 6.7% | gdc |
| 12 | DNAH17 | Ssm | 4 | 60 | 6.7% | gdc |
| 21 | NOTCH1 | Ssm | 4 | 60 | 6.7% | gdc |
| 13 | DNAH3 | Ssm | 4 | 60 | 6.7% | gdc |
| 14 | TYK2 | Ssm | 4 | 60 | 6.7% | gdc |
| 15 | MUC4 | Ssm | 4 | 60 | 6.7% | gdc |
| 11 | SDK1 | Ssm | 4 | 60 | 6.7% | gdc |
| 32 | KMT2A | Ssm | 3 | 60 | 5% | gdc |
| 42 | KNDC1 | Ssm | 3 | 60 | 5% | gdc |
| 46 | MAP4K1 | Ssm | 3 | 60 | 5% | gdc |
| 49 | MATR3 | Ssm | 3 | 60 | 5% | gdc |
| 57 | MEIS2 | Ssm | 3 | 60 | 5% | gdc |
| 39 | ZFHX4 | Ssm | 3 | 60 | 5% | gdc |
| 67 | ADRA1A | Ssm | 3 | 60 | 5% | gdc |
| 22 | ANAPC5 | Ssm | 3 | 60 | 5% | gdc |
| 64 | ATP2B2 | Ssm | 3 | 60 | 5% | gdc |
Data updated 22 days agoSource updated Data Release 46.0