Cancer Family
Neoplasm
CI-CAN-00000001Explore in graph →
Non-malignant22,950 active trials259 approved drugs4,031 evidence items
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Cancer Family
CI-CAN-00000001Explore in graph →
Genomics
495 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
412 cases with simple somatic mutation data · 413 cases total · 2026-01-05 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 2 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 198 |
| 412 |
| 48.1% |
| cbioportal |
| 1 | TP53 | Ssm | 198 | 412 | 48.1% | cbioportal |
| 4 | MUC16 | Ssm | 117 | 412 | 28.4% | cbioportal |
| 3 | KMT2D | Ssm | 117 | 412 | 28.4% | cbioportal |
| 5 | KDM6A | Ssm | 107 | 412 | 26% | cbioportal |
| 6 | ARID1A | Ssm | 101 | 412 | 24.5% | cbioportal |
| 7 | PIK3CA | Ssm | 91 | 412 | 22.1% | cbioportal |
| 8 | SYNE1 | Ssm | 84 | 412 | 20.4% | cbioportal |
| 9 | RYR2 | Ssm | 78 | 412 | 18.9% | cbioportal |
| 10 | KMT2C | Ssm | 77 | 412 | 18.7% | cbioportal |
| 11 | HMCN1 | Ssm | 76 | 412 | 18.4% | cbioportal |
| 12 | RB1 | Ssm | 72 | 412 | 17.5% | cbioportal |
| 13 | FLG | Ssm | 68 | 412 | 16.5% | cbioportal |
| 14 | MACF1 | Ssm | 66 | 412 | 16% | cbioportal |
| 15 | EP300 | Ssm | 63 | 412 | 15.3% | cbioportal |
| 16 | FAT4 | Ssm | 63 | 412 | 15.3% | cbioportal |
| 17 | FGFR3 | Ssm | 58 | 412 | 14.1% | cbioportal |
| 20 | STAG2 | Ssm | 57 | 412 | 13.8% | cbioportal |
| 19 | CSMD3 | Ssm | 57 | 412 | 13.8% | cbioportal |
| 18 | ATM | Ssm | 57 | 412 | 13.8% | cbioportal |
| 21 | NEB | Ssm | 56 | 412 | 13.6% | cbioportal |
| 22 | OBSCN | Ssm | 56 | 412 | 13.6% | cbioportal |
| 23 | DNAH5 | Ssm | 54 | 412 | 13.1% | cbioportal |
| 24 | DNAH11 | Ssm | 53 | 412 | 12.9% | cbioportal |
| 26 | SYNE2 | Ssm | 52 | 412 | 12.6% | cbioportal |
| 25 | CUBN | Ssm | 52 | 412 | 12.6% | cbioportal |
| 28 | FAT1 | Ssm | 51 | 412 | 12.4% | cbioportal |
| 27 | BIRC6 | Ssm | 51 | 412 | 12.4% | cbioportal |
| 33 | RYR1 | Ssm | 50 | 412 | 12.1% | cbioportal |
| 32 | ERBB2 | Ssm | 50 | 412 | 12.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05