Cancer Family
Neoplasm
CI-CAN-00000001Explore in graph →
Non-malignant22,950 active trials259 approved drugs4,031 evidence items
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Cancer Family
CI-CAN-00000001Explore in graph →
Genomics
495 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
25 cases with simple somatic mutation data · 31 cases total · 2026-02-11 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 18 |
| 25 |
| 72% |
| cbioportal |
| 2 | TTN | Ssm | 7 | 25 | 28% | cbioportal |
| 7 | RYR2 | Ssm | 6 | 25 | 24% | cbioportal |
| 8 | SPTA1 | Ssm | 6 | 25 | 24% | cbioportal |
| 6 | OBSCN | Ssm | 6 | 25 | 24% | cbioportal |
| 3 | DST | Ssm | 6 | 25 | 24% | cbioportal |
| 5 | LAMA5 | Ssm | 6 | 25 | 24% | cbioportal |
| 4 | FAT1 | Ssm | 6 | 25 | 24% | cbioportal |
| 13 | PLEC | Ssm | 5 | 25 | 20% | cbioportal |
| 16 | SYNE1 | Ssm | 5 | 25 | 20% | cbioportal |
| 10 | FASN | Ssm | 5 | 25 | 20% | cbioportal |
| 14 | RYR1 | Ssm | 5 | 25 | 20% | cbioportal |
| 9 | AEBP1 | Ssm | 5 | 25 | 20% | cbioportal |
| 11 | PAPPA2 | Ssm | 5 | 25 | 20% | cbioportal |
| 15 | SRCAP | Ssm | 5 | 25 | 20% | cbioportal |
| 12 | PKHD1L1 | Ssm | 5 | 25 | 20% | cbioportal |
| 40 | PRKDC | Ssm | 4 | 25 | 16% | cbioportal |
| 32 | LRP2 | Ssm | 4 | 25 | 16% | cbioportal |
| 48 | UBR5 | Ssm | 4 | 25 | 16% | cbioportal |
| 27 | FGFR3 | Ssm | 4 | 25 | 16% | cbioportal |
| 33 | MAG | Ssm | 4 | 25 | 16% | cbioportal |
| 49 | VPS13B | Ssm | 4 | 25 | 16% | cbioportal |
| 19 | ATP2B1 | Ssm | 4 | 25 | 16% | cbioportal |
| 41 | REV3L | Ssm | 4 | 25 | 16% | cbioportal |
| 17 | ADGRG5 | Ssm | 4 | 25 | 16% | cbioportal |
| 28 | GOLGA2 | Ssm | 4 | 25 | 16% | cbioportal |
| 42 | RYR3 | Ssm | 4 | 25 | 16% | cbioportal |
| 35 | MTCL1 | Ssm | 4 | 25 | 16% | cbioportal |
| 43 | SCAPER | Ssm | 4 | 25 | 16% | cbioportal |
| 23 | CUX2 | Ssm | 4 | 25 | 16% | cbioportal |
Data updated 21 days agoSource updated 2026-02-11