Cancer
Neoplasm of Uncertain Histogenesis
CI-CAN-00000034Explore in graph →
Non-malignant20,272 active trials259 approved drugs3,813 evidence items
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Cancer
CI-CAN-00000034Explore in graph →
Genomics
465 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
10 cases with simple somatic mutation data · 19 cases total · 2026-01-12 · mapped to Primary Central Nervous System Lymphoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| MYD88 |
| Ssm |
| 7 |
| 10 |
| 70% |
| cbioportal |
| 5 | SMG5 | Ssm | 4 | 10 | 40% | cbioportal |
| 4 | PIM1 | Ssm | 4 | 10 | 40% | cbioportal |
| 3 | DLGAP2 | Ssm | 4 | 10 | 40% | cbioportal |
| 2 | CD79B | Ssm | 4 | 10 | 40% | cbioportal |
| 11 | KLHL14 | Ssm | 3 | 10 | 30% | cbioportal |
| 10 | FAT4 | Ssm | 3 | 10 | 30% | cbioportal |
| 9 | DST | Ssm | 3 | 10 | 30% | cbioportal |
| 8 | DSG4 | Ssm | 3 | 10 | 30% | cbioportal |
| 6 | BTG2 | Ssm | 3 | 10 | 30% | cbioportal |
| 7 | CARD11 | Ssm | 3 | 10 | 30% | cbioportal |
| 15 | TENM1 | Ssm | 3 | 10 | 30% | cbioportal |
| 14 | TCL1A | Ssm | 3 | 10 | 30% | cbioportal |
| 13 | PRR12 | Ssm | 3 | 10 | 30% | cbioportal |
| 12 | LRP1B | Ssm | 3 | 10 | 30% | cbioportal |
| 108 | ZNF831 | Ssm | 2 | 10 | 20% | cbioportal |
| 17 | AHNAK | Ssm | 2 | 10 | 20% | cbioportal |
| 18 | ANGPTL6 | Ssm | 2 | 10 | 20% | cbioportal |
| 19 | APBA1 | Ssm | 2 | 10 | 20% | cbioportal |
| 20 | ARAF | Ssm | 2 | 10 | 20% | cbioportal |
| 21 | BCL2 | Ssm | 2 | 10 | 20% | cbioportal |
| 22 | BSN | Ssm | 2 | 10 | 20% | cbioportal |
| 23 | BTG1 | Ssm | 2 | 10 | 20% | cbioportal |
| 24 | C10ORF71 | Ssm | 2 | 10 | 20% | cbioportal |
| 25 | CCDC7 | Ssm | 2 | 10 | 20% | cbioportal |
| 26 | CDKN1B | Ssm | 2 | 10 | 20% | cbioportal |
| 27 | CEP295 | Ssm | 2 | 10 | 20% | cbioportal |
| 28 | CFAP47 | Ssm | 2 | 10 | 20% | cbioportal |
| 29 | CHPF2 | Ssm | 2 | 10 | 20% | cbioportal |
| 30 | CNTNAP5 | Ssm | 2 | 10 | 20% | cbioportal |
Data updated 22 days agoSource updated 2026-01-12