Cancer
Neoplasm of Uncertain Histogenesis
CI-CAN-00000034Explore in graph →
Non-malignant20,272 active trials259 approved drugs3,813 evidence items
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Cancer
CI-CAN-00000034Explore in graph →
Genomics
465 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
470 cases with simple somatic mutation data · 470 cases total · Data Release 46.0 · mapped to Cutaneous Melanoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 388 |
| 470 |
| 82.6% |
| gdc |
| 2 | MUC16 | Ssm | 377 | 470 | 80.2% | gdc |
| 3 | ANK3 | Ssm | 375 | 470 | 79.8% | gdc |
| 4 | CDKN2A | Ssm | 361 | 470 | 76.8% | gdc |
| 5 | PTPRD | Ssm | 360 | 470 | 76.6% | gdc |
| 6 | CDKN2B | Ssm | 356 | 470 | 75.7% | gdc |
| 7 | AL359922.1 | Ssm | 354 | 470 | 75.3% | gdc |
| 8 | FREM1 | Ssm | 352 | 470 | 74.9% | gdc |
| 9 | DMBT1 | Ssm | 352 | 470 | 74.9% | gdc |
| 10 | MTAP | Ssm | 351 | 470 | 74.7% | gdc |
| 11 | DNAH5 | Ssm | 350 | 470 | 74.5% | gdc |
| 12 | DMRTA1 | Ssm | 346 | 470 | 73.6% | gdc |
| 14 | PCLO | Ssm | 342 | 470 | 72.8% | gdc |
| 13 | TAF1L | Ssm | 342 | 470 | 72.8% | gdc |
| 15 | IFNE | Ssm | 341 | 470 | 72.6% | gdc |
| 17 | SYNE1 | Ssm | 341 | 470 | 72.6% | gdc |
| 16 | IFNA16 | Ssm | 341 | 470 | 72.6% | gdc |
| 18 | ADAMTSL1 | Ssm | 341 | 470 | 72.6% | gdc |
| 19 | IFNA7 | Ssm | 340 | 470 | 72.3% | gdc |
| 23 | IFNA14 | Ssm | 339 | 470 | 72.1% | gdc |
| 20 | PCDH15 | Ssm | 339 | 470 | 72.1% | gdc |
| 21 | IFNA4 | Ssm | 339 | 470 | 72.1% | gdc |
| 22 | MGAM | Ssm | 339 | 470 | 72.1% | gdc |
| 24 | ELAVL2 | Ssm | 338 | 470 | 71.9% | gdc |
| 27 | IFNA21 | Ssm | 338 | 470 | 71.9% | gdc |
| 26 | FOCAD | Ssm | 338 | 470 | 71.9% | gdc |
| 25 | IFNA6 | Ssm | 338 | 470 | 71.9% | gdc |
| 28 | BNC2 | Ssm | 338 | 470 | 71.9% | gdc |
| 29 | SH3GL2 | Ssm | 337 | 470 | 71.7% | gdc |
| 30 | IFNW1 | Ssm | 336 | 470 | 71.5% | gdc |
Data updated 23 days agoSource updated Data Release 46.0