Gene
TCL1A
TCL1 family AKT coactivator A
Explore in graph →CI-GENE-00034787HGNC:11648 ENSG00000100721 NCBI 8115 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25991819
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Primary Central Nervous System Lymphoma (Mayo Clinic, Clin Cancer Res 2015) pcnsl_mayo_2015 | Primary Central Nervous System Lymphoma | Ssm | 3 | 10 | 30% | 14 | cbioportal |
| Mature B-Cell Neoplasms (Simon Fraser University, Blood 2023) mbn_sfu_2023 | B-Cell Non-Hodgkin Lymphoma | Ssm | 17 | 297 | 5.7% | 113 | cbioportal |
| Diffuse Large B-Cell Lymphoma (Duke, Cell 2017) dlbcl_duke_2017 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 16 | 1,001 | 1.6% | 128 | cbioportal |
| Chronic Lymphocytic Leukemia (IUOPA, Nature 2015) cll_iuopa_2015 | Small Lymphocytic Lymphoma | Ssm | 5 | 506 | 1% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.