Cancer
Malignant Rectal Neoplasm
CI-CAN-00008012Explore in graph →
Top-level388 active trials1 approved drugs5 evidence items
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Cancer
CI-CAN-00008012Explore in graph →
Clinical trials
1,551 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (153)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05999227 | 68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy | unknown | N/A | 20 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Aug 21, 2023 | clinicaltrials |
| NCT03619668 | Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment(AMPERE) | unknown | — | 16 | Aalborg University Hospital |
| 1 |
| Aug 3, 2023 |
| clinicaltrials |
| NCT05911789 | Online Adaptive Radiation Therapy for Rectal Cancer | unknown | Phase 1 / Phase 2 | 15 | Peking Union Medical College HospitalOTHER | 0 | Aug 1, 2023 | clinicaltrials |
| NCT05969938 | Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology | unknown | — | 50 | WeiWei XiaoOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05877573 | Toripalimab Combined With Neoadjuvant Chemoradiotherapy as First-line Treatment for Locally Advanced，High-Risk，MSS Rectal Cancer | unknown | N/A | 53 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jul 5, 2023 | clinicaltrials |
| NCT05920928 | Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer(TEHRAN) | unknown | N/A | 114 | Tehran University of Medical SciencesOTHER | 0 | Jun 27, 2023 | clinicaltrials |
| NCT05374044 | Establishment of MRI Model for pTRG in Rectal Cancer With Establishment of | unknown | — | 385 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT05910099 | Taking a Look at Patient Experiences In Rectal Cancer Clinical Trials | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Jun 18, 2023 | clinicaltrials |
| NCT04083365 | Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer(PANDORA) | unknown | Phase 2 | 100 | AUSL Romagna RiminiOTHER | 1 | May 31, 2023 | clinicaltrials |
| NCT05243771 | Norwegian Stoma Trial | unknown | — | 400 | The Hospital of VestfoldOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT05873621 | Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant Chemoradiotherapy((GreenEye-CRC)) | unknown | N/A | 60 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT05868317 | Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal Cancer | unknown | Phase 2 | 70 | Salah Azaïz Cancer InstituteOTHER | 1 | May 22, 2023 | clinicaltrials |
| NCT05858567 | Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma(RECMULRA-TNT) | unknown | Phase 2 | 30 | Sir Run Run Shaw HospitalOTHER | 1 | May 15, 2023 | clinicaltrials |
| NCT03699761 | The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection | unknown | N/A | 1,000 | Southwest Hospital, ChinaOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05845268 | Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer | unknown | Phase 2 | 102 | Beijing Friendship HospitalOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05830890 | Sentinel Lymph Node Biopsy in Rectal Cancer | unknown | N/A | 87 | National Cancer Center, ChinaOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT05815303 | XELOX Combined With Cadonilimab Versus XELOX as Neoadjuvant Treatment for Locally Advanced, pMMR Rectal Cancer | unknown | Phase 2 | 92 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05245565 | Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer | unknown | — | 120 | Shanghai 10th People's HospitalOTHER | 1 | Apr 13, 2023 | clinicaltrials |
| NCT05516641 | Prebiotics in Rectal Cancer | unknown | N/A | 20 | Ochsner Health SystemOTHER | 1 | Mar 31, 2023 | clinicaltrials |
| NCT03038256 | Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial(EXPLORE) | unknown | Phase 2 | 244 | Peking University People's HospitalOTHER | 1 | Mar 22, 2023 | clinicaltrials |
| NCT05263336 | Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum | unknown | N/A | 180 | Jagiellonian UniversityOTHER | 1 | Mar 14, 2023 | clinicaltrials |
| NCT05759741 | Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy | unknown | Early Phase 1 | 64 | Huashan HospitalOTHER | 1 | Mar 14, 2023 | clinicaltrials |
| NCT05763927 | Neoadjuvant Therapy for Locally Advanced Rectal Cancer With Fruquintinib, Toripalimab and SRT | unknown | Phase 2 | 44 | West China HospitalOTHER | 1 | Mar 10, 2023 | clinicaltrials |
| NCT05185557 | BRIANSTORM - Early Identification of Patients With Brain Metastases | unknown | — | 50 | Aarhus University HospitalOTHER | 1 | Feb 3, 2023 | clinicaltrials |
| NCT05688033 | Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During Chemoradiotherapy | unknown | N/A | 200 | Fudan UniversityOTHER | 1 | Jan 18, 2023 | clinicaltrials |
| NCT05685680 | Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma | unknown | N/A | 50 | Sohag UniversityOTHER | 1 | Jan 17, 2023 | clinicaltrials |
| NCT05683795 | PelvEx - Beating the Empty Pelvis Syndrome | unknown | — | 150 | University of SouthamptonOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT05664607 | Sarcopenia and Multimodal Rehabilitation on the Prognosis of Rectal Cancer Patients Receiving CCRT | unknown | N/A | 100 | Chang Gung Memorial HospitalOTHER | 1 | Dec 29, 2022 | clinicaltrials |
| NCT05651971 | The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery | unknown | — | 120 | Tang-Du HospitalOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT05645094 | Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer | unknown | — | 38 | Fudan UniversityOTHER | 0 | Dec 13, 2022 | clinicaltrials |
| NCT05640726 | The First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard Therapy | unknown | Phase 2 | 30 | Fujian Cancer HospitalOTHER_GOV | 0 | Dec 7, 2022 | clinicaltrials |
| NCT04991090 | Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study | unknown | N/A | 78 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Nov 23, 2022 | clinicaltrials |
| NCT05359406 | A Combination Therapy Including Anti-PD-1 Immunotherapy in Rectal Cancer With Refractory Distal Metastasis(Miracle-2) | unknown | Phase 2 | 51 | LI XIN-XIANGOTHER | 1 | Nov 15, 2022 | clinicaltrials |
| NCT05336643 | Radioisotope and Fluorescence Guidance in Rectal Cancer | unknown | N/A | 10 | University College, LondonOTHER | 1 | Nov 1, 2022 | clinicaltrials |
| NCT04278274 | Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal Cancer(MR-AI-pCR) | unknown | — | 205 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT05575635 | Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC | unknown | Phase 2 | 40 | Henan Provincial People's HospitalOTHER | 0 | Oct 12, 2022 | clinicaltrials |
| NCT05027737 | Early Ileostomy Closure for Rectal Cancer Patients in North America | unknown | N/A | 118 | Jewish General HospitalOTHER | 1 | Aug 23, 2022 | clinicaltrials |
| NCT04966819 | Rectal Cancer Shared Care | unknown | N/A | 80 | Jewish General HospitalOTHER | 1 | Aug 19, 2022 | clinicaltrials |
| NCT04598984 | The Role of Serum Adipokines in Predicting Response to Neoadjuvant Therapy in Patients With Rectal Cancer | unknown | — | 60 | Istanbul Training and Research HospitalOTHER_GOV | 1 | Aug 8, 2022 | clinicaltrials |
| NCT04857203 | The Role of Vitamin D in Predicting Response to Neoadjuvant Therapy in Patients With Rectal Cancer | unknown | — | 60 | Istanbul Training and Research HospitalOTHER_GOV | 1 | Aug 8, 2022 | clinicaltrials |
| NCT05411783 | Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial(LOTHVEIN) | unknown | N/A | 84 | San Carlo di Nancy HospitalOTHER | 1 | Jun 9, 2022 | clinicaltrials |
| NCT05154474 | Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy(SPACE2) | unknown | — | 150 | WepromOTHER | 1 | May 3, 2022 | clinicaltrials |
| NCT02140723 | p53 and Response to Preoperative Radiotherapy for T2 and T3(PART1) | unknown | — | 60 | Medical University of ViennaOTHER | 1 | Apr 7, 2022 | clinicaltrials |
| NCT03957733 | Phase II/III Study to Assess the Efficacy of Neoadjuvant Consolidation Chemotherapy in Rectal Cancer Patients. | unknown | Phase 2 / Phase 3 | 338 | King Abdullah Medical CityOTHER_GOV | 1 | Apr 6, 2022 | clinicaltrials |
| NCT05302557 | Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial.(Ileostim) | unknown | N/A | 68 | Universidad de LeónOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT02817126 | Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer(REAL) | unknown | N/A | 1,240 | Fudan UniversityOTHER | 1 | Mar 22, 2022 | clinicaltrials |
| NCT05286086 | Prehabilitation in Rectal Cancer: During Neoadjuvant Therapy vs Preoperative(PREHAREC) | unknown | N/A | 50 | Corporacion Parc TauliOTHER | 1 | Mar 18, 2022 | clinicaltrials |
| NCT05284864 | Timing Evaluation of Stoma Closure (TIMES). Early vs Late Closure of Stoma After Rectal Cancer Surgery.(TIMES) | unknown | N/A | 150 | Hospital Universitario La FeOTHER | 1 | Mar 17, 2022 | clinicaltrials |
| NCT04167436 | Fit for Surgery. Multimodal Prehabilitation in Colorectal Cancer Patients | unknown | Phase 2 / Phase 3 | 48 | Zealand University HospitalOTHER | 1 | Mar 3, 2022 | clinicaltrials |
| NCT05241574 | Planned Non-operative Management for Rectal Cancer | unknown | Phase 2 | 23 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Feb 15, 2022 | clinicaltrials |
Data updated 22 days agoSource updated Aug 21, 2023source: clinicaltrials