Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,431 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,448 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07635420 | Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial)(VISION) | recruiting | Phase 4 | 244 | Region SkaneOTHER | 1 | Sep 29, 2026 | clinicaltrials |
| NCT07633613 | Pharmacokinetic Study of Pembrolizumab and Its Impact on Immunity and the Tumor Microenvironment, Which May Explain the Efficacy of Post-immunotherapy Chemotherapy.(CPI) | not yet recruiting | Phase 4 | 110 | Centre Antoine Lacassagne |
| 0 |
| Sep 15, 2026 |
| clinicaltrials |
| NCT07704658 | Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors | recruiting | Phase 4 | 12 | Rigel PharmaceuticalsINDUSTRY | 1 | Aug 10, 2026 | clinicaltrials |
| NCT00333099 | INEC Study: Immuno-modulating Enteral Nutrition in Cancer | completed | Phase 4 | 250 | University Hospital, Clermont-FerrandOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT07697287 | Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment(TOPHAT) | active not recruiting | Phase 4 | 29 | McMaster UniversityOTHER | 1 | Jul 13, 2026 | clinicaltrials |
| NCT04246697 | Multimodal Pain Study in Free Flap Patients | completed | Phase 4 | 30 | University of Kansas Medical CenterOTHER | 1 | Jul 7, 2026 | clinicaltrials |
| NCT07600580 | The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response | recruiting | Phase 4 | 48 | University Hospital DubravaOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT07405086 | Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study | recruiting | Phase 4 | 160 | OHSU Knight Cancer InstituteOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06162377 | Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study. | recruiting | Phase 4 | 25 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT04265430 | Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors | recruiting | Phase 4 | 425 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT07354698 | Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery(MHI) | not yet recruiting | Phase 4 | 114 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07189897 | Apixaban or Enoxaparin After Head and Neck Cancer Surgery | recruiting | Phase 4 | 76 | Kiranya ArnoldOTHER | 1 | Oct 8, 2025 | clinicaltrials |
| NCT01496313 | To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer | completed | Phase 4 | 81 | SanofiINDUSTRY | 9 | Oct 3, 2025 | clinicaltrials |
| NCT01896479 | A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancer(EXAMINER) | active not recruiting | Phase 4 | 247 | ExelixisINDUSTRY | 14 | Sep 2, 2025 | clinicaltrials |
| NCT04489888 | A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10) | completed | Phase 4 | 101 | Merck Sharp & Dohme LLCINDUSTRY | 5 | Jun 19, 2025 | clinicaltrials |
| NCT06879691 | A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma | active not recruiting | Phase 4 | 171 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Mar 17, 2025 | clinicaltrials |
| NCT04977271 | Mood Disorders in Head and Neck Cancer Patients | withdrawn | Phase 4 | 0 | University of Alabama at BirminghamOTHER | 0 | Feb 4, 2025 | clinicaltrials |
| NCT06807034 | Impact of the Oral Microbiota on Relapse in HNSCC Patients(MICR-ORL) | active not recruiting | Phase 4 | 100 | Institut Sainte CatherineOTHER | 1 | Feb 4, 2025 | clinicaltrials |
| NCT06697782 | Aprepitant and Ondansetron Monotherapy or Combination for Postoperative Nausea and Vomiting in Thyroid Cancer | completed | Phase 4 | 600 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06734598 | Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy | recruiting | Phase 4 | 120 | National Taiwan University HospitalOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT06521697 | Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery | unknown | Phase 4 | 60 | National Taiwan University HospitalOTHER | 0 | Jul 26, 2024 | clinicaltrials |
| NCT05949424 | OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults(OPTI-DOSE) | unknown | Phase 4 | 30 | University Medical Center GroningenOTHER | 1 | Nov 29, 2023 | clinicaltrials |
| NCT05830500 | Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma | recruiting | Phase 4 | 360 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jul 25, 2023 | clinicaltrials |
| NCT03691441 | Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer | unknown | Phase 4 | 280 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05046028 | Individualization of Nutritive Sensory Support Of Radiation Therapy | completed | Phase 4 | 100 | National Medical Research Radiological Centre of the Ministry of Health of RussiaOTHER | 1 | Mar 24, 2023 | clinicaltrials |
| NCT04155008 | Nutrition and Pharmacological Algorithm for Oncology Patients Study | terminated | Phase 4 | 1 | Montefiore Medical CenterOTHER | 1 | Nov 16, 2022 | clinicaltrials |
| NCT05055726 | Benzydamine Oromucosal Solution in Oral Mucositis (BOOM)(BOOM) | completed | Phase 4 | 100 | Aziende Chimiche Riunite Angelini Francesco S.p.AINDUSTRY | 2 | Nov 16, 2022 | clinicaltrials |
| NCT03065218 | 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients | terminated | Phase 4 | 4 | Medstar Health Research InstituteOTHER | 1 | Jul 26, 2022 | clinicaltrials |
| NCT01553032 | Skin Changes in Head and Neck Cancer During Immuno-(Chemo-) And Radiotherapy With Erbitux® (HICARE)(HICARE) | completed | Phase 4 | 139 | University of Heidelberg Medical CenterOTHER | 1 | May 25, 2022 | clinicaltrials |
| NCT05247476 | Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients. | unknown | Phase 4 | 50 | Zhongshan Hospital Xiamen UniversityOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT03469310 | Minimizing Narcotic Analgesics After Endocrine Surgery | completed | Phase 4 | 126 | Minerva A Romero ArenasOTHER | 1 | May 11, 2021 | clinicaltrials |
| NCT03607227 | Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery | completed | Phase 4 | 24 | Region SkaneOTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04766827 | Albumin-bound Paclitaxel Combined With Cisplatin Versus Docetaxel Combined With Cisplatin Induced Chemotherapy in Advanced Head and Neck Squamous Tummor | unknown | Phase 4 | 116 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT02946918 | Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy | terminated | Phase 4 | 14 | University of Texas Southwestern Medical CenterOTHER | 1 | Dec 1, 2020 | clinicaltrials |
| NCT04507035 | Treating Locally Advanced Head and Neck Malignant Tumor With Anlotinib and Chemoradiotherapy | unknown | Phase 4 | 30 | Sun Yat-sen UniversityOTHER | 1 | Aug 28, 2020 | clinicaltrials |
| NCT03196843 | Radiotherapy Combine With Raltitrexed Versus Radiotherapy Alone in Older Patients With HNSCC. | unknown | Phase 4 | 202 | The First Affiliated Hospital of Dalian Medical UniversityOTHER | 1 | Aug 7, 2020 | clinicaltrials |
| NCT04292990 | Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients | unknown | Phase 4 | 300 | Jiarong Chen, MDOTHER | 0 | Jul 29, 2020 | clinicaltrials |
| NCT03714867 | Pre-Operative Pregabalin for Post-Operative Pain in Head and Neck Cancer Surgery | withdrawn | Phase 4 | 0 | Augusta UniversityOTHER | 1 | Jul 9, 2020 | clinicaltrials |
| NCT01344356 | Stereotactic Body Radiotherapy for Head and Neck Tumors | completed | Phase 4 | 19 | Mercy ResearchOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT03969108 | Diagnostic Accuracy Study of Indocyanine Green for Parathyroid Perfusion Assessment | completed | Phase 4 | 10 | University Health Network, TorontoOTHER | 1 | Mar 27, 2020 | clinicaltrials |
| NCT04261179 | Study Comparing Lymphoseek® vs. Albumin Nanocolloid in Head and Neck, Melanoma and Breast Cancer(SENTINELSEEK) | unknown | Phase 4 | 30 | Anna CrucetaOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT03998696 | An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer.(HNC) | completed | Phase 4 | 60 | Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshOTHER | 1 | Jun 28, 2019 | clinicaltrials |
| NCT02948699 | A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients | unknown | Phase 4 | 114 | Zhejiang Cancer HospitalOTHER | 1 | Dec 4, 2018 | clinicaltrials |
| NCT03684707 | Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions | unknown | Phase 4 | 30 | Ain Shams UniversityOTHER | 1 | Sep 26, 2018 | clinicaltrials |
| NCT02926573 | Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients(GABA) | completed | Phase 4 | 123 | Washington University School of MedicineOTHER | 1 | Aug 8, 2018 | clinicaltrials |
| NCT00666978 | Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking | completed | Phase 4 | 540 | Lisa Sanderson Cox, PhDOTHER | 1 | Nov 13, 2017 | clinicaltrials |
| NCT00198263 | Study Using the Medpulser Electroporation System With Bleomycin to Treat Head and Neck Cancer | completed | Phase 4 | 95 | Inovio PharmaceuticalsINDUSTRY | 1 | Oct 3, 2017 | clinicaltrials |
| NCT03017053 | The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor | unknown | Phase 4 | 270 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Jan 11, 2017 | clinicaltrials |
| NCT01915485 | Radiolabeled Molecules for Medullary Thyroid Cancer | unknown | Phase 4 | 20 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Sep 7, 2016 | clinicaltrials |
| NCT02880072 | Absorption of Orally Ingested Phosphate in Refeeding Syndrome | completed | Phase 4 | 12 | Jens Rikardt AndersenOTHER | 1 | Aug 26, 2016 | clinicaltrials |
Data updated 11 hours agoSource updated Sep 29, 2026source: clinicaltrials