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CancerIndex

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Malignant Brain Glioma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Nervous System Neoplasm
Central Nervous System Neoplasm
Malignant Central Nervous System Neoplasm
Malignant Glioma
Malignant Brain Glioma

Subtype

Malignant Brain Glioma

CI-CAN-00005868Explore in graph →

75 active trials5 evidence items

NCIt: C162993

Overview
Statistics
Survival
Genomics
Variants & evidence5
Drugs1
Trials187
Research
Rankings
Sources & provenance

Data completeness3 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (data present)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A grade 3 or 4 glioma that arises from the brain. This category includes anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligoastrocytoma, anaplastic oligodendroglioma, anaplastic pleomorphic xanthoastrocytoma (all grade 3 gliomas), and glioblastoma (grade 4 glioma).

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Malignant Brain NeoplasmSubtype
Malignant GliomaSubtype
Primary Brain NeoplasmSubtype

Children (11)

ncit

Anaplastic Brain Stem Glioma1 sub
Anaplastic Diencephalic Astrocytoma
Brain Glioblastoma4 sub
Childhood Brain Anaplastic Astrocytoma2 sub
Diffuse Hemispheric Glioma, H3 G34-Mutant2 sub
Diffuse Intrinsic Pontine Glioma2 sub
Diffuse Pediatric-Type High Grade Glioma, H3-Wildtype and IDH-Wildtype

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00005868
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 6
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 187 / 75

5 sub

Frontal Lobe Anaplastic Oligodendroglioma

Hemispheric Anaplastic Astrocytoma4 sub

Infant-Type Hemispheric Glioma4 sub

Secondary Supratentorial Anaplastic Astrocytoma

47 descendants in total; counters on this page aggregate over all of them.

Publications (all / 5y)

37 / 8

Evidence items

5

Genes / variants

4 / 5

Drugs (any / approved)

1 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 3 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (3)

Brain High Grade Gliomasynonym · NCIt
Brain Malignant Gliomasynonym · NCIt
High Grade Brain Gliomasynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
Active trials75countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #224 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials43countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #211 of 1,284 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items5countaccepted CIViC items · entity + descendantscivicComputedrank #250 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months1countPubMed records · stored query · 12-month windowpubmedComputedrank #1866 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 3 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants