Clinical trial · Interventional
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective study that will conduct a series of focus groups with non-Hispanic Black and Hispanic childhood cancer survivors to obtain their input on culturally adapting a mobile CBT program for chronic pain and tDCS procedures. Once this adaptation process is completed, the investigators will conduct a feasibility trial with non-Hispanic Black, Hispanic and non-Hispanic White survivors of childhood cancer with chronic pain. The feasibility study will assign eligible participants to either culturally adapted mobile CBT + active tDCS to the dorsolateral prefrontal cortex or culturally adapted mobile CBT + sham tDCS. We anticipate approximately 60 participants for the focus groups and approximately 30 participants for the feasibility study for a total of about 90 participants.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Sarcoma | Bone Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Childhood Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cognitive Behavior Therapy | Behavioral | — | UNRESOLVED |
| Interview | Other | — | UNRESOLVED |
| Placebo Administration | Drug | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
| Transcranial Direct Current Stimulation | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Arm I (mobile CBT + active tDCS)
- description
- Participants receive mobile CBT and undergo active tDCS to the dorsolateral prefrontal cortex (DLPFC) over 20 minutes twice a week for 6 weeks.
- interventionNames
- Behavioral: Cognitive Behavior Therapy
- Device: Transcranial Direct Current Stimulation
- Other: Questionnaire Administration
- type
- SHAM_COMPARATOR
- label
- Arm II (mobile CBT + sham tDCS)
- description
- Participants receive mobile CBT and undergo sham tDCS to the DLPFC over 20 minutes twice a week for 6 weeks.
- interventionNames
- Behavioral: Cognitive Behavior Therapy
- Drug: Placebo Administration
- Other: Questionnaire Administration
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 10 Years
Show eligibility criteria text
Inclusions Criteria for cultural adaption * Adult * Hispanic or non-Hispanic Black childhood cancer survivor or parent of Hispanic or non-Hispanic Black childhood cancer survivor * 18 years or older * Adolescents * 10-17 years-old survivors of childhood cancer * At least one year post treatment * Hispanic or non-Hispanic Black * Phase 4 only: History of chronic pain (i.e. pain that was present for more than 3 months) Exclusion Criteria for cultural adaptation * Adults/Adolescents * Inability or unwillingness of research participants or legal guardian/representative to give written informed consent Inclusion Criteria for feasibility study * Hispanic, non-Hispanic Black and non-Hispanic White 10-17-year-old survivors of pediatric cancer * At least one year post treatment * Pain present over the past 3 months and pain at least once per week * Pain interfering with at least one area of daily functioning Exclusion Criteria for feasibility study * Limb amputation * History of seizures or other neurological disorders * Implanted medical device or metal in the head * Serious comorbid psychiatric condition * Current substance abuse * History of development delay or significant cognitive impairment * History of brain tumor diagnosis
References
Publications (0)
Data not yet available