Gene
DLG5
discs large MAGUK scaffold protein 5
Explore in graph →CI-GENE-00043449HGNC:2904 ENSG00000151208 NCBI 9231 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (8)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22895193
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Adenocarcinoma (Genentech, Nature 2012) coadread_genentech | Colorectal Adenocarcinoma | Ssm | 8 | 72 | 11.1% | 182 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 4 | 38 | 10.5% | 65 | cbioportal |
| Prostate Adenocarcinoma (Fred Hutchinson CRC, Nat Med 2016) prad_fhcrc | Prostate Adenocarcinoma | Ssm | 9 | 141 | 6.4% | 98 | cbioportal |
| Breast Invasive Carcinoma (British Columbia, Nature 2012) brca_bccrc | Invasive Breast Carcinoma | Ssm | 3 | 65 | 4.6% | 21 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.