Hematologic Malignancy
Diffuse Large B-Cell Lymphoma Unclassifiable
CI-CAN-00005111Explore in graph →
Hematologic11 active trials1 evidence items
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Hematologic Malignancy
CI-CAN-00005111Explore in graph →
Genomics
6 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,001 cases with simple somatic mutation data · 1,001 cases total · 2026-01-07 · mapped to Diffuse Large B-Cell Lymphoma Unclassifiable EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KMT2D | Ssm | 247 | 1,001 | 24.7% | cbioportal |
| 2 | MYD88 | Ssm | 172 | 1,001 | 17.2% | cbioportal |
| 3 | PIM1 | Ssm | 147 | 1,001 | 14.7% | cbioportal |
| 4 | CREBBP | Ssm | 115 | 1,001 | 11.5% | cbioportal |
| 5 | H1-4 | Ssm | 105 | 1,001 | 10.5% | cbioportal |
| 6 | BCL2 | Ssm | 101 | 1,001 | 10.1% | cbioportal |
| 7 | SPEN | Ssm | 101 | 1,001 | 10.1% | cbioportal |
| 8 | ARID1A |
Data updated 21 days agoSource updated 2026-01-07
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 96 |
| 1,001 |
| 9.6% |
| cbioportal |
| 9 | TP53 | Ssm | 93 | 1,001 | 9.3% | cbioportal |
| 10 | SOCS1 | Ssm | 92 | 1,001 | 9.2% | cbioportal |
| 11 | CARD11 | Ssm | 89 | 1,001 | 8.9% | cbioportal |
| 13 | GNA13 | Ssm | 83 | 1,001 | 8.3% | cbioportal |
| 14 | SETD1B | Ssm | 83 | 1,001 | 8.3% | cbioportal |
| 12 | ARID1B | Ssm | 83 | 1,001 | 8.3% | cbioportal |
| 15 | TNFRSF14 | Ssm | 79 | 1,001 | 7.9% | cbioportal |
| 16 | DUSP2 | Ssm | 76 | 1,001 | 7.6% | cbioportal |
| 17 | MGA | Ssm | 75 | 1,001 | 7.5% | cbioportal |
| 18 | SMARCA4 | Ssm | 75 | 1,001 | 7.5% | cbioportal |
| 19 | NOTCH2 | Ssm | 73 | 1,001 | 7.3% | cbioportal |
| 20 | ATM | Ssm | 72 | 1,001 | 7.2% | cbioportal |
| 21 | ZNF608 | Ssm | 68 | 1,001 | 6.8% | cbioportal |
| 22 | KLHL6 | Ssm | 67 | 1,001 | 6.7% | cbioportal |
| 23 | SGK1 | Ssm | 67 | 1,001 | 6.7% | cbioportal |
| 26 | MTOR | Ssm | 64 | 1,001 | 6.4% | cbioportal |
| 24 | BIRC6 | Ssm | 64 | 1,001 | 6.4% | cbioportal |
| 25 | IRF8 | Ssm | 64 | 1,001 | 6.4% | cbioportal |
| 27 | PIK3CD | Ssm | 63 | 1,001 | 6.3% | cbioportal |
| 28 | SETD2 | Ssm | 62 | 1,001 | 6.2% | cbioportal |
| 29 | TET2 | Ssm | 62 | 1,001 | 6.2% | cbioportal |
| 30 | EZH2 | Ssm | 61 | 1,001 | 6.1% | cbioportal |