Hematologic Malignancy
Diffuse Large B-Cell Lymphoma Unclassifiable
CI-CAN-00005111Explore in graph →
Hematologic11 active trials1 evidence items
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Hematologic Malignancy
CI-CAN-00005111Explore in graph →
Variants & evidence
1 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| EZH2 expression1 | ||||||||
| Tazemetostat | Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type | Predictive | C | Supports Sensitivity Response | 1 | accepted | EID11108In this phase I study (clinical trial NCT03009344), one patient with germinal center B‐cell‐like (GCB) DLBCL and two with non-GCB DLBCL types were recruited to test the efficacy of EZH2 inhibitor-Taze… (full text at CIViC) PMID 33492746 · Munakata et al., 2021 · Open in CIViC | civic |
Data updated 21 hours agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.