Cancer Family
Carcinoma
CI-CAN-00000114Explore in graph →
7,363 active trials118 approved drugs1,149 evidence items
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Cancer Family
CI-CAN-00000114Explore in graph →
Genomics
305 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
57 cases with simple somatic mutation data · 57 cases total · 2026-01-13 · mapped to Uterine Malignant Mixed Mesodermal (Mullerian) Tumor EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 52 |
| 57 |
| 91.2% |
| cbioportal |
| 2 | FBXW7 | Ssm | 22 | 57 | 38.6% | cbioportal |
| 3 | FRG1BP | Ssm | 21 | 57 | 36.8% | cbioportal |
| 4 | PIK3CA | Ssm | 20 | 57 | 35.1% | cbioportal |
| 5 | PPP2R1A | Ssm | 16 | 57 | 28.1% | cbioportal |
| 6 | MUC4 | Ssm | 13 | 57 | 22.8% | cbioportal |
| 7 | PTEN | Ssm | 11 | 57 | 19.3% | cbioportal |
| 8 | CHD4 | Ssm | 10 | 57 | 17.5% | cbioportal |
| 9 | TTN | Ssm | 10 | 57 | 17.5% | cbioportal |
| 10 | ARID1A | Ssm | 8 | 57 | 14% | cbioportal |
| 11 | KRAS | Ssm | 7 | 57 | 12.3% | cbioportal |
| 12 | LRP1B | Ssm | 7 | 57 | 12.3% | cbioportal |
| 13 | MUC17 | Ssm | 7 | 57 | 12.3% | cbioportal |
| 21 | SYNE1 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 18 | MUC16 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 20 | RB1 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 15 | FLNA | Ssm | 6 | 57 | 10.5% | cbioportal |
| 24 | ZNF814 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 22 | VPS13B | Ssm | 6 | 57 | 10.5% | cbioportal |
| 17 | MGAM | Ssm | 6 | 57 | 10.5% | cbioportal |
| 23 | ZBTB7B | Ssm | 6 | 57 | 10.5% | cbioportal |
| 19 | PIK3R1 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 14 | ARHGAP35 | Ssm | 6 | 57 | 10.5% | cbioportal |
| 16 | KMT2D | Ssm | 6 | 57 | 10.5% | cbioportal |
| 33 | PLEC | Ssm | 5 | 57 | 8.8% | cbioportal |
| 27 | FCGBP | Ssm | 5 | 57 | 8.8% | cbioportal |
| 28 | FER1L6 | Ssm | 5 | 57 | 8.8% | cbioportal |
| 29 | FLG | Ssm | 5 | 57 | 8.8% | cbioportal |
| 30 | LRP2 | Ssm | 5 | 57 | 8.8% | cbioportal |
| 26 | DOP1A | Ssm | 5 | 57 | 8.8% | cbioportal |
Data updated 22 days agoSource updated 2026-01-13