Cancer Family
Carcinoma
CI-CAN-00000114Explore in graph →
7,363 active trials118 approved drugs1,149 evidence items
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Cancer Family
CI-CAN-00000114Explore in graph →
Genomics
305 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
160 cases with simple somatic mutation data · 160 cases total · 2026-01-05 · mapped to Ampulla of Vater Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 99 |
| 160 |
| 61.9% |
| cbioportal |
| 2 | KRAS | Ssm | 86 | 160 | 53.8% | cbioportal |
| 3 | APC | Ssm | 36 | 160 | 22.5% | cbioportal |
| 4 | TTN | Ssm | 33 | 160 | 20.6% | cbioportal |
| 5 | SMAD4 | Ssm | 29 | 160 | 18.1% | cbioportal |
| 7 | SYNE1 | Ssm | 21 | 160 | 13.1% | cbioportal |
| 6 | PIK3CA | Ssm | 21 | 160 | 13.1% | cbioportal |
| 8 | ARID1A | Ssm | 17 | 160 | 10.6% | cbioportal |
| 9 | ARID2 | Ssm | 17 | 160 | 10.6% | cbioportal |
| 10 | ATM | Ssm | 17 | 160 | 10.6% | cbioportal |
| 13 | LRP1B | Ssm | 16 | 160 | 10% | cbioportal |
| 14 | NF1 | Ssm | 16 | 160 | 10% | cbioportal |
| 11 | CDKN2A | Ssm | 16 | 160 | 10% | cbioportal |
| 12 | KMT2C | Ssm | 16 | 160 | 10% | cbioportal |
| 15 | TGFBR2 | Ssm | 16 | 160 | 10% | cbioportal |
| 17 | MUC16 | Ssm | 15 | 160 | 9.4% | cbioportal |
| 16 | ERBB3 | Ssm | 15 | 160 | 9.4% | cbioportal |
| 18 | ZFHX4 | Ssm | 15 | 160 | 9.4% | cbioportal |
| 21 | ELF3 | Ssm | 14 | 160 | 8.8% | cbioportal |
| 19 | CTNNB1 | Ssm | 14 | 160 | 8.8% | cbioportal |
| 23 | MUC2 | Ssm | 14 | 160 | 8.8% | cbioportal |
| 22 | FAT3 | Ssm | 14 | 160 | 8.8% | cbioportal |
| 20 | DMD | Ssm | 14 | 160 | 8.8% | cbioportal |
| 24 | DNAH5 | Ssm | 13 | 160 | 8.1% | cbioportal |
| 25 | RNF43 | Ssm | 13 | 160 | 8.1% | cbioportal |
| 29 | KMT2D | Ssm | 12 | 160 | 7.5% | cbioportal |
| 31 | OBSCN | Ssm | 12 | 160 | 7.5% | cbioportal |
| 30 | MUC4 | Ssm | 12 | 160 | 7.5% | cbioportal |
| 32 | SMARCA4 | Ssm | 12 | 160 | 7.5% | cbioportal |
| 33 | TRPA1 | Ssm | 12 | 160 | 7.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05