PTEN

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
PTEN associated with …ASSOCIATED_WITH15 of 28show all (up to 200)
→ associated with	Malignant Breast Neoplasmcancer_family	supports	A	Malignant Breast Neoplasm	1	Curated	civic	graph →
→ associated with	Malignant Breast Neoplasmcancer_family 3 source records aggregated

PTEN has variant …HAS_VARIANTderived200 of 3,593show all (up to 200)
→ has variant	Lossdeletion_cna 33 accepted CIViC evidence items	—	—	Malignant Neoplasm,Solid Neoplasm,Malignant Breast Neoplasm+2	33	Curated	civic	graph →
→ has variant	Mutationother 9 accepted CIViC evidence items	—	—	Malignant Neoplasm,Solid Neoplasm,Malignant Breast Neoplasm+2	9	Curated	civic	graph →
→ has variant	Underexpressionexpression 6 accepted CIViC evidence items	—	—	Melanoma,HER2-Positive Breast Carcinoma	6	Curated	civic	graph →
→ has variant	Expressionexpression 5 accepted CIViC evidence items	—	—	Malignant Breast Neoplasm,Glioblastoma,HER2-Positive Breast Carcinoma	5	Curated	civic	graph →
→ has variant	Deletiondeletion_cna 3 accepted CIViC evidence items	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm	3	Curated	civic	graph →
→ has variant	R173CSNV 3 accepted CIViC evidence items	—	—	Malignant Neoplasm	3	Curated	civic	graph →
→ has variant	R233*SNV 2 accepted CIViC evidence items	—	—	Malignant Breast Neoplasm,Glioblastoma	2	Curated	civic	graph →
→ has variant	C136RSNV 1 accepted CIViC evidence items	—	—	not mapped	1	Curated	civic	graph →
→ has variant	R130*SNV 1 accepted CIViC evidence items	—	—	Malignant Thyroid Gland Neoplasm	1	Curated	civic	graph →
→ has variant	V317FSindel 1 accepted CIViC evidence items	—	—	Cutaneous Melanoma	1	Curated	civic	graph →
→ has variant	A121ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	A126DSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	A126SSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Alterations no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	c.1003C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	C124SSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	c.209+5G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D107GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D107VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D162GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D92ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D92ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D92GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D92HSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D92VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	E91ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	F241SSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	F90LSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G127ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G129ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G129RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G129VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G165ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G165RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G165VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G36RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H123DSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H93DSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H93QSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H93RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H93YSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	I122SSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	I168FSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Inactivating alteration no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K125ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K128NSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N94ISNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.10:g.(?_89622918)_(89624325_?)dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_86875868)_(87894129_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87862876A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87863171)_(87864558_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87863235C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87863494G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87863570_87863591dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87863624A>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87863625)_(87971930_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87864104deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87894015)_(87894119_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87894015)_(87965482_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87894025)_(87894109_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87931026)_(87958039_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87931036)_(87931099_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87931040)_(87933257_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87952112)_(87952265_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87952119deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87957853_87957860deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87960841)_(87960878_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.(?_87960888)_(87961124_?)deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87960894deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000010.11:g.87965287deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1002C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1002C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1005C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1005C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1005C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1009C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1010C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1010C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1020C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1021C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1026C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1026C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1028C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1029T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1031C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1032-222_-366del889deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1033_-1029delGCCCTother no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1037C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1039_-1030del10other no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1042C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1046C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1047C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1048C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1049C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1052C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1056C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1060C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1060C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1062C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1062C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1067_-1038del30deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1070C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1070C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1076G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1079C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1079C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1080C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1083G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1085T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1095G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1096G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1097G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1098G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1103G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1108C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1124delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1124G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1125G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1125G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1125G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1133G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1135_-1134insTinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1137G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1141_-1140delCCdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1141C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1142C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1145A>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1145A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1151C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1151C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1152C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1152C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1154G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1154G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1160G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1161_-1160delGGinsAAindel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1161G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1165G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1168G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1168G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1172G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1172G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1172G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1180_-1164del17deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1187_-1185delGCAother no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1192C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1197A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1214T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1216C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1231G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1235C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1237G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1237G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1242G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1243delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1256G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1258C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1261C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1275A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1279C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1279dupCinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1284C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1284dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1285C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1286C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1287C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-1287C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-860delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-861G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-862_-847del16deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-862G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-862G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-862G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-868_-846dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-887T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-895_-894delTTdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-901delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-902G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-902G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-903_-882del22deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-903_-902insACTCTTTATGCGCTGCGGCAGinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-903G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-905delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-905dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-906G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-906G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-907T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-917G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-917G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-917G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-918G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-921G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-925G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-933G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-933G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-934G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-934G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-935G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-942G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000314.4(PTEN):c.-945G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

PTEN has variant …HAS_VARIANTderived200 of 3,593show all (up to 200)

→ has variant

Lossdeletion_cna

33 accepted CIViC evidence items

—

Malignant Neoplasm,Solid Neoplasm,Malignant Breast Neoplasm+2

Curated

civic

graph →

→ has variant

Mutationother

9 accepted CIViC evidence items

—

Malignant Neoplasm,Solid Neoplasm,Malignant Breast Neoplasm+2

Curated

civic

graph →

→ has variant

Underexpressionexpression

6 accepted CIViC evidence items

—

Melanoma,HER2-Positive Breast Carcinoma

Curated

civic

graph →

→ has variant

Expressionexpression

5 accepted CIViC evidence items

—

Malignant Breast Neoplasm,Glioblastoma,HER2-Positive Breast Carcinoma

Curated

civic

graph →

→ has variant

Deletiondeletion_cna

3 accepted CIViC evidence items

—

Prostate Adenocarcinoma,Malignant Prostate Neoplasm

Curated

civic

graph →

→ has variant

R173CSNV

3 accepted CIViC evidence items

—

Malignant Neoplasm

Curated

civic

graph →

→ has variant

R233*SNV

2 accepted CIViC evidence items

—

Malignant Breast Neoplasm,Glioblastoma

Curated

civic

graph →

→ has variant

C136RSNV

1 accepted CIViC evidence items

—

not mapped

Curated

civic

graph →

→ has variant

R130*SNV

1 accepted CIViC evidence items

—

Malignant Thyroid Gland Neoplasm

Curated

civic

graph →

→ has variant

V317FSindel

1 accepted CIViC evidence items

—

Cutaneous Melanoma

Curated

civic

graph →

→ has variant

A121ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

A126DSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

A126SSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

Alterations

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

c.1003C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

C124SSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

c.209+5G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D107GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D107VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D162GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D92ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D92ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D92GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D92HSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

D92VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

E91ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

F241SSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

F90LSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G127ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G129ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G129RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G129VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G165ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G165RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G165VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

G36RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

H123DSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

H93DSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

H93QSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

H93RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

H93YSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

I122SSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

I168FSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

Inactivating alteration

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

K125ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

K128NSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

N94ISNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.10:g.(?_89622918)_(89624325_?)dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_86875868)_(87894129_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87862876A>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87863171)_(87864558_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87863235C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87863494G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87863570_87863591dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87863624A>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87863625)_(87971930_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87864104deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87894015)_(87894119_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87894015)_(87965482_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87894025)_(87894109_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87931026)_(87958039_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87931036)_(87931099_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87931040)_(87933257_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87952112)_(87952265_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87952119deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87957853_87957860deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87960841)_(87960878_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.(?_87960888)_(87961124_?)deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87960894deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NC_000010.11:g.87965287deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1002C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1002C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1005C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1005C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1005C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1009C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1010C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1010C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1020C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1021C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1026C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1026C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1028C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1029T>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1031C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1032-222_-366del889deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1033_-1029delGCCCTother

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1037C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1039_-1030del10other

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1042C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1046C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1047C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1048C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1049C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1052C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1056C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1060C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1060C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1062C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1062C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1067_-1038del30deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1070C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1070C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1076G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1079C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1079C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1080C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1083G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1085T>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1095G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1096G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1097G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1098G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1103G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1108C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1124delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1124G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1125G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1125G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1125G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1133G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1135_-1134insTinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1137G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1141_-1140delCCdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1141C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1142C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1145A>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1145A>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1151C>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1151C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1152C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1152C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1154G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1154G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1160G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1161_-1160delGGinsAAindel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1161G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1165G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1168G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1168G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1172G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1172G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1172G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1180_-1164del17deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1187_-1185delGCAother

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1192C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1197A>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1214T>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1216C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1231G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1235C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1237G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1237G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1242G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1243delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1256G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1258C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1261C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1275A>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1279C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1279dupCinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1284C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1284dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1285C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1286C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1287C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-1287C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-860delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-861G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-862_-847del16deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-862G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-862G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-862G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-868_-846dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-887T>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-895_-894delTTdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-901delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-902G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-902G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-903_-882del22deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-903_-902insACTCTTTATGCGCTGCGGCAGinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-903G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-905delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-905dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-906G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-906G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-907T>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-917G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-917G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-917G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-918G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-921G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-925G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-933G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-933G>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-934G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-934G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-935G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-942G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_000314.4(PTEN):c.-945G>CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

PTEN altered in cohorts of …ALTERED_INderived13 of 13
→ altered in cohorts of	Endometrial Endometrioid Adenocarcinoma 194 / 247 cases (79 %) · ssm · uec_cptac_gdc	—	—	Endometrial Endometrioid Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Glioblastomasubtype 461 / 601 cases (77 %) · ssm · TCGA-GBM	—	—	Glioblastoma	1	Observed	gdc	graph →
→ altered in cohorts of	Endometrial Carcinoma 941 / 1,882 cases (50 %) · ssm · ucec_ancestry_cds_msk_2023 · largest of 11 cohorts	—	—	Endometrial Carcinoma	11	Observed	cbioportal	graph →
→ altered in cohorts of	Diffuse Glioma 246 / 1,004 cases (25 %) · ssm · glioma_mskcc_2019 · largest of 11 cohorts	—	—	Diffuse Glioma	11	Observed	cbioportal	graph →
→ altered in cohorts of	Cutaneous Melanoma 82 / 696 cases (12 %) · ssm · mel_mskimpact_2020	—	—	Cutaneous Melanoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Squamous Cell Carcinoma 51 / 484 cases (11 %) · ssm · lusc_tcga_gdc · largest of 2 cohorts	—	—	Lung Squamous Cell Carcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Invasive Breast Carcinoma 303 / 3,879 cases (7.8 %) · ssm · breast_msk_2025 · largest of 6 cohorts	—	—	Invasive Breast Carcinoma	6	Observed	cbioportal	graph →
→ altered in cohorts of	Prostate Adenocarcinomasubtype 155 / 2,069 cases (7.5 %) · ssm · prad_msk_stopsack_2021 · largest of 6 cohorts	—	—	Prostate Adenocarcinoma	6	Observed	cbioportal	graph →
→ altered in cohorts of	Acute Lymphoblastic Leukemia 57 / 768 cases (7.4 %) · ssm · TARGET-ALL-P2	—	—	Acute Lymphoblastic Leukemia	1	Observed	gdc	graph →
→ altered in cohorts of	Cervical Squamous Cell Carcinoma 21 / 291 cases (7.2 %) · ssm · cesc_tcga_pan_can_atlas_2018 · largest of 2 cohorts	—	—	Cervical Squamous Cell Carcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Rectal Adenocarcinoma 446 / 7,237 cases (6.2 %) · ssm · crc_msk_2026	—	—	Rectal Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Non-Small Cell Carcinoma 77 / 1,257 cases (6.1 %) · ssm · nsclc_ctdx_msk_2022	—	—	Lung Non-Small Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Colorectal Adenocarcinoma 68 / 1,134 cases (6.0 %) · ssm · crc_msk_2017 · largest of 2 cohorts	—	—	Colorectal Adenocarcinoma	2	Observed	cbioportal	graph →

PTEN altered in cohorts of …ALTERED_INderived13 of 13

→ altered in cohorts of

Endometrial Endometrioid Adenocarcinoma

194 / 247 cases (79 %) · ssm · uec_cptac_gdc

—

Endometrial Endometrioid Adenocarcinoma

Observed

cbioportal

graph →

→ altered in cohorts of

Glioblastomasubtype

461 / 601 cases (77 %) · ssm · TCGA-GBM