| Talazoparib studied in …STUDIED_INderived99 of 99show fewer |
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| → studied in | NCT05327010Phase 2 · active not recruiting Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02693535Phase 2 · recruiting TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Multiple Myeloma,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04693468Phase 1 · recruiting Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04982848withdrawn Korea Post Marketing Surveillance (PMS) Study of Talzenna® · 99 trials list this drug (33 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03964532Phase 1/Phase 2 · active not recruiting TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05142241Phase 2 · active not recruiting Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04019327Phase 1/Phase 2 · terminated A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancer · 99 trials list this drug (33 active) | — | — | Prostate Adenocarcinoma,Prostate Neoplasm,Malignant Prostate Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06844383Phase 2 · recruiting A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide · 99 trials list this drug (33 active) | — | — | Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04550494Phase 2 · active not recruiting Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm,Breast Carcinoma,Malignant Pancreatic Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02912572Phase 2 · active not recruiting Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer · 99 trials list this drug (33 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04039230Phase 1/Phase 2 · active not recruiting Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer. · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05059522Phase 3 · active not recruiting Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Lung Non-Small Cell Carcinoma,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05071937Phase 2 · recruiting ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer · 99 trials list this drug (33 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02286687Phase 2 · active not recruiting Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes · 99 trials list this drug (33 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05873192Phase 2 · recruiting Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer · 99 trials list this drug (33 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04334941Phase 2 · active not recruiting Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker · 99 trials list this drug (33 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04901702Phase 1/Phase 2 · recruiting Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Hepatoblastoma,Malignant Germ Cell Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04846478Phase 1 · active not recruiting Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC · 99 trials list this drug (33 active) | — | — | Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03990896Phase 2 · recruiting Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04511039Phase 1 · recruiting Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm,Colorectal Adenocarcinoma,Colorectal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05101551Phase 1 · recruiting Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy · 99 trials list this drug (33 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04486352Phase 1/Phase 2 · recruiting A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer · 99 trials list this drug (33 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03968406Phase 1 · recruiting Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers · 99 trials list this drug (33 active) | — | — | Primary Peritoneal Carcinoma,Malignant Fallopian Tube Neoplasm,Malignant Female Reproductive System Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03974217Phase 1 · active not recruiting Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts · 99 trials list this drug (33 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04734730Phase 2 · recruiting Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer · 99 trials list this drug (33 active) | — | — | Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Sensitive Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04991480Phase 1 · completed A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors · 99 trials list this drug (33 active) | — | — | Malignant Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03672773Phase 2 · active not recruiting Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer · 99 trials list this drug (33 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04497116Phase 1/Phase 2 · completed Study of RP-3500, Camonsertib, in Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03901469Phase 2 · terminated A Study of ZEN003694 and Talazoparib in Patients With Triple Negative Breast Cancer · 99 trials list this drug (33 active) | — | — | Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04756765Phase 2 · withdrawn Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06762808Phase 2 · withdrawn Phase II Study of Atezolizumab and Tiragolumab With ctDNA for HPV-positive SCC · 99 trials list this drug (33 active) | — | — | Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05035745Phase 1/Phase 2 · recruiting Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START) · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05650476available Pre-approval Single-patient Expanded Access for Talazoparib (PF-06944076) · 99 trials list this drug (33 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04740190Phase 2 · completed Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd · 99 trials list this drug (33 active) | — | — | Glioblastoma,Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04849364Phase 2 · terminated Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04337970Phase 1/Phase 2 · completed Talazoparib and Axitinib for People With Previously Treated Advanced Kidney Cancer · 99 trials list this drug (33 active) | — | — | Malignant Kidney Neoplasm,Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04332744Phase 2 · completed Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First) · 99 trials list this drug (33 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04892693Phase 2 · recruiting Talazoparib in Advanced Breast Cancer Patients With Homologous Recombinant Deficiency · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06193525Phase 2 · recruiting FUnctional Selection of Advanced Breast Cancer Patients for Talazoparib Treatment Using the REpair Capacity (RECAP) Test · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05053854Phase 1 · recruiting PARP Inhibitor With 177Lu-DOTA-Octreotate PRRT in Patients With Neuroendocrine Tumours · 99 trials list this drug (33 active) | — | — | Neuroendocrine Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04703920Phase 1 · completed Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Ovarian Carcinoma,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04187833Phase 2 · completed Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05097599Phase 2 · terminated StrataPATH™ (Precision Indications for Approved Therapies) · 99 trials list this drug (33 active) | — | — | Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04068831Phase 2 · completed Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma · 99 trials list this drug (33 active) | — | — | Renal Cell Carcinoma,Fumarate Hydratase-Deficient Renal Cell Carcinoma,Succinate Dehydrogenase-Deficient Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04207190Phase 1 · completed Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia · 99 trials list this drug (33 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04672460Phase 1 · completed A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Malignant Pancreatic Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04173507Phase 2 · completed Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial) · 99 trials list this drug (33 active) | — | — | Malignant Lung Neoplasm,Lung Non-Squamous Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03343054Phase 1 · completed A Phase 1 Study Of Talazoparib, PARP Inhibitor, In Japanese Patients With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Neoplasm,Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03911973Phase 1/Phase 2 · active not recruiting Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06218628Phase 1 · recruiting Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition · 99 trials list this drug (33 active) | — | — | Chronic Myelomonocytic Leukemia,Essential Thrombocythemia,Polycythemia Vera+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03148795Phase 2 · completed A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate Cancer · 99 trials list this drug (33 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05319249Phase 1/Phase 2 · not yet recruiting Natural Killer Cell Immunotherapy in Combination With PARP-inhibition in Acute Myeloid Leukemia · 99 trials list this drug (33 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04134884Phase 1 · completed Study of ASTX727 Plus Talazoparib in Patients With Triple Negative or Hormone Resistant/HER2-negative Metastatic Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05141708completed Treatment Patterns and Clinical Outcomes Among Talazoparib-Treated Adults With HER2-Negative mBC With gBRCA1/2m · 99 trials list this drug (33 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02925234Phase 2 · recruiting The Drug Rediscovery Protocol (DRUP Trial) · 99 trials list this drug (33 active) | — | — | Neoplasm,Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04987931completed Real-World Outcomes of US Talazoparib-Treated Patients With Locally Advanced or Metastatic Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05425862Phase 1 · suspended Pidnarulex and Talazoparib in Patients With Metastatic Castration Resistant Prostate Cancer · 99 trials list this drug (33 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04690855Phase 2 · terminated A Study to Evaluate TAlazoparib, Radiotherapy and Atezolizumab in gBRCA 1/2 Negative Patients With PD-L1+ Metastatic Triple Negative Breast Cancer · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04598321Phase 1 · terminated BrUOG 390: Neoadjuvant Treatment With Talazoparib · 99 trials list this drug (33 active) | — | — | Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04635631Phase 1 · completed STUDY OF TALAZOPARIB MONOTHERAPY IN CHINESE PARTICIPANTS WITH ADVANCED SOLID TUMORS · 99 trials list this drug (33 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04591431Phase 2 · unknown The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Malignant Digestive System Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03565991Phase 2 · terminated Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02317874Phase 1 · completed Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer · 99 trials list this drug (33 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02154490completed Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer · 99 trials list this drug (33 active) | — | — | Lung Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04801966NA · terminated Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study · 99 trials list this drug (33 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02878785Phase 1/Phase 2 · completed Decitabine and Talazoparib in Untreated AML and R/R AML · 99 trials list this drug (33 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03426254Phase 1 · withdrawn Comparison of Safety and Clinical Benefit of Injections Subcutaneously Talazoparib Versus Oral Talazoparib in Patients With Solid Tumors · 99 trials list this drug (33 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02401347Phase 2 · completed Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors · 99 trials list this drug (33 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05725200Phase 2 · recruiting Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer · 99 trials list this drug (33 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02921919Phase 2 · completed Open-Label Extension and Safety Study of Talazoparib · 99 trials list this drug (33 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02282345Phase 2 · completed Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer · 99 trials list this drug (33 active) | — | — | Breast Adenocarcinoma,Invasive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05288127Phase 2 · unknown Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature · 99 trials list this drug (33 active) | — | — | Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02316834early Phase 1 · completed Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · 99 trials list this drug (33 active) | — | — | Malignant Fallopian Tube Neoplasm,Fallopian Tube Serous Adenocarcinoma,Primary Peritoneal Serous Adenocarcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03875313Phase 1/Phase 2 · terminated Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Clear Cell Renal Cell Carcinoma,Colorectal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03637491Phase 1/Phase 2 · terminated A Study of Avelumab, Binimetinib and Talazoparib in Patients With Locally Advanced or Metastatic RAS-mutant Solid Tumors · 99 trials list this drug (33 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01945775Phase 3 · completed A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study) · 99 trials list this drug (33 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03499353Phase 2 · terminated Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer · 99 trials list this drug (33 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04052204Phase 1/Phase 2 · terminated Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors · 99 trials list this drug (33 active) | — | — | Head and Neck Squamous Cell Carcinoma,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02127151Phase 2 · withdrawn A Parp Inhibitor (BMN 673) for Inoperable Advanced eNDometrial cAncer · 99 trials list this drug (33 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03077607Phase 1 · completed A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03377556Phase 2 · completed Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer · 99 trials list this drug (33 active) | — | — | Lung Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04824937Phase 2 · unknown Telaglenastat + Talazoparib In Prostate Cancer · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02116777Phase 1/Phase 2 · completed Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies · 99 trials list this drug (33 active) | — | — | Adult Solid Neoplasm,Central Nervous System Neoplasm,Childhood Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02997176Phase 1 · completed An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800) · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01989546Phase 1/Phase 2 · completed Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04755868Phase 2 · unknown Talazoparib Maintenance Therapy in Triple-negative Breast Cancer · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02392793Phase 1 · completed Talazoparib Plus Irinotecan With or Without Temozolomide in Children With Refractory or Recurrent Solid Malignancies · 99 trials list this drug (33 active) | — | — | Childhood Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02997163Phase 1 · completed An Open-Label Pharmacokinetics and Safety Study of Talazoparib · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04462809Phase 2 · unknown Efficacy of a Maintenance Treatment With TALAzoparib Following First Line Platinum-based Chemotherapy in Malignant MESOthelioma · 99 trials list this drug (33 active) | — | — | Malignant Mesothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02358200Phase 1 · terminated Study of BMN-673 With Carboplatin and Paclitaxel in Patients With Advanced BRCA-mutated Solid Tumor or Triple Negative Metastatic Breast Cancer · 99 trials list this drug (33 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03042910Phase 1 · completed A Study to Assess the Effects of Talazoparib on Cardiac Repolarization in Patients With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02034916Phase 2 · terminated A Phase 2, 2-Stage, 2-Cohort Study of Talazoparib (BMN 673), in Locally Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (ABRAZO Study) · 99 trials list this drug (33 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01286987Phase 1 · completed Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors · 99 trials list this drug (33 active) | — | — | Breast Neoplasm,Ewing Sarcoma,Ovarian Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03070548Phase 1 · completed A Study of Talazoparib in Patients With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02836028Phase 2 · withdrawn A Study Evaluating Talazoparib in Relapsed Ovarian, Fallopian Tube, and Peritoneal Cancer · 99 trials list this drug (33 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01399840Phase 1 · completed Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignancies · 99 trials list this drug (33 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Chronic Lymphocytic Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02567396Phase 1 · withdrawn Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Malignant Mesothelioma,Malignant Gastric Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02627430Phase 1 · withdrawn Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced Solid Tumor or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple Negative Breast Cancer · 99 trials list this drug (33 active) | — | — | Adult Solid Neoplasm,Breast Carcinoma,Ovarian Serous Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02537561Phase 1 · withdrawn Talazoparib in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors · 99 trials list this drug (33 active) | — | — | Solid Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |