| Ruxolitinib studied in …STUDIED_INderived177 of 177show fewer |
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| → studied in | NCT07722611Phase 2/Phase 3 · recruiting A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025) · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06150157Phase 1 · recruiting A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms · 177 trials list this drug (74 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07840456Phase 2 · not yet recruiting Safety and Efficacy of Ruxolitinib in Patients With HNSCC and High NLR Treated With Pembrolizumab - The Phase 2 InflammaSTOP Trial · 177 trials list this drug (74 active) | — | — | Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02974647Phase 2 · recruiting Study of Ruxolitinib in Relapsed or Refractory T or NK Cell Lymphoma · 177 trials list this drug (74 active) | — | — | Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03874052Phase 1 · recruiting Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia · 177 trials list this drug (74 active) | — | — | Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia,Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04744116early Phase 1 · recruiting Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07025538Phase 1 · recruiting Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphatic System Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04282187Phase 2 · recruiting Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms · 177 trials list this drug (74 active) | — | — | Myelodysplastic Syndrome,Myelodysplastic/Myeloproliferative Neoplasm,Myeloproliferative Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06987058Phase 2 · enrolling by invitation RVU120 Rollover Study · 177 trials list this drug (74 active) | — | — | Solid Neoplasm,Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06397313Phase 2 · terminated RVU120 in Patients With Intermediate or High-risk, Primary or Secondary Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07032727Phase 2 · recruiting Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05010005Phase 1 · recruiting A Study of Ruxolitinib and Duvelisib in People With Lymphoma · 177 trials list this drug (74 active) | — | — | T-Cell Large Granular Lymphocyte Leukemia,T-Cell Non-Hodgkin Lymphoma,T-Cell Prolymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07796620Phase 1/Phase 2 · not yet recruiting Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI · 177 trials list this drug (74 active) | — | — | Acute Leukemia,Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02131584Phase 2 · active not recruiting Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic Leukemia · 177 trials list this drug (74 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07249346Phase 2 · recruiting Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation · 177 trials list this drug (74 active) | — | — | Leukemia,Myelodysplastic Syndrome,Chronic Myelomonocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03801434Phase 2 · active not recruiting Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders · 177 trials list this drug (74 active) | — | — | Chronic Eosinophilic Leukemia, Not Otherwise Specified | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06291987Phase 1 · recruiting Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02386800Phase 4 · active not recruiting CINC424A2X01B Rollover Protocol · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia,Polycythemia Vera,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07228624Phase 2 · recruiting Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes · 177 trials list this drug (74 active) | — | — | Myelodysplastic/Myeloproliferative Neoplasm,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02955940Phase 2 · active not recruiting An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib · 177 trials list this drug (74 active) | — | — | Malignant Breast Neoplasm,Malignant Lung Neoplasm,Malignant Pancreatic Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02577926Phase 2 · active not recruiting The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia · 177 trials list this drug (74 active) | — | — | Essential Thrombocythemia,Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07311746Phase 1/Phase 2 · recruiting Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia · 177 trials list this drug (74 active) | — | — | T-Cell Prolymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05936359Phase 1 · active not recruiting A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07131059NA · recruiting MRD-positive AML Clinical Study · 177 trials list this drug (74 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06991101Phase 2 · recruiting Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma · 177 trials list this drug (74 active) | — | — | Glioblastoma,Adult Glioblastoma,Brain Glioblastoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02876302Phase 2 · completed Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer · 177 trials list this drug (74 active) | — | — | Breast Inflammatory Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05098210Phase 1 · recruiting Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer · 177 trials list this drug (74 active) | — | — | Malignant Solid Neoplasm,Conjunctival Melanoma,Cutaneous Melanoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03120624Phase 1 · active not recruiting VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer · 177 trials list this drug (74 active) | — | — | Uterine Corpus Carcinosarcoma,Endometrial Adenocarcinoma,Endometrial Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07128381Phase 1/Phase 2 · recruiting Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML) · 177 trials list this drug (74 active) | — | — | Chronic Myelomonocytic Leukemia,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04328844Phase 1 · active not recruiting A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers · 177 trials list this drug (74 active) | — | — | Adult Solid Neoplasm,Uveal Melanoma,Adult Non-Hodgkin Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07359859Phase 2 · recruiting A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07464951Phase 1 · recruiting CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02494882Phase 1 · active not recruiting Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or Older · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04217356active not recruiting Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis · 177 trials list this drug (74 active) | — | — | Bone Marrow Neoplasm,Malignant Bone Marrow Neoplasm,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07548983Phase 1 · recruiting Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03722407Phase 2 · active not recruiting Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion · 177 trials list this drug (74 active) | — | — | Leukemia,Chronic Myelomonocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06508463Phase 1 · recruiting Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma · 177 trials list this drug (74 active) | — | — | Anaplastic Large Cell Lymphoma,Mycosis Fungoides,Peripheral T-Cell Lymphoma, Not Otherwise Specified | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03571321Phase 1 · recruiting Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Childhood Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03117751Phase 2/Phase 3 · active not recruiting Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03681561Phase 1/Phase 2 · recruiting Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma · 177 trials list this drug (74 active) | — | — | Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03017820Phase 1 · recruiting A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma · 177 trials list this drug (74 active) | — | — | Histiocytic and Dendritic Cell Neoplasm,Anaplastic Large Cell Lymphoma,B-Cell Non-Hodgkin Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07278856Phase 1 · recruiting Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas · 177 trials list this drug (74 active) | — | — | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma,Follicular Helper T-Cell Lymphoma,Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02158858Phase 1/Phase 2 · completed A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies · 177 trials list this drug (74 active) | — | — | Neoplasm,Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03514069Phase 1 · completed Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma · 177 trials list this drug (74 active) | — | — | Glioblastoma,Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02493530Phase 1 · completed TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea · 177 trials list this drug (74 active) | — | — | Polycythemia Vera,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05088356Phase 1 · active not recruiting Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Acute Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04817007Phase 1/Phase 2 · active not recruiting A Study to Assess the Safety and Tolerability of BMS-986158 Alone and in Combination With Either Ruxolitinib or Fedratinib in Participants With Blood Cancer (Myelofibrosis) · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06616155Phase 1/Phase 2 · recruiting Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer · 177 trials list this drug (74 active) | — | — | Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07566897Phase 1 · not yet recruiting A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid Tumors · 177 trials list this drug (74 active) | — | — | Colorectal Carcinoma,Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06399029Phase 2 · active not recruiting Topical Ruxolitinib Evaluation in Immune-related Lichenoid Skin-Toxicities · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04116502Phase 3 · recruiting MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878199Phase 1/Phase 2 · terminated Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm,Secondary Acute Myeloid Leukemia,Essential Thrombocythemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06034002Phase 1 · recruiting A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07356245Phase 2 · recruiting Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma · 177 trials list this drug (74 active) | — | — | Adult T-Cell Leukemia/Lymphoma,Primary Cutaneous T-Cell Non-Hodgkin Lymphoma,T-Cell Non-Hodgkin Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02928978Phase 2 · completed Ruxolitinib for Premalignant Breast Disease · 177 trials list this drug (74 active) | — | — | Breast Atypical Lobular Hyperplasia,Breast Lobular Carcinoma In Situ,Breast Atypical Ductal Hyperplasia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04562389Phase 3 · active not recruiting Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03610971Phase 2 · active not recruiting Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors · 177 trials list this drug (74 active) | — | — | Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04279847Phase 1 · active not recruiting Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms · 177 trials list this drug (74 active) | — | — | Myelodysplastic Syndrome,Myeloproliferative Neoplasm,Essential Thrombocythemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01787487Phase 2 · completed Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm · 177 trials list this drug (74 active) | — | — | Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified,Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03286530Phase 2 · active not recruiting Ruxolitinib + Allogeneic Stem Cell Transplantation in AML · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04472598Phase 3 · completed Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00044304Phase 2 · active not recruiting Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02723994Phase 2 · completed A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia · 177 trials list this drug (74 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05592015Phase 2 · recruiting Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia · 177 trials list this drug (74 active) | — | — | T-Cell Large Granular Lymphocyte Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07366801Phase 2/Phase 3 · recruiting Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06768476Phase 1 · active not recruiting CART123 + Ruxolitinib in Relapsed/Refractory AML · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07219576Phase 1/Phase 2 · recruiting Retifanlimab and Ruxolitinib In Solid Malignancies · 177 trials list this drug (74 active) | — | — | Lung Non-Small Cell Carcinoma,Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04468984Phase 3 · active not recruiting Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04644211Phase 2 · recruiting Ruxolitinib in Thrombocythemia and Polycythemia Vera · 177 trials list this drug (74 active) | — | — | Essential Thrombocythemia,Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03654768Phase 2 · active not recruiting Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia · 177 trials list this drug (74 active) | — | — | Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07283822Phase 2 · recruiting Amping up With PemJAK · 177 trials list this drug (74 active) | — | — | Non-Hodgkin Lymphoma,Primary Cutaneous T-Cell Non-Hodgkin Lymphoma,Gray-Zone Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03774082Phase 2 · completed Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07238712Phase 2 · recruiting Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched Donor · 177 trials list this drug (74 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Atypical Chronic Myeloid Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03274778NA · withdrawn Effect of Ruxolitinib on Tumor Infiltrating Myeloid Cells · 177 trials list this drug (74 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04745637available Managed Access Programs for INC424, Ruxolitinib · 177 trials list this drug (74 active) | — | — | Polycythemia Vera,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03674047Phase 2 · active not recruiting Ruxolitinib for Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplantation (HCT) · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06008275early Phase 1 · recruiting Neratinib in Combination With Ruxolitinib in Patients With mTNBC · 177 trials list this drug (74 active) | — | — | Malignant Breast Neoplasm,Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05269771no longer available MAP to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06128070Phase 2 · recruiting Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00726232Phase 2 · terminated Study to Determine the Safety and Efficacy of INCB018424 in Patients With Polycythemia Vera or Essential Thrombocythemia · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02711137Phase 1/Phase 2 · terminated Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies · 177 trials list this drug (74 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04551066Phase 3 · terminated To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313) · 177 trials list this drug (74 active) | — | — | Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04551053Phase 3 · terminated To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304) · 177 trials list this drug (74 active) | — | — | Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05579769Phase 2 · terminated Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies. · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05745714Phase 1/Phase 2 · recruiting HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04454658Phase 1 · active not recruiting Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04669210Phase 2 · completed PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00674479Phase 2 · completed INCB018424 in Patients With Advanced Hematologic Malignancies · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome,Myeloid Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01251965Phase 1/Phase 2 · terminated Phase l/II Study of Ruxolitinib for Acute Leukemia · 177 trials list this drug (74 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01375140Phase 2 · completed Ruxolitinib and Lenalidomide for Patients With Myelofibrosis · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02257138Phase 1/Phase 2 · completed Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia · 177 trials list this drug (74 active) | — | — | Myelodysplastic/Myeloproliferative Neoplasm,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02420717Phase 2 · terminated Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia · 177 trials list this drug (74 active) | — | — | B Acute Lymphoblastic Leukemia,B Acute Lymphoblastic Leukemia, BCR-ABL1-Like | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05440942Phase 1 · completed Combined MEK, STAT3 and PD-1 Inhibition in Metastatic Pancreatic Ductal Adenocarcinoma · 177 trials list this drug (74 active) | — | — | Pancreatic Ductal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01751425Phase 1 · terminated Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase Inhibitors · 177 trials list this drug (74 active) | — | — | Chronic Myeloid Leukemia, BCR-ABL1 Positive,Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02713386Phase 1/Phase 2 · completed Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · 177 trials list this drug (74 active) | — | — | Fallopian Tube Endometrioid Adenocarcinoma,Malignant Fallopian Tube Neoplasm,Primary Peritoneal Endometrioid Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01895842Phase 1 · completed Ruxolitinib for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) · 177 trials list this drug (74 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04041050Phase 1 · active not recruiting A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04281498Phase 2 · completed Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 Mutation · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06225310Phase 1 · recruiting A Trial of Selinexor, Ruxolitinib and Methylprednisolone · 177 trials list this drug (74 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03773107Phase 1/Phase 2 · completed LCI-HEM-MYE-CRD-004 (MMRC-073 CARJAK): Study of CRD for Carfilzomib-Refractory Multiple Myeloma · 177 trials list this drug (74 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04807777Phase 2 · terminated Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma · 177 trials list this drug (74 active) | — | — | Skin Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06209606early Phase 1 · recruiting Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma · 177 trials list this drug (74 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03153982Phase 2 · terminated Ruxolitinib in Operable Head and Neck Cancer · 177 trials list this drug (74 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04934670Phase 3 · terminated A Study to Compare T-Guard vs Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-vs-Host Disease (BMT CTN 2002) · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05870475Phase 2 · recruiting Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06477549Phase 2 · recruiting BeFluBu vs FluBuRux Conditioning in Haploidentical HCT · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Lymphoblastic Lymphoma,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01594216Phase 2 · completed Ruxolitinib in Estrogen Receptor Positive Breast Cancer · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02718300Phase 2 · terminated A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05663827Phase 3 · completed Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878524Phase 1 · terminated Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphatic System Neoplasm,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03012230Phase 1 · completed Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer · 177 trials list this drug (74 active) | — | — | Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02152956Phase 1/Phase 2 · terminated Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML) · 177 trials list this drug (74 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04055844Phase 2 · completed Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS · 177 trials list this drug (74 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03110822Phase 1 · recruiting A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients · 177 trials list this drug (74 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04303403Phase 1 · unknown Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma · 177 trials list this drug (74 active) | — | — | Malignant Colorectal Neoplasm,Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01712308Phase 2 · completed Sotatercept in Treating Patients With Myeloproliferative Neoplasm-Associated Myelofibrosis or Anemia · 177 trials list this drug (74 active) | — | — | Myelodysplastic/Myeloproliferative Neoplasm,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01431209Phase 2 · completed Ruxolitinib Phosphate to Treat Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma After Stem Cell Transplant · 177 trials list this drug (74 active) | — | — | Diffuse Large B-Cell Lymphoma,Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04480086Phase 1 · terminated Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02066532Phase 1/Phase 2 · completed Ruxolitinib in Combination With Trastuzumab in Metastatic HER2 Positive Breast Cancer · 177 trials list this drug (74 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01712659Phase 1/Phase 2 · terminated Ruxolitinib for Adult T-Cell Leukemia · 177 trials list this drug (74 active) | — | — | Leukemia,Adult T-Cell Leukemia/Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05413356Phase 2 · unknown Ruxolitinib for Newly Diagnosed Bronchiolitis Obliterans Syndrome · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05566535unknown Changes in QoL and Symptoms in Patients With Polycythemia Vera Receiving Ruxo in a Routine Clinical Practice · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01776723Phase 1/Phase 2 · completed A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04354727Phase 1/Phase 2 · withdrawn A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03144687Phase 2 · completed A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01981850Phase 2 · completed A Phase 2 Study of RO7490677 In Participants With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Polycythemia Vera,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02613598Phase 1 · completed Dose Escalation Study to Determine the Maximum Tolerated Dose of the Combination of Ruxolitinib and Bortezomib in Patients With Relapsed or Refractory Lymphoma · 177 trials list this drug (74 active) | — | — | Hodgkin Lymphoma,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02587598Phase 1/Phase 2 · terminated Study of INCB053914 in Subjects With Advanced Malignancies · 177 trials list this drug (74 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03123588Phase 2 · terminated Phase 2 Study of Ruxolitinib Versus Anagrelide in Subjects With Essential Thrombocythemia Who Are Resistant to or Intolerant of Hydroxyurea (RESET-272) · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01620216Phase 2 · terminated Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia,Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02038036Phase 3 · completed Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02041429Phase 1/Phase 2 · completed Ruxolitinib W/ Preop Chemo For Triple Negative Inflammatory Brca · 177 trials list this drug (74 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03041636Phase 2 · completed Ruxolitinib Phosphate in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma · 177 trials list this drug (74 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02973711Phase 1/Phase 2 · withdrawn A Study of Ruxolitinib in Combination With Nilotinib in Patients With Chronic Phase CML · 177 trials list this drug (74 active) | — | — | Chronic Myeloid Leukemia, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01702064Phase 1 · completed Ruxolitinib in Combination With Nilotinib in Chronic Myeloid Leukemia (CML) Patients · 177 trials list this drug (74 active) | — | — | Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02092324Phase 2 · completed Ruxolitinib Phosphate in Treating Patients With Chronic Neutrophilic Leukemia or Atypical Chronic Myeloid Leukemia · 177 trials list this drug (74 active) | — | — | Atypical Chronic Myeloid Leukemia,Chronic Neutrophilic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01914484Phase 1/Phase 2 · completed Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia · 177 trials list this drug (74 active) | — | — | Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03515200Phase 1 · terminated Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03669965Phase 2 · active not recruiting KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01369498Phase 2 · completed Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia Myelofibrosis · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04446806Phase 4 · unknown Prevention and Treatment of Differentiation Syndrome in Patients With Acute Promyelocytic Leukemia · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04016116Phase 2 · withdrawn Dual PD-1 and JAK2 Inhibition in Hematological Malignancies · 177 trials list this drug (74 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02779283Phase 1 · completed Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia · 177 trials list this drug (74 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01787552Phase 1/Phase 2 · completed A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm,Essential Thrombocythemia,Polycythemia Vera+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02164500Phase 2 · completed JAK-inhibition in Recurrent Classical Hodgkin Lymphoma · 177 trials list this drug (74 active) | — | — | Classic Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02638428Phase 2 · unknown Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy · 177 trials list this drug (74 active) | — | — | Childhood Solid Neoplasm,Childhood Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03558607Phase 1/Phase 2 · unknown The Role of Ruxolitinib in Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative Neoplasm · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01348490Phase 2 · completed Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF) · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02292446Phase 3 · completed Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available. · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02267278Phase 2 · completed Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF) · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02253277Phase 1 · completed Safety and Tolerability of Combined Treatment With Nilotinib and Ruxolitinib in CML and Ph+ ALL Patients · 177 trials list this drug (74 active) | — | — | Chronic Myeloid Leukemia, BCR-ABL1 Positive | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02117479Phase 3 · terminated Study of Ruxolitinib in Pancreatic Cancer Patients (Janus 1) · 177 trials list this drug (74 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01243944Phase 3 · completed Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial) · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02072057Phase 2 · terminated Study of Ruxolitinib in the Treatment of Cachexia in Patients With Tumor-Associated Chronic Wasting Diseases. · 177 trials list this drug (74 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02076191Phase 1/Phase 2 · completed Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02155465Phase 1/Phase 2 · completed Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib · 177 trials list this drug (74 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01965119Phase 2 · completed Pilot Study of Ruxolitinib in Relapsed or Refractory Hodgkin Lymphoma and Primary Mediastinal Large B-cell Lymphoma · 177 trials list this drug (74 active) | — | — | Hodgkin Lymphoma,Primary Mediastinal Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01877005Phase 2 · completed A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Classical Hodgkin's Lymphoma · 177 trials list this drug (74 active) | — | — | Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03613428Phase 1/Phase 2 · unknown Ruxolitinib Plus LVP in Patients With R/R ETP-ALL · 177 trials list this drug (74 active) | — | — | T Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00509899Phase 1/Phase 2 · completed Open Label Ruxolitinib (INCB018424) in Patients With Myelofibrosis and Post Polycythemia Vera/Essential Thrombocythemia Myelofibrosis · 177 trials list this drug (74 active) | — | — | Polycythemia Vera,Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00952289Phase 3 · completed COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial · 177 trials list this drug (74 active) | — | — | Myeloproliferative Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00639002Phase 2 · completed A Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor (Ruxolitinib; INBC018424) in Patients With Multiple Myeloma · 177 trials list this drug (74 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02119650Phase 2 · terminated Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer · 177 trials list this drug (74 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02119663Phase 3 · terminated A Study of Ruxolitinib in Pancreatic Cancer Patients · 177 trials list this drug (74 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02119676Phase 2 · terminated Study of Ruxolitinib in Colorectal Cancer Patients · 177 trials list this drug (74 active) | — | — | Colorectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02120417Phase 2 · terminated A Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast Cancer · 177 trials list this drug (74 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00638378Phase 2 · terminated Study of Ruxolitinib (INCB018424) Administered Orally to Patients With Androgen Independent Metastatic Prostate Cancer · 177 trials list this drug (74 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01423604Phase 2 · completed Study of Ruxolitinib in Pancreatic Cancer Patients · 177 trials list this drug (74 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01822756Phase 1 · terminated An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid Tumors · 177 trials list this drug (74 active) | — | — | Solid Neoplasm,Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01632904Phase 3 · completed Randomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief Study · 177 trials list this drug (74 active) | — | — | Polycythemia Vera | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02593929early Phase 1 · withdrawn Pharmacodynamic Effects and Predictive Biomarkers With Ruxolitinib in Operable Head and Neck Cancer · 177 trials list this drug (74 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02912754Phase 1/Phase 2 · unknown Ruxolitinib Combined With Ibrutinib in Chronic Lymphocytic Leukemia Patients · 177 trials list this drug (74 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01562873Phase 2 · terminated Ruxolitinib in Patients With Breast Cancer · 177 trials list this drug (74 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02015208Phase 1/Phase 2 · completed Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia · 177 trials list this drug (74 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02528877Phase 1 · withdrawn Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis · 177 trials list this drug (74 active) | — | — | Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia,Primary Myelofibrosis+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01164163Phase 1 · completed INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease · 177 trials list this drug (74 active) | — | — | Childhood Solid Neoplasm,Leukemia,Myelodysplastic Syndrome+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01340651Phase 2 · completed Study of Ruxolitinib (INCB018424) Sustained Release Formulation in Myelofibrosis Patients · 177 trials list this drug (74 active) | — | — | Primary Myelofibrosis | 1 | Observed | clinicaltrials | graph → |