| Rucaparib studied in …STUDIED_INderived60 of 60show fewer |
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| → studied in | NCT03899155Phase 2 · recruiting Pan Tumor Rollover Study · 60 trials list this drug (9 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03442556Phase 2 · terminated Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency · 60 trials list this drug (9 active) | — | — | Prostate Adenocarcinoma,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04209595Phase 1/Phase 2 · completed PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers · 60 trials list this drug (9 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03654833Phase 2 · completed Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma · 60 trials list this drug (9 active) | — | — | Malignant Mesothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03768063Phase 3 · active not recruiting A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study · 60 trials list this drug (9 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04624178Phase 2 · active not recruiting A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma · 60 trials list this drug (9 active) | — | — | Leiomyosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03694262Phase 2 · completed The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib) · 60 trials list this drug (9 active) | — | — | Uterine Carcinosarcoma,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02873962Phase 2 · active not recruiting A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03617679Phase 2 · completed Rucaparib vs Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer · 60 trials list this drug (9 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04539327completed Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study · 60 trials list this drug (9 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03559049Phase 1/Phase 2 · terminated Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer · 60 trials list this drug (9 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04455750Phase 3 · active not recruiting A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy · 60 trials list this drug (9 active) | — | — | Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03338790Phase 2 · completed An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer · 60 trials list this drug (9 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03542175Phase 1 · completed A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04276376Phase 2 · terminated Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors · 60 trials list this drug (9 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02711137Phase 1/Phase 2 · terminated Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies · 60 trials list this drug (9 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02975934Phase 3 · completed A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency · 60 trials list this drug (9 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03522246Phase 3 · active not recruiting A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy · 60 trials list this drug (9 active) | — | — | Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02678182Phase 2 · active not recruiting Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial · 60 trials list this drug (9 active) | — | — | Gastric Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03639935Phase 2 · completed Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy · 60 trials list this drug (9 active) | — | — | Malignant Biliary Tract Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03845296Phase 2 · completed Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) · 60 trials list this drug (9 active) | — | — | Malignant Lung Neoplasm,Lung Large Cell Carcinoma,Lung Non-Small Cell Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04253262Phase 1/Phase 2 · active not recruiting A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer · 60 trials list this drug (9 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03552471Phase 1 · completed Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer · 60 trials list this drug (9 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Endometrial Serous Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04826198Phase 1/Phase 2 · terminated Safety and Efficacy of AsiDNATM, a DNA Repair Inhibitor, Administered Intravenously in Addition to PARP Inhibitors in Patients With Relapsed Platinum Sensitive Ovarian Cancer Already Treated With PARP Inhibitors Since at Least 6 Months · 60 trials list this drug (9 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04227522Phase 3 · completed Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients · 60 trials list this drug (9 active) | — | — | Clear Cell Adenocarcinoma,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03413995Phase 2 · completed Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations · 60 trials list this drug (9 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03911453early Phase 1 · completed Window of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast Tumors · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01074970Phase 2 · completed PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03337087Phase 1/Phase 2 · unknown Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer · 60 trials list this drug (9 active) | — | — | Malignant Digestive System Neoplasm,Biliary Tract Carcinoma,Colorectal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04676334Phase 3 · completed CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03533946Phase 2 · terminated Rucaparib in Nonmetastatic prOstAte With BRCAness · 60 trials list this drug (9 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03476798Phase 2 · completed Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium · 60 trials list this drug (9 active) | — | — | Malignant Cervical Neoplasm,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02925234Phase 2 · recruiting The Drug Rediscovery Protocol (DRUP Trial) · 60 trials list this drug (9 active) | — | — | Neoplasm,Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03992131Phase 1/Phase 2 · terminated A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR) · 60 trials list this drug (9 active) | — | — | Solid Neoplasm,Malignant Ovarian Neoplasm,Urothelial Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03840200Phase 1 · completed A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer. · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm,Malignant Ovarian Neoplasm,Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04171700Phase 2 · terminated A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes · 60 trials list this drug (9 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03140670Phase 2 · terminated Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy · 60 trials list this drug (9 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04179396Phase 1 · completed Study of Oral Rucaparib With Other Anticancer Agents in Metastatic Castration Resistant Prostate Cancer Patients (RAMP) · 60 trials list this drug (9 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02042378Phase 2 · completed A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation · 60 trials list this drug (9 active) | — | — | Malignant Pancreatic Neoplasm,Pancreatic Ductal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01891344Phase 2 · completed A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2) · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03824704Phase 2 · terminated A Study to Evaluate Rucaparib in Combination With Nivolumab in Patients With Selected Solid Tumors (ARIES) · 60 trials list this drug (9 active) | — | — | Endometrioid Adenocarcinoma,Primary Peritoneal Carcinoma,Malignant Fallopian Tube Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01482715Phase 1/Phase 2 · completed A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II) · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01968213Phase 3 · completed Phase 3 Study of Rucaparib as Switch Maintenance After Platinum in Relapsed High Grade Serous or Endometrioid Ovarian Cancer (ARIEL3) · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02740712Phase 1 · completed Pharmacokinetic Drug-Drug Interaction Study of Rucaparib · 60 trials list this drug (9 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02855944Phase 3 · completed ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients · 60 trials list this drug (9 active) | — | — | Malignant Peritoneal Neoplasm,Malignant Fallopian Tube Neoplasm,Malignant Ovarian Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02935634Phase 2 · completed A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer · 60 trials list this drug (9 active) | — | — | Malignant Gastric Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02952534Phase 2 · completed A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency · 60 trials list this drug (9 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02986100Phase 1 · completed Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib · 60 trials list this drug (9 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03397394Phase 2 · terminated Rucaparib in Patients With Locally Advanced or Metastatic Urothelial Carcinoma · 60 trials list this drug (9 active) | — | — | Urothelial Carcinoma,Malignant Bladder Neoplasm,Renal Pelvis Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03499444Phase 1 · completed A Study of Rucaparib in Japanese Patients With a Previously-treated Solid Tumor · 60 trials list this drug (9 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03521037Phase 1 · completed Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor · 60 trials list this drug (9 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03954366Phase 1 · completed Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives · 60 trials list this drug (9 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03995017Phase 1/Phase 2 · unknown Rucaparib Plus Ramucirumab With or Without Nivolumab in Advanced Gastric and Esophageal Adenocarcinoma · 60 trials list this drug (9 active) | — | — | Malignant Gastric Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03462212Phase 1/Phase 2 · unknown Carboplatin-Paclitaxel-Bevacizumab vs Carbo-Pacli-Beva-Rucaparib vs Carbo-Pacli-Ruca, Selected According to HRD Status, in Patients With Advanced Ovarian, Primary Peritoneal and Fallopian Tube Cancer, Preceded by a Phase I Dose Escalation Study on Ruca-Beva Combination · 60 trials list this drug (9 active) | — | — | Fallopian Tube Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02505048Phase 2 · completed A Study to Assess the Efficacy of Rucaparib in Metastatic Breast Cancer Patients With a BRCAness Genomic Signature · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03572478Phase 1/Phase 2 · terminated Rucaparib and Nivolumab in Patients With Prostate or Endometrial Cancer · 60 trials list this drug (9 active) | — | — | Malignant Prostate Neoplasm,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03318445Phase 1 · completed Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair · 60 trials list this drug (9 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03101280Phase 1 · completed A Combination Study of Rucaparib and Atezolizumab in Participants With Advanced Gynecologic Cancers and Triple-Negative Breast Cancer · 60 trials list this drug (9 active) | — | — | Female Reproductive System Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03795272Phase 2 · withdrawn Rucaparib Maintenance Therapy in Advanced Cervical Cancer · 60 trials list this drug (9 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00664781Phase 2 · completed Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer · 60 trials list this drug (9 active) | — | — | Malignant Breast Neoplasm,Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |