| Pegargiminase studied in …STUDIED_INderived33 of 33show fewer |
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| → studied in | NCT06085729Phase 1/Phase 2 · recruiting Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC) · 33 trials list this drug (6 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07389278Phase 1/Phase 2 · not yet recruiting Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG) · 33 trials list this drug (6 active) | — | — | Glioblastoma,Glioma,Diffuse Midline Glioma, H3 K27M-Mutant+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05813327Phase 1 · terminated Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma · 33 trials list this drug (6 active) | — | — | Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03970447Phase 2/Phase 3 · recruiting A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma · 33 trials list this drug (6 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05616624Phase 1/Phase 2 · terminated ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers · 33 trials list this drug (6 active) | — | — | Lung Non-Small Cell Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05712694Phase 3 · terminated Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC) · 33 trials list this drug (6 active) | — | — | Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05001828Phase 1 · active not recruiting Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia · 33 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05317819Phase 3 · recruiting Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03449901Phase 2 · completed ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer · 33 trials list this drug (6 active) | — | — | Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04587830Phase 2 · active not recruiting ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme · 33 trials list this drug (6 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03922880Phase 1 · completed Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma · 33 trials list this drug (6 active) | — | — | Uveal Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06006286Phase 1/Phase 2 · withdrawn A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06034977Phase 2 · unknown Phase 2 Study of ADI-PEG 20 Plus Lenvatinib Treatment in Subjects With Unresectable Hepatocellular Carcinoma · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04965714Phase 2 · withdrawn Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00520299Phase 1/Phase 2 · completed Study of ADI-PEG 20 in Patients With Advanced Melanoma · 33 trials list this drug (6 active) | — | — | Neoplasm,Malignant Skin Neoplasm,Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01266018Phase 2 · terminated Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer · 33 trials list this drug (6 active) | — | — | Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03254732Phase 1 · terminated Study ADI-PEG 20 Plus Pembrolizumab in Advanced Solid Cancers · 33 trials list this drug (6 active) | — | — | Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01910012Phase 2 · completed PH 2 ADI-PEG 20 Acute Myeloid Leukemia · 33 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02101580Phase 1 · completed Ph 1B Trial With ADI-PEG 20 Plus Nab-Paclitaxel and Gemcitabine in Subjects With Pancreatic Cancer · 33 trials list this drug (6 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02029690Phase 1 · terminated Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin · 33 trials list this drug (6 active) | — | — | Glioma,Sarcomatoid Carcinoma,Uveal Melanoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02875093Phase 1 · terminated Ph 1 Study of ADI-PEG 20 Plus Low Dose Cytarabine in Older Patients With AML · 33 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03498222Phase 1 · withdrawn Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin · 33 trials list this drug (6 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01287585Phase 3 · completed Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01910025Phase 2 · completed PH 2 ADI-PEG 20 Study in Non-Hodgkin's Lymphoma Subjects Who Have Failed Prior Systemic Therapy · 33 trials list this drug (6 active) | — | — | Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01497925Phase 1 · completed Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer · 33 trials list this drug (6 active) | — | — | Solid Neoplasm,Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02006030Phase 2 · completed Ph 2 Trial of ADI PEG 20 Plus Concurrent Transarterial Chemoembolization (TACE) Vs TACE Alone in Patients With Unresectable Hepatocellular Carcinoma · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00450372Phase 2 · completed Pegylated Arginine Deiminase in Treating Patients With Metastatic Melanoma That Cannot Be Removed by Surgery · 33 trials list this drug (6 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01948843Phase 1 · completed Ph 1 ADI-PEG 20 Plus Doxorubicin; Patients With HER2 Negative Metastatic Breast Cancer · 33 trials list this drug (6 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02101593Phase 1 · completed Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01665183Phase 1 · completed Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma · 33 trials list this drug (6 active) | — | — | Cutaneous Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00029900Phase 1 · completed ADI-PEG in Patients With Metastatic Melanoma · 33 trials list this drug (6 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00056992Phase 2 · completed Testing of ADI-PEG in Hepatocellular Carcinoma · 33 trials list this drug (6 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01279967Phase 2 · unknown A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma · 33 trials list this drug (6 active) | — | — | Pleural Malignant Mesothelioma | 1 | Observed | clinicaltrials | graph → |