| Midostaurin studied in …STUDIED_INderived43 of 43show fewer |
|---|
| → studied in | NCT03836209Phase 2 · completed Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03591510Phase 2 · active not recruiting A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML · 43 trials list this drug (6 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02115295Phase 2 · recruiting Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03900949Phase 1 · completed Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03258931Phase 3 · completed Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML · 43 trials list this drug (6 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00819546Phase 1 · active not recruiting RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS · 43 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06313437Phase 1 · recruiting Revumenib in Combination With 7+3 + Midostaurin in AML · 43 trials list this drug (6 active) | — | — | Leukemia,Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03280030Phase 2 · completed A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03686345Phase 2 · terminated Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia · 43 trials list this drug (6 active) | — | — | Core Binding Factor Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03092674Phase 2/Phase 3 · completed Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome · 43 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia,Myelodysplastic Syndrome/Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04027309Phase 3 · active not recruiting A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia,Myelodysplastic Syndrome/Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04982354Phase 1/Phase 2 · withdrawn Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04097470Phase 2 · active not recruiting Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05219266no longer available Managed Access Programs for PKC412, Midostaurin · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia,Aggressive Systemic Mastocytosis,Mast Cell Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03379727Phase 3 · completed Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia. · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04075747Phase 1 · completed A Phase 1b Master Trial to Investigate CPX-351 in Subjects With Previously Untreated Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03512197Phase 3 · completed A Global Study of the Efficacy and Safety of Midostaurin + Chemotherapy in Newly Diagnosed Patients With FLT3 Mutation Negative (FLT3-MN) Acute Myeloid Leukemia (AML) · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05488613completed Healthcare Resource Utilization in Adults Diagnosed With Acute Myeloid Leukemia (AML) · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04496999Phase 1 · terminated HDM201 and Midostaurin (HDMM) in Relapsed/Refractory AML With FLT3mut and TP53wt. · 43 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01093573Phase 1/Phase 2 · completed Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia · 43 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04174612Phase 3 · unknown AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia with FLT3/ITD Mutation | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03951961Phase 2 · terminated Midostaurin in MRD (Minimal Residual Disease) Positive Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation · 43 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00651261Phase 3 · unknown Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01883362Phase 2 · completed Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00093600Phase 1 · completed PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01830361Phase 2 · completed Trial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AML · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02624570no longer available Midostaurin Access Program for Newly Diagnosed FLT3 (ITD or TKD) Mutated AML Adult Patients Eligible for Standard Induction and Consolidation Chemotherapy · 43 trials list this drug (6 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01477606Phase 2 · completed Protocol in Acute Myeloid Leukemia With FLT3-ITD · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03760445Phase 1/Phase 2 · withdrawn HDM201 Added to CT in R/R or Newly Diagnosed AML · 43 trials list this drug (6 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03114228no longer available An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML) · 43 trials list this drug (6 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02634827Phase 2 · terminated Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation · 43 trials list this drug (6 active) | — | — | Secondary Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia,Acute Myeloid Leukemia with FLT3/ITD Mutation | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01282502Phase 1 · completed Midostaurin (PKC412) for Locally Advanced Rectal Cancer · 43 trials list this drug (6 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00782067Phase 2 · completed Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia · 43 trials list this drug (6 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03207334Phase 2 · withdrawn iCare4: Genomic Signatures With Midostaurin in Acute Myeloid Leukemia (UF-HEM-004) · 43 trials list this drug (6 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01202877Phase 1/Phase 2 · completed PKC412 and 5-Azacytidine · 43 trials list this drug (6 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01846624Phase 2 · terminated Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia,Acute Myeloid Leukemia with del(5q) | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00233454Phase 2 · completed Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia · 43 trials list this drug (6 active) | — | — | Mast Cell Leukemia,Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02723435Phase 2 · withdrawn Midostaurin in Treating Older Patients With Mutated Acute Myeloid Leukemia Post-Transplant · 43 trials list this drug (6 active) | — | — | Adult Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00045942Phase 1/Phase 2 · completed PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2) · 43 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01174888Phase 1 · completed Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia · 43 trials list this drug (6 active) | — | — | Myelodysplastic Syndrome,Secondary Acute Myeloid Leukemia,Acute Myeloid Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00866281Phase 1/Phase 2 · terminated A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia · 43 trials list this drug (6 active) | — | — | Acute Lymphoblastic Leukemia,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01920204Phase 2 · unknown Midostaurin in Indolent Systemic Mastocytosis · 43 trials list this drug (6 active) | — | — | Indolent Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01161550Phase 1 · completed Cladribine Based Induction Therapy With All-Trans Retinoic Acid and Midostaurin in Relapsed/Refractory AML · 43 trials list this drug (6 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |