Gene
PRKCE
protein kinase C epsilon
Explore in graph →CI-GENE-00020997HGNC:9401 ENSG00000171132 NCBI 5581 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 2 | 4 | 50% | 59 | cbioportal |
| Triple-Negative Breast Cancer (FUSCC, Cell Research 2020) brca_fuscc_2020 | Invasive Breast Carcinoma | Ssm | 3 | 69 | 4.3% | 55 | cbioportal |
| Lung Adenocarcinoma (TSP, Nature 2008) luad_tsp | Lung Adenocarcinoma | Ssm | 3 | 163 | 1.8% | 86 | cbioportal |
| Breast Cancer (METABRIC, Nature 2012 & Nat Commun 2016) brca_metabric | Invasive Breast Carcinoma | Ssm | 20 | 2,433 | 0.8% | 125 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.