| Metformin studied in …STUDIED_INderived200 of 372show all (up to 200) |
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| → studied in | NCT07585396Phase 2/Phase 3 · completed Inositol in Letrozol Resistant PCOS Women · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05237960Phase 2 · active not recruiting Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02365597Phase 2 · active not recruiting An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05183204Phase 2 · completed Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma · 372 trials list this drug (57 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02040376Phase 3 · completed Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma · 372 trials list this drug (57 active) | — | — | Medulloblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05230758Phase 3 · recruiting Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour · 372 trials list this drug (57 active) | — | — | Childhood Medulloblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07815808Phase 3 · not yet recruiting Cardioprotective Effect of Empagliflozin in Breast Cancer Patients · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03424005Phase 1/Phase 2 · recruiting A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07811856Phase 4 · completed Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03006172Phase 1 · active not recruiting To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer · 372 trials list this drug (57 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06899061Phase 1 · active not recruiting Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04925063Phase 2 · active not recruiting The Effect of Metformin in Patients With Newly Diagnosed mHSPC · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07793838Phase 4 · completed Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05965908Phase 3 · completed Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07226453Phase 2 · recruiting Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07770711NA · not yet recruiting Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07372625Phase 1 · recruiting A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation. · 372 trials list this drug (57 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07759674Phase 4 · completed Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07188740Phase 1 · recruiting Metformin Inhibits DNMT3A Clonal Hematopoiesis in Acute Leukemia · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00038727Phase 3 · completed Diabetes Prevention Program Outcomes Study · 372 trials list this drug (57 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01797523Phase 2 · completed A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma · 372 trials list this drug (57 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03031821Phase 3 · terminated Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07098299Phase 1 · recruiting Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies · 372 trials list this drug (57 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07291297Phase 2 · recruiting Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma · 372 trials list this drug (57 active) | — | — | Sarcoma,Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01750567Phase 2 · completed A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL · 372 trials list this drug (57 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02967276Phase 2 · terminated Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma · 372 trials list this drug (57 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06377696Phase 2 · recruiting Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy · 372 trials list this drug (57 active) | — | — | Malignant Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02186847Phase 2 · completed Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer · 372 trials list this drug (57 active) | — | — | Lung Large Cell Carcinoma,Lung Non-Small Cell Carcinoma,Lung Squamous Cell Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07693452Phase 2 · recruiting Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms · 372 trials list this drug (57 active) | — | — | Appendix Mucinous Neoplasm,Pseudomyxoma Peritonei | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05768139Phase 1/Phase 2 · recruiting First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors · 372 trials list this drug (57 active) | — | — | Adult Solid Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07687667NA · not yet recruiting Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03311308Phase 1 · active not recruiting A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma · 372 trials list this drug (57 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02581137Phase 2 · active not recruiting Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion · 372 trials list this drug (57 active) | — | — | Oral Cavity Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04114136Phase 2 · recruiting Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies · 372 trials list this drug (57 active) | — | — | Melanoma,Head and Neck Squamous Cell Carcinoma,Hepatocellular Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04536805Phase 1/Phase 2 · active not recruiting Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07399535Phase 1 · completed Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03675893Phase 2 · recruiting RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer · 372 trials list this drug (57 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07603505Phase 1 · completed Effect of NAE on Polycystic Ovarian Syndrome (PCOS) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06763328Phase 3 · recruiting Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy · 372 trials list this drug (57 active) | — | — | Invasive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04621669Phase 1 · completed Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07628556completed Antidiabetic Medications and Risk of Cancer · 372 trials list this drug (57 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05515978early Phase 1 · recruiting Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06405178Phase 3 · completed Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02755844Phase 1/Phase 2 · completed Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients · 372 trials list this drug (57 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07604870Phase 2 · completed Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04414540Phase 2 · active not recruiting Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients · 372 trials list this drug (57 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04742751Phase 2 · active not recruiting An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01905046Phase 3 · active not recruiting Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer · 372 trials list this drug (57 active) | — | — | Breast Lobular Carcinoma In Situ,Breast Atypical Ductal Hyperplasia,Breast Ductal Carcinoma In Situ | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02874430Phase 2 · terminated Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer · 372 trials list this drug (57 active) | — | — | Breast Carcinoma,Uterine Corpus Carcinosarcoma,Endometrial Serous Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05966792NA · completed SGLT2 Inhibitors in Treating Patients With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05445791Phase 3 · recruiting Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations · 372 trials list this drug (57 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02437656Phase 2 · completed Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer. · 372 trials list this drug (57 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02122185Phase 2 · completed Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · 372 trials list this drug (57 active) | — | — | Ovarian Germ Cell Tumor,Brenner Tumor,Malignant Fallopian Tube Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07459595Phase 1 · not yet recruiting Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02946996Phase 2 · terminated Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03905941early Phase 1 · withdrawn Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04850846Phase 2 · active not recruiting Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma · 372 trials list this drug (57 active) | — | — | Smoldering Multiple Myeloma,Monoclonal Gammopathy of Undetermined Significance | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05767515NA · completed The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07387900Phase 2 · recruiting Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02336087Phase 1 · active not recruiting Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery · 372 trials list this drug (57 active) | — | — | Pancreatic Carcinoma,Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07387679NA · completed Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07380841NA · completed Metformin vs Inositol vs Diet vs Combination Therapy in PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03076281Phase 2 · terminated Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04576104Phase 2 · active not recruiting Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer · 372 trials list this drug (57 active) | — | — | Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia,Endometrial Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06044025Phase 1 · recruiting A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07323589Phase 3 · completed Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05023967Phase 2 · active not recruiting Metformin and Nightly Fasting in Women With Early Breast Cancer · 372 trials list this drug (57 active) | — | — | Breast Ductal Carcinoma In Situ,Invasive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04691960Phase 2 · active not recruiting A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging · 372 trials list this drug (57 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03109847Phase 2 · terminated Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04945148Phase 2 · recruiting Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide · 372 trials list this drug (57 active) | — | — | Glioblastoma, IDH-Wildtype | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03889795Phase 1 · active not recruiting Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors · 372 trials list this drug (57 active) | — | — | Solid Neoplasm,Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04931017Phase 2 · active not recruiting Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer · 372 trials list this drug (57 active) | — | — | Lung Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06479434NA · completed Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05680805Phase 4 · active not recruiting Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07182526Phase 2 · recruiting Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07120815Phase 3 · not yet recruiting Optimizing Metformin Use in Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06728982Phase 2/Phase 3 · completed Impact Of Metformin In Rectal Cancer Patients · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04300790Phase 2 · completed Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05929495Phase 2 · recruiting Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma · 372 trials list this drug (57 active) | — | — | Glioblastoma, IDH-Wildtype | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06687876Phase 2 · recruiting Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02500147Phase 4 · terminated Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02780024Phase 2 · active not recruiting Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM · 372 trials list this drug (57 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01697566Phase 3 · completed An Endometrial Cancer Chemoprevention Study of Metformin · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06742710Phase 4 · recruiting Liraglutide Treatment in Obese Infertile PCOS Women · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02083692early Phase 1 · completed Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03618654early Phase 1 · completed Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma · 372 trials list this drug (57 active) | — | — | Head and Neck Squamous Cell Carcinoma,Oral Cavity Squamous Cell Carcinoma,Oropharyngeal Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05536037Phase 1 · terminated Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions · 372 trials list this drug (57 active) | — | — | Oral Cavity Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06140108Phase 2/Phase 3 · completed Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01430351Phase 1 · terminated Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy · 372 trials list this drug (57 active) | — | — | Glioblastoma,Gliosarcoma,Supratentorial Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02339168Phase 1 · completed Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03109873early Phase 1 · completed Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02521753NA · terminated Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05828303Phase 1 · withdrawn A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors · 372 trials list this drug (57 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01529593Phase 1 · terminated Temsirolimus in Combination With Metformin in Patients With Advanced Cancers · 372 trials list this drug (57 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06884683Phase 2 · terminated Nivolumab Plus Metformin in Metastatic Renal Cell Carcinoma · 372 trials list this drug (57 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04116203Phase 1 · completed Dietary Fish Oil Intervention in Polycystic Ovary Syndrome (PCOS) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04947020completed DataBase for Analysis of Rectal Cancer Oncological Results · 372 trials list this drug (57 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05158374NA · withdrawn Molecular Effects of Aspirin & Metformin on Colonic Epithelium · 372 trials list this drug (57 active) | — | — | Colorectal Adenoma,Colorectal Neoplasm,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02488564Phase 2 · completed A Study of Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04275713Phase 2 · completed Altered Tumor Oxygenation by Metformin, a Potential Step in Overcoming Radiotherapy Resistance in LACC · 372 trials list this drug (57 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06353061Phase 2 · unknown Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer · 372 trials list this drug (57 active) | — | — | Malignant Cervical Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06775093NA · not yet recruiting Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06125587Phase 2/Phase 3 · completed Chiglitazar/Metformin in Non-obese Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02035787Phase 2 · completed Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients · 372 trials list this drug (57 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03618472NA · completed Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04741945Phase 2 · recruiting Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS · 372 trials list this drug (57 active) | — | — | Myelodysplastic Syndrome | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04836910not yet recruiting Microbiome and Polycystic Ovaries · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03378297early Phase 1 · completed IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC · 372 trials list this drug (57 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06576375Phase 3 · unknown Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02647827Phase 2 · recruiting Acupuncture or Metformin for Insulin Resistance in Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04899349Phase 2 · terminated Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05854966Phase 2 · withdrawn CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) · 372 trials list this drug (57 active) | — | — | Granulocytic Sarcoma,Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03800602Phase 2 · completed Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer · 372 trials list this drug (57 active) | — | — | Colorectal Neoplasm,Colorectal Adenocarcinoma,Colorectal Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01686126Phase 2 · active not recruiting Improving the Treatment for Women With Early Stage Cancer of the Uterus · 372 trials list this drug (57 active) | — | — | FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02431676Phase 2 · completed Survivorship Promotion In Reducing IGF-1 Trial · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm,Cutaneous Melanoma,Malignant Lung Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03829020Phase 1 · completed Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma · 372 trials list this drug (57 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06215976Phase 4 · unknown The Nephroprotective Effect of Metformin With Cisplatin in Bladder Cancer · 372 trials list this drug (57 active) | — | — | Muscle Invasive Bladder Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06537843Phase 2 · recruiting Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia · 372 trials list this drug (57 active) | — | — | Acute Myeloid Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05646199Phase 2/Phase 3 · unknown Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02312661Phase 1 · completed Study of Metformin With Carboplatin/Paclitaxel Chemotherapy in Patients With Advanced Ovarian Cancer · 372 trials list this drug (57 active) | — | — | Ovarian Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02523898Phase 2 · terminated Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05394142Phase 2 · unknown A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05702905Phase 4 · unknown Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04593459Phase 4 · completed Probiotic Intervention in PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06325956NA · unknown PCOS Immune Function Predicts Metformin Efficacy · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04892186NA · completed Effects of Myo-inositol in Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06256289Phase 4 · unknown Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05986838NA · unknown Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05921942Phase 3 · completed The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer · 372 trials list this drug (57 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00984490NA · terminated Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01996696Phase 2 · terminated Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate · 372 trials list this drug (57 active) | — | — | Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01864096Phase 3 · unknown The Metformin Active Surveillance Trial (MAST) Study · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06170463Phase 1 · completed Insulin Sensitizers Role in Control of PCOS Vicious Cycle. · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02143050Phase 1/Phase 2 · withdrawn Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients · 372 trials list this drug (57 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05386706NA · completed Treating PCOS With Digital Intervention vs. Metformin · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01422746early Phase 1 · unknown Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05952882Phase 3 · unknown Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03017833Phase 1 · completed Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers · 372 trials list this drug (57 active) | — | — | Neoplasm,Malignant Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03477162early Phase 1 · terminated Metformin Pharmacology in Human Cancers: A Proof of Principle Study · 372 trials list this drug (57 active) | — | — | Thoracic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04033107Phase 2 · unknown High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors · 372 trials list this drug (57 active) | — | — | Malignant Gastric Neoplasm,Malignant Pancreatic Neoplasm,Hepatocellular Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06049186NA · unknown CRD vs. Met in Patients With Obese PCOS Infertility · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03379909Phase 2 · recruiting Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer · 372 trials list this drug (57 active) | — | — | Malignant Bladder Neoplasm,Non-Muscle Invasive Bladder Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01101438Phase 3 · completed A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01980823early Phase 1 · completed Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer · 372 trials list this drug (57 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06015594NA · completed Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice. · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05981742Phase 2 · completed Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04758000Phase 2 · recruiting Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse · 372 trials list this drug (57 active) | — | — | Ewing Sarcoma,Osteosarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04741204Phase 4 · withdrawn Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02949700Phase 1/Phase 2 · completed Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma · 372 trials list this drug (57 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02028221Phase 2 · completed Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02640534Phase 2 · terminated Investigation of Metformin in Patients With Castration Resistant Prostate Cancer in Combination With Enzalutamide vs. Enzalutamide Alone · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05840068Phase 4 · completed IGF Level in Breast Cancer Patients Treated With Metformin · 372 trials list this drug (57 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00268476Phase 2/Phase 3 · active not recruiting Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04792749Phase 3 · unknown Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer · 372 trials list this drug (57 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05351021Phase 2 · completed Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05759312Phase 1/Phase 2 · unknown Zimberelimab Plus Metformin for Recurrent Ovarian Clear Cell Carcinoma · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02420652Phase 2 · terminated Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm,Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04248998Phase 2 · unknown Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer · 372 trials list this drug (57 active) | — | — | Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01528046Phase 1 · completed Metformin in Children With Relapsed or Refractory Solid Tumors · 372 trials list this drug (57 active) | — | — | Solid Neoplasm,Primary Brain Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03200015Phase 2 · completed Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell Lymphoma · 372 trials list this drug (57 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00930579Phase 2 · completed Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05468554Phase 3 · unknown Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer · 372 trials list this drug (57 active) | — | — | Malignant Thyroid Gland Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02176161Phase 2 · completed Metformin Prostate Cancer Adjuvant Trial · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02446834NA · completed Research of Intensive Lifestyle Intervention for PCOS Patients With IGT · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02531308Phase 2 · terminated Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL) · 372 trials list this drug (57 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04170465Phase 2 · completed Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04700839Phase 4 · completed SGLT2 Inhibitors in Patients With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05519813Phase 4 · unknown Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients. · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02278965Phase 1 · completed Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer · 372 trials list this drug (57 active) | — | — | Breast Neoplasm,Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04428086Phase 1 · completed A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects. · 372 trials list this drug (57 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05463627unknown Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04973891Phase 1/Phase 2 · completed CANA/Met in Non-diabetic Women With PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02945813Phase 2 · terminated SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04969627Phase 4 · completed Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia. · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05326984NA · unknown Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia · 372 trials list this drug (57 active) | — | — | Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01929811Phase 2 · terminated NeoMET Study in Neoadjuvant Treatment of Breast Cancer · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05292573Phase 3 · unknown Longitudinal Follow-up in Women With Endometrial Hyperplasia Without Atypia · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02491333Phase 3 · completed The RCT of Acupuncture on PCOS Combined With IR · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01482286Phase 3 · terminated Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03359681Phase 2 · completed Metformin Treatment for Colon Cancer · 372 trials list this drug (57 active) | — | — | Malignant Colon Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05200793Phase 4 · unknown Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03238495Phase 2 · unknown Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer · 372 trials list this drug (57 active) | — | — | HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03510390NA · completed Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation · 372 trials list this drug (57 active) | — | — | Malignant Head and Neck Neoplasm,Oral Cavity Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01638676Phase 1/Phase 2 · recruiting A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients · 372 trials list this drug (57 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02065687Phase 2/Phase 3 · unknown Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer · 372 trials list this drug (57 active) | — | — | Endometrial Adenocarcinoma,Endometrial Serous Adenocarcinoma,Endometrial Undifferentiated Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05053841Phase 2 · completed Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer Women · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01725490Phase 2 · completed The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01666730Phase 2 · completed Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer · 372 trials list this drug (57 active) | — | — | Malignant Pancreatic Neoplasm,Pancreatic Neoplasm,Pancreatic Acinar Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04780854Phase 2 · unknown Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN) · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04926155Phase 2 · unknown The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01210911Phase 2 · completed Metformin Combined With Chemotherapy for Pancreatic Cancer · 372 trials list this drug (57 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02394652Phase 2 · completed The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial · 372 trials list this drug (57 active) | — | — | Adenocarcinoma,Squamous Cell Carcinoma,Adenosquamous Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02497638Phase 2 · withdrawn LIpitor and biGuanide to Androgen Delay Trial · 372 trials list this drug (57 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01310231Phase 2 · completed A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer · 372 trials list this drug (57 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02048384Phase 1 · completed A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer · 372 trials list this drug (57 active) | — | — | Pancreatic Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04268563Phase 1/Phase 2 · unknown Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02948283Phase 1 · completed Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia · 372 trials list this drug (57 active) | — | — | Multiple Myeloma,Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02495103Phase 1/Phase 2 · terminated Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma · 372 trials list this drug (57 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04170959Phase 2 · terminated The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC · 372 trials list this drug (57 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01427595NA · completed Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone · 372 trials list this drug (57 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |