Clinical trial · Interventional
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice. Results From a Single Center 5-years Retrospective Clinical Study
NCT06015594CI-TRIAL-00069139completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aimed to understand whether metformin therapy can improve insulin resistance in adolescent PCOS patients, both during treatment and after discontinuation, and to evaluate its action on the hormonal and metabolic pathways.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Metformin | Drug | Metformin | ALIAS |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Metformin group
- description
- Treated with metformin
- interventionNames
- Drug: Metformin
- type
- NO_INTERVENTION
- label
- Control group
- description
- not treated
Primary outcomes (2)
- measure
- Insulin resistance change in eighty hyperinsulinemic patients after metformin therapy and its discontinuation
- timeFrame
- about 3 years
- description
- To verify metformin treatment's immediate and long-term efficacy in hyperinsulinemic adolescent patients with PCOS and the evolution of metabolic status after treatment discontinuation.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 10 Years
- Maximum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: Pcos Adolescents \- Exclusion Criteria: Other type of hyperandrogenism
References
Publications (0)
Data not yet available
No reference posted for this study.