Prostate Neoplasm

Curated

← investigated for

Triptorelinother

unknown

Curated

← investigated for

Relugolixsmall_molecule

unknown

Curated

← investigated for

Radium Ra-223 Dichloridesmall_molecule

unknown

Curated

← investigated for

Radium Ra223 dichloridesmall_molecule

unknown

Curated

← investigated for

Padeliporfinsmall_molecule

unknown

Curated

← investigated for

Nilutamidesmall_molecule

unknown

Curated

← investigated for

Mitoxantronesmall_molecule

unknown

Curated

← investigated for

Leuprolideother

unknown

Curated

← investigated for

Histrelinother

unknown

Curated

← investigated for

Flutamidesmall_molecule

unknown

Curated

← investigated for

Enzalutamidesmall_molecule

unknown

Curated

← investigated for

Docetaxelsmall_molecule

unknown

Curated

← investigated for

Degarelixother

unknown

Curated

← investigated for

Darolutamidesmall_molecule

unknown

Curated

← investigated for

Cabazitaxelsmall_molecule

unknown

Curated

← investigated for

Apalutamidesmall_molecule

unknown

Curated

← investigated for

Abiraterone Acetatesmall_molecule

unknown

Curated

← investigated for

Sunitinibsmall_molecule

unknown

Curated

← investigated for

Rucaparibsmall_molecule

unknown

Curated

← investigated for

Prednisonesmall_molecule

unknown

Curated

← investigated for

Prednisolonesmall_molecule

unknown

Curated

← investigated for

Pembrolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Olaparibsmall_molecule

unknown

Curated

← investigated for

Meloxicamsmall_molecule

unknown

Curated

← investigated for

Lutetium (177lu) Vipivotide Tetraxetanother

unknown

Curated

← investigated for

Ipatasertibsmall_molecule

unknown

Curated

← investigated for

Goserelinother

unknown

Curated

← investigated for

Estramustinesmall_molecule

unknown

Curated

← investigated for

Dexamethasonesmall_molecule

unknown

Curated

← investigated for

Dasatinibsmall_molecule

unknown

Curated

← investigated for

Cyproterone Acetatesmall_molecule

unknown

Curated

← investigated for

Buserelinother

unknown

Curated

← investigated for

Bicalutamidesmall_molecule

unknown

Curated

← investigated for

Bevacizumabmonoclonal_antibody

unknown

Curated

← investigated for

Atezolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Abirateronesmall_molecule

unknown

Curated

← investigated for

Vorinostatsmall_molecule

unknown

Curated

← investigated for

Veliparibsmall_molecule

unknown

Curated

← investigated for

Vandetanibsmall_molecule

unknown

Curated

← investigated for

Tretinoinsmall_molecule

unknown

Curated

← investigated for

Tremelimumabmonoclonal_antibody

unknown

Curated

← investigated for

Trastuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Trametinibsmall_molecule

unknown

Curated

← investigated for

Tislelizumabmonoclonal_antibody

unknown

Curated

← investigated for

Thalidomidesmall_molecule

unknown

Curated

← investigated for

Tanespimycinsmall_molecule

unknown

Curated

← investigated for

Talazoparibsmall_molecule

unknown

Curated

← investigated for

Sorafenib Tosylatesmall_molecule

unknown

Curated

← investigated for

Sorafenibsmall_molecule

unknown

Curated

← investigated for

Retaspimycin Hydrochloridesmall_molecule

unknown

Curated

← investigated for

Pertuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Perifosinesmall_molecule

unknown

Curated

← investigated for

Pegfilgrastimother

unknown

Curated

← investigated for

Pazopanibsmall_molecule

unknown

Curated

← investigated for

Paclitaxelsmall_molecule

unknown

Curated

← investigated for

Nivolumabmonoclonal_antibody

unknown

Curated

← investigated for

Niraparibsmall_molecule

unknown

Curated

← investigated for

Nintedanibsmall_molecule

unknown

Curated

← investigated for

Neratinibsmall_molecule

unknown

Curated

← investigated for

Metforminsmall_molecule

unknown

Curated

← investigated for

Linsitinibsmall_molecule

unknown

Curated

← investigated for

Lenalidomidesmall_molecule

unknown

Curated

← investigated for

Ipilimumabmonoclonal_antibody

unknown

Curated

← investigated for

Interferon Alfa-2bother

unknown

Curated

← investigated for

Ganetespibsmall_molecule

unknown

Curated

← investigated for

Fulvestrantsmall_molecule

unknown

Curated

← investigated for

Filgrastimother

unknown

Curated

← investigated for

Etoposidesmall_molecule

unknown

Curated

← investigated for

Eribulinsmall_molecule

unknown

Curated

← investigated for

Erdafitinibsmall_molecule

unknown

Curated

← investigated for

Durvalumabmonoclonal_antibody

unknown

Curated

← investigated for

Doxorubicinsmall_molecule

unknown

Curated

← investigated for

Cyclophosphamidesmall_molecule

unknown

Curated

← investigated for

Cixutumumabmonoclonal_antibody

unknown

Curated

← investigated for

Cisplatinsmall_molecule

unknown

Curated

← investigated for

Cinacalcetsmall_molecule

unknown

Curated

← investigated for

Cetuximabmonoclonal_antibody

unknown

Curated

← investigated for

Celecoxibsmall_molecule

unknown

Curated

← investigated for

Cediranibsmall_molecule

unknown

Curated

← investigated for

Carboplatinsmall_molecule

unknown

Curated

← investigated for

Capivasertibsmall_molecule

unknown

Curated

← investigated for

Cabozantinibsmall_molecule

unknown

Curated

← investigated for

Bortezomibsmall_molecule

unknown

Curated

← investigated for

Berzosertibsmall_molecule

unknown

Curated

← investigated for

Azacitidinesmall_molecule

unknown

Curated

← investigated for

Axitinibsmall_molecule

unknown

Curated

← investigated for

Aspirinsmall_molecule

unknown

Curated

← investigated for

Alisertibsmall_molecule

unknown

Curated

← investigated for

Afatinibsmall_molecule

unknown

Curated

← investigated for

Vismodegibsmall_molecule

unknown

Curated

← investigated for

Venetoclaxsmall_molecule

unknown

Curated

← investigated for

Temsirolimussmall_molecule

unknown

Curated

← investigated for

Temozolomidesmall_molecule

unknown

Curated

← investigated for

Tazemetostatsmall_molecule

unknown

Curated

← investigated for

Sirolimussmall_molecule

unknown

Curated

← investigated for

Ribociclibsmall_molecule

unknown

Curated

← investigated for

Pexidartinibsmall_molecule

unknown

Curated

← investigated for

Pasireotideother

unknown

Curated

← investigated for

Panobinostatsmall_molecule

unknown

Curated

← investigated for

Imiquimodsmall_molecule

unknown

Curated

← investigated for

Imatinib Mesylatesmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

unknown

Curated

← investigated for

Gefitinibsmall_molecule

unknown

Curated

← investigated for

Fludarabinesmall_molecule

unknown

Curated

← investigated for

Decitabinesmall_molecule

unknown

Curated

← investigated for

Daratumumabmonoclonal_antibody

unknown

Curated

← investigated for

Bendamustinesmall_molecule

unknown

Curated

← investigated for

Avelumabmonoclonal_antibody

unknown

Curated

← investigated for

Abemaciclibsmall_molecule

unknown

Curated

← investigated for

Hydroxychloroquinesmall_molecule

unknown

0.5

Curated

Prostate Neoplasm altered in cohorts of …ALTERED_INderived15 of 144show all (up to 200)
← altered in cohorts of	CCAR2 298 / 500 cases (60 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	BIN3 297 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	C8orf58 297 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	XPO7 297 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	BMP1 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	PEBP4 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	PIWIL2 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	PPP3CC 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	RHOBTB2 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	SORBS3 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	TNFRSF10C 296 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	DMTN 295 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	DOK2 295 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	EGR3 295 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	FAM160B2 295 / 500 cases (59 %) · ssm · TCGA-PRAD	—	—	Prostate Adenocarcinoma	1	Observed	gdc	graph →

Prostate Neoplasm altered in cohorts of …ALTERED_INderived15 of 144show all (up to 200)

← altered in cohorts of

CCAR2

298 / 500 cases (60 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

BIN3

297 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

C8orf58

297 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

XPO7

297 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

BMP1

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

PEBP4

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

PIWIL2

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

PPP3CC

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

RHOBTB2

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

SORBS3

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

TNFRSF10C

296 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

DMTN

295 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

DOK2

295 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

EGR3

295 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

← altered in cohorts of

FAM160B2

295 / 500 cases (59 %) · ssm · TCGA-PRAD

—

Observed

Prostate Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 241show all (up to 200)
→ investigated in trials for	Docetaxelsmall_molecule 267 trials (47 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	267	Observed	clinicaltrials	graph →
→ investigated in trials for	Enzalutamidesmall_molecule 225 trials (80 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	225	Observed	clinicaltrials	graph →
→ investigated in trials for	Prednisonesmall_molecule 225 trials (51 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	225	Observed	clinicaltrials	graph →
→ investigated in trials for	Leuprolideother 138 trials (30 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	138	Observed	clinicaltrials	graph →
→ investigated in trials for	Abiraterone Acetatesmall_molecule 136 trials (45 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	136	Observed	clinicaltrials	graph →
→ investigated in trials for	Bicalutamidesmall_molecule 114 trials (18 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	114	Observed	clinicaltrials	graph →
→ investigated in trials for	Goserelinother 96 trials (17 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	96	Observed	clinicaltrials	graph →
→ investigated in trials for	Degarelixother 92 trials (20 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	92	Observed	clinicaltrials	graph →
→ investigated in trials for	Apalutamidesmall_molecule 91 trials (44 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	91	Observed	clinicaltrials	graph →
→ investigated in trials for	Abirateronesmall_molecule 90 trials (37 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	90	Observed	clinicaltrials	graph →
→ investigated in trials for	Darolutamidesmall_molecule 62 trials (41 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	62	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabazitaxelsmall_molecule 52 trials (16 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	52	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal_antibody 50 trials (18 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	50	Observed	clinicaltrials	graph →
→ investigated in trials for	Flutamidesmall_molecule 45 trials (5 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	45	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall_molecule 44 trials (17 active) · roll-up of the cancer and its descendants	—	—	Prostate Neoplasm	44	Observed	clinicaltrials	graph →

Prostate Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 241show all (up to 200)

→ investigated in trials for

Docetaxelsmall_molecule

267 trials (47 active) · roll-up of the cancer and its descendants

—

267

Observed

→ investigated in trials for

Enzalutamidesmall_molecule

225 trials (80 active) · roll-up of the cancer and its descendants

—

225

Observed

→ investigated in trials for

Prednisonesmall_molecule

225 trials (51 active) · roll-up of the cancer and its descendants

—

225

Observed

→ investigated in trials for

Leuprolideother

138 trials (30 active) · roll-up of the cancer and its descendants

—

138

Observed

→ investigated in trials for

Abiraterone Acetatesmall_molecule

136 trials (45 active) · roll-up of the cancer and its descendants

—

136

Observed

→ investigated in trials for

Bicalutamidesmall_molecule

114 trials (18 active) · roll-up of the cancer and its descendants

—

114

Observed

→ investigated in trials for

Goserelinother

96 trials (17 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Degarelixother

92 trials (20 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Apalutamidesmall_molecule

91 trials (44 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Abirateronesmall_molecule

90 trials (37 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Darolutamidesmall_molecule

62 trials (41 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cabazitaxelsmall_molecule

52 trials (16 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal_antibody

50 trials (18 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Flutamidesmall_molecule

45 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Carboplatinsmall_molecule

44 trials (17 active) · roll-up of the cancer and its descendants

—

Observed

Prostate Neoplasm studied in …STUDIED_INderived10 of 6,544show all (up to 200)
→ studied in	NCT01230866Phase 3 · active not recruiting Study of Hypo-fractionated Proton Radiation for Low Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01492972Phase 3 · recruiting Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)	—	—	Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03866382Phase 2 · recruiting Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · condition mapped CURATED_BROADER · 6,544 trials mapped (1,848 active)	—	—	Prostate Small Cell Neuroendocrine Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04736199Phase 3 · completed Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer · condition mapped ALIAS · 6,544 trials mapped (1,848 active)	—	—	Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05081193Phase 2 · active not recruiting Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05148156NA · recruiting Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer. · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)	—	—	Benign Prostatic Hyperplasia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06011304Phase 3 · completed Study of 18F-Florastamin PET/CT Imaging in Patients With at Least Intermediate Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06541210NA · recruiting Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)	—	—	Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06738303Phase 2 · recruiting Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer · condition mapped CURATED_BROADER · 6,544 trials mapped (1,848 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →

Prostate Neoplasm studied in …STUDIED_INderived10 of 6,544show all (up to 200)

→ studied in

NCT01230866Phase 3 · active not recruiting

Study of Hypo-fractionated Proton Radiation for Low Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT01492972Phase 3 · recruiting

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT02465060Phase 2 · active not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)

—

Prostate Carcinoma

Observed

Prostate Small Cell Neuroendocrine Carcinoma

→ studied in

NCT03866382Phase 2 · recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · condition mapped CURATED_BROADER · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT04736199Phase 3 · completed

Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer · condition mapped ALIAS · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT05081193Phase 2 · active not recruiting

Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)

—

Observed

Benign Prostatic Hyperplasia

→ studied in

NCT05148156NA · recruiting

Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer. · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT06011304Phase 3 · completed

Study of 18F-Florastamin PET/CT Imaging in Patients With at Least Intermediate Risk Prostate Cancer · condition mapped CURATED_EXACT · 6,544 trials mapped (1,848 active)

—

Observed

→ studied in

NCT06541210NA · recruiting

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men · condition mapped ONTOLOGY_EXACT · 6,544 trials mapped (1,848 active)

—

Prostate Carcinoma

Observed

→ studied in

NCT06738303Phase 2 · recruiting

Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer · condition mapped CURATED_BROADER · 6,544 trials mapped (1,848 active)

—

Observed