Myeloproliferative Neoplasm

Curated

in context · predicts response to

FGFR1 Fusionfusion → predicts response to Midostaurin

sensitivity

Curated

Myeloproliferative Neoplasm associated with …ASSOCIATED_WITH2 of 2
← associated with	PDGFRB	supports	A	Myeloproliferative Neoplasm	1	Curated	civic	graph →
← associated with	FGFR1	supports	C	Myeloproliferative Neoplasm	1	Curated	civic	graph →

Myeloproliferative Neoplasm associated with …ASSOCIATED_WITH2 of 2

← associated with

PDGFRB

supports

Curated

← associated with

FGFR1

supports

Curated

Myeloproliferative Neoplasm investigated for …INVESTIGATED_FOR51 of 51show fewer
← investigated for	Imatinibsmall_molecule	supports	A	Myeloproliferative Neoplasm	1	Curated	civic	graph →
← investigated for	Ruxolitinibsmall_molecule	unknown	4	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Momelotinibsmall_molecule	unknown	4	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Fedratinibsmall_molecule	unknown	4	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Anagrelidesmall_molecule	unknown	4	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Midostaurinsmall_molecule	supports	C	Myeloproliferative Neoplasm	1	Curated	civic	graph →
← investigated for	Tretinoinsmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Thioguaninesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Mitoxantronesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Methotrexatesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Idarubicinsmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Hydroxyureasmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Hydroxycarbamidesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Filgrastimother	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Etoposidesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Decitabinesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Daunorubicinsmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Cytarabinesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Cyclophosphamidesmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Asparaginaseother	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Amphotericin Bsmall_molecule	unknown	3	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Venetoclaxsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Thiotepasmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Tanespimycinsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Prednisonesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Pomalidomidesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Pemigatinibsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Pacritinibsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Melphalansmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Luminespibsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Lenalidomidesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Imatinib Mesylatesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Guadecitabinesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Fludarabinesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Carboplatinsmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Busulfansmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Azacitidinesmall_molecule	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Alemtuzumabmonoclonal_antibody	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Aldesleukinother	unknown	2	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Topotecansmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Tipifarnibsmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Nelarabinesmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Navtemadlinsmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Leucovorinsmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Ifosfamidesmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Fluorouracilsmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Docetaxelsmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Cladribinesmall_molecule	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Bevacizumabmonoclonal_antibody	unknown	1	Myeloproliferative Neoplasm	1	Curated	chembl	graph →
← investigated for	Bortezomibsmall_molecule	unknown	0.5	Myeloproliferative Neoplasm	1	Curated	chembl	graph →

Myeloproliferative Neoplasm investigated for …INVESTIGATED_FOR51 of 51show fewer

← investigated for

Imatinibsmall_molecule

supports

Curated

← investigated for

Ruxolitinibsmall_molecule

unknown

Curated

← investigated for

Momelotinibsmall_molecule

unknown

Curated

← investigated for

Fedratinibsmall_molecule

unknown

Curated

← investigated for

Anagrelidesmall_molecule

unknown

Curated

← investigated for

Midostaurinsmall_molecule

supports

Curated

← investigated for

Tretinoinsmall_molecule

unknown

Curated

← investigated for

Thioguaninesmall_molecule

unknown

Curated

← investigated for

Mitoxantronesmall_molecule

unknown

Curated

← investigated for

Methotrexatesmall_molecule

unknown

Curated

← investigated for

Idarubicinsmall_molecule

unknown

Curated

← investigated for

Hydroxyureasmall_molecule

unknown

Curated

← investigated for

Hydroxycarbamidesmall_molecule

unknown

Curated

← investigated for

Filgrastimother

unknown

Curated

← investigated for

Etoposidesmall_molecule

unknown

Curated

← investigated for

Decitabinesmall_molecule

unknown

Curated

← investigated for

Daunorubicinsmall_molecule

unknown

Curated

← investigated for

Cytarabinesmall_molecule

unknown

Curated

← investigated for

Cyclophosphamidesmall_molecule

unknown

Curated

← investigated for

Asparaginaseother

unknown

Curated

← investigated for

Amphotericin Bsmall_molecule

unknown

Curated

← investigated for

Venetoclaxsmall_molecule

unknown

Curated

← investigated for

Thiotepasmall_molecule

unknown

Curated

← investigated for

Tanespimycinsmall_molecule

unknown

Curated

← investigated for

Prednisonesmall_molecule

unknown

Curated

← investigated for

Pomalidomidesmall_molecule

unknown

Curated

← investigated for

Pemigatinibsmall_molecule

unknown

Curated

← investigated for

Pacritinibsmall_molecule

unknown

Curated

← investigated for

Melphalansmall_molecule

unknown

Curated

← investigated for

Luminespibsmall_molecule

unknown

Curated

← investigated for

Lenalidomidesmall_molecule

unknown

Curated

← investigated for

Imatinib Mesylatesmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

unknown

Curated

← investigated for

Guadecitabinesmall_molecule

unknown

Curated

← investigated for

Fludarabinesmall_molecule

unknown

Curated

← investigated for

Carboplatinsmall_molecule

unknown

Curated

← investigated for

Busulfansmall_molecule

unknown

Curated

← investigated for

Azacitidinesmall_molecule

unknown

Curated

← investigated for

Alemtuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Aldesleukinother

unknown

Curated

← investigated for

Topotecansmall_molecule

unknown

Curated

← investigated for

Tipifarnibsmall_molecule

unknown

Curated

← investigated for

Nelarabinesmall_molecule

unknown

Curated

← investigated for

Navtemadlinsmall_molecule

unknown

Curated

← investigated for

Leucovorinsmall_molecule

unknown

Curated

← investigated for

Ifosfamidesmall_molecule

unknown

Curated

← investigated for

Fluorouracilsmall_molecule

unknown

Curated

← investigated for

Docetaxelsmall_molecule

unknown

Curated

← investigated for

Cladribinesmall_molecule

unknown

Curated

← investigated for

Bevacizumabmonoclonal_antibody

unknown

Curated

← investigated for

Bortezomibsmall_molecule

unknown

0.5

Curated

Myeloproliferative Neoplasm altered in cohorts of …ALTERED_INderived15 of 119show all (up to 200)
← altered in cohorts of	JAK2 112 / 151 cases (74 %) · ssm · mpn_cimr_2013	—	—	Myeloproliferative Neoplasm	1	Observed	cbioportal	graph →
← altered in cohorts of	FLT3 278 / 903 cases (31 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts	—	—	Acute Myeloid Leukemia	7	Observed	cbioportal	graph →
← altered in cohorts of	NPM1 233 / 903 cases (26 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts	—	—	Acute Myeloid Leukemia	7	Observed	cbioportal	graph →
← altered in cohorts of	DNMT3A 197 / 903 cases (22 %) · ssm · aml_ohsu_2022 · largest of 5 cohorts	—	—	Acute Myeloid Leukemia	5	Observed	cbioportal	graph →
← altered in cohorts of	CALR 25 / 151 cases (17 %) · ssm · mpn_cimr_2013	—	—	Myeloproliferative Neoplasm	1	Observed	cbioportal	graph →
← altered in cohorts of	VIPR2 29 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	C8orf33 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	COMMD5 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	DLGAP2 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	MYC 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	RPL8 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	ZNF16 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	ZNF250 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	ZNF517 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →
← altered in cohorts of	ZNF7 27 / 200 cases (14 %) · ssm · TCGA-LAML	—	—	Acute Myeloid Leukemia	1	Observed	gdc	graph →

Myeloproliferative Neoplasm altered in cohorts of …ALTERED_INderived15 of 119show all (up to 200)

← altered in cohorts of

JAK2

112 / 151 cases (74 %) · ssm · mpn_cimr_2013

—

Observed

← altered in cohorts of

FLT3

278 / 903 cases (31 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts

—

Observed

← altered in cohorts of

NPM1

233 / 903 cases (26 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts

—

Observed

← altered in cohorts of

DNMT3A

197 / 903 cases (22 %) · ssm · aml_ohsu_2022 · largest of 5 cohorts

—

Observed

← altered in cohorts of

CALR

25 / 151 cases (17 %) · ssm · mpn_cimr_2013

—

Observed

← altered in cohorts of

VIPR2

29 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

C8orf33

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

COMMD5

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

DLGAP2

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

MYC

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

RPL8

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

ZNF16

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

ZNF250

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

ZNF517

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

← altered in cohorts of

ZNF7

27 / 200 cases (14 %) · ssm · TCGA-LAML

—

Observed

Myeloproliferative Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 232show all (up to 200)
→ investigated in trials for	Cytarabinesmall_molecule 408 trials (100 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	408	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall_molecule 330 trials (92 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	330	Observed	clinicaltrials	graph →
→ investigated in trials for	Azacitidinesmall_molecule 309 trials (143 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	309	Observed	clinicaltrials	graph →
→ investigated in trials for	Venetoclaxsmall_molecule 278 trials (177 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	278	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall_molecule 225 trials (62 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	225	Observed	clinicaltrials	graph →
→ investigated in trials for	Decitabinesmall_molecule 154 trials (40 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	154	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall_molecule 137 trials (34 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	137	Observed	clinicaltrials	graph →
→ investigated in trials for	Idarubicinsmall_molecule 108 trials (31 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	108	Observed	clinicaltrials	graph →
→ investigated in trials for	Daunorubicinsmall_molecule 96 trials (34 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	96	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall_molecule 87 trials (20 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	87	Observed	clinicaltrials	graph →
→ investigated in trials for	Ruxolitinibsmall_molecule 85 trials (37 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	85	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall_molecule 83 trials (11 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	83	Observed	clinicaltrials	graph →
→ investigated in trials for	Dasatinibsmall molecule 79 trials (12 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	79	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall_molecule 78 trials (28 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	78	Observed	clinicaltrials	graph →
→ investigated in trials for	Nilotinibsmall molecule 73 trials (9 active) · roll-up of the cancer and its descendants	—	—	Myeloproliferative Neoplasm	73	Observed	clinicaltrials	graph →

Myeloproliferative Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 232show all (up to 200)

→ investigated in trials for

Cytarabinesmall_molecule

408 trials (100 active) · roll-up of the cancer and its descendants

—

408

Observed

→ investigated in trials for

Fludarabinesmall_molecule

330 trials (92 active) · roll-up of the cancer and its descendants

—

330

Observed

→ investigated in trials for

Azacitidinesmall_molecule

309 trials (143 active) · roll-up of the cancer and its descendants

—

309

Observed

→ investigated in trials for

Venetoclaxsmall_molecule

278 trials (177 active) · roll-up of the cancer and its descendants

—

278

Observed

→ investigated in trials for

Cyclophosphamidesmall_molecule

225 trials (62 active) · roll-up of the cancer and its descendants

—

225

Observed

→ investigated in trials for

Decitabinesmall_molecule

154 trials (40 active) · roll-up of the cancer and its descendants

—

154

Observed

→ investigated in trials for

Busulfansmall_molecule

137 trials (34 active) · roll-up of the cancer and its descendants

—

137

Observed

→ investigated in trials for

Idarubicinsmall_molecule

108 trials (31 active) · roll-up of the cancer and its descendants

—

108

Observed

→ investigated in trials for

Daunorubicinsmall_molecule

96 trials (34 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Methotrexatesmall_molecule

87 trials (20 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ruxolitinibsmall_molecule

85 trials (37 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Etoposidesmall_molecule

83 trials (11 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dasatinibsmall molecule

79 trials (12 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Melphalansmall_molecule

78 trials (28 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nilotinibsmall molecule

73 trials (9 active) · roll-up of the cancer and its descendants

—

Observed

Myeloproliferative Neoplasm studied in …STUDIED_INderived10 of 4,033show all (up to 200)
→ studied in	NCT03494569Phase 1 · suspended Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03560752Phase 1 · active not recruiting CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant · condition mapped ALIAS · 4,033 trials mapped (1,139 active)	—	—	Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT04429191Phase 1 · completed JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT05015426Phase 1 · active not recruiting Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT05025488Phase 1 · active not recruiting Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Myeloproliferative Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05554393Phase 2 · recruiting Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial) · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06484062Phase 1 · recruiting Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06651229Phase 1 · active not recruiting A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms · condition mapped ALIAS · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06904066Phase 1 · recruiting Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07437950Phase 2 · recruiting Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →

Myeloproliferative Neoplasm studied in …STUDIED_INderived10 of 4,033show all (up to 200)

→ studied in

NCT03494569Phase 1 · suspended

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

—

Observed

Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ studied in

NCT03560752Phase 1 · active not recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant · condition mapped ALIAS · 4,033 trials mapped (1,139 active)

—

Observed

→ studied in

NCT04429191Phase 1 · completed

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

—

Observed

→ studied in

NCT05015426Phase 1 · active not recruiting

Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

—

Observed

→ studied in

NCT05025488Phase 1 · active not recruiting

Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

—

Observed

→ studied in

NCT05554393Phase 2 · recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial) · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

—

Observed

→ studied in

NCT06484062Phase 1 · recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

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Observed

→ studied in

NCT06651229Phase 1 · active not recruiting

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms · condition mapped ALIAS · 4,033 trials mapped (1,139 active)

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Observed

→ studied in

NCT06904066Phase 1 · recruiting

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

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Observed

→ studied in

NCT07437950Phase 2 · recruiting

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) · condition mapped CURATED_BROADER · 4,033 trials mapped (1,139 active)

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Observed