Hematopoietic and Lymphoid Cell Neoplasm

Curated

Hematopoietic and Lymphoid Cell Neoplasm diagnostic of …DIAGNOSTIC_OF3 of 3
← diagnostic of	JAK2 Fusionfusion	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← diagnostic of	FGFR1 Fusionfusion	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← diagnostic of	PDGFRB Fusionfusion	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →

Hematopoietic and Lymphoid Cell Neoplasm diagnostic of …DIAGNOSTIC_OF3 of 3

← diagnostic of

JAK2 Fusionfusion

supports

Curated

← diagnostic of

FGFR1 Fusionfusion

supports

Curated

← diagnostic of

PDGFRB Fusionfusion

supports

Curated

Hematopoietic and Lymphoid Cell Neoplasm predisposes to …PREDISPOSES_TO1 of 1
← predisposes to	DDX41 R164WSNV	supports	C	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →

Hematopoietic and Lymphoid Cell Neoplasm predisposes to …PREDISPOSES_TO1 of 1

← predisposes to

DDX41 R164WSNV

supports

Curated

Hematopoietic and Lymphoid Cell Neoplasm associated with …ASSOCIATED_WITH5 of 5
← associated with	JAK2	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← associated with	FGFR1	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← associated with	PDGFRB	supports	A	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← associated with	DDX41	supports	C	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← associated with	ATM	supports	D	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →

Hematopoietic and Lymphoid Cell Neoplasm associated with …ASSOCIATED_WITH5 of 5

← associated with

JAK2

supports

Curated

← associated with

FGFR1

supports

Curated

← associated with

PDGFRB

supports

Curated

← associated with

DDX41

supports

Curated

← associated with

ATM

supports

Curated

Hematopoietic and Lymphoid Cell Neoplasm investigated for …INVESTIGATED_FOR70 of 70show fewer
← investigated for	Ibandronic Acidsmall_molecule	unknown	3	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Cyclophosphamidesmall_molecule	unknown	3	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Olaparibsmall_molecule	supports	D	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	civic	graph →
← investigated for	Vincristinesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Venetoclaxsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Vemurafenibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Treosulfansmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Trastuzumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Thiotepasmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Ruxolitinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Rituximabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Prednisonesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Plerixaforsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Pertuzumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Pembrolizumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Peginterferon Alfa-2bother	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Pegfilgrastimother	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Pasireotideother	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Panobinostatsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Nivolumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Methotrexatesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Melphalansmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Lenalidomidesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Ixazomibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Inotuzumab Ozogamicinadc	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Ibrutinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Fludarabinesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Filgrastimother	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Etoposidesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Erlotinib Hydrochloridesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Erlotinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Entrectinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Elotuzumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Duvelisibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Doxorubicinsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Dexamethasonesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Cytarabinesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Crisantaspaseother	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Cobimetinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Busulfansmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Brexucabtagene Autoleucelgene_therapy	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Bortezomibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Blinatumomabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Bendamustinesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Azacitidinesmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Axicabtagene Ciloleucelgene_therapy	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Atezolizumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Alemtuzumabmonoclonal_antibody	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Alectinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Acalabrutinibsmall_molecule	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Tretinoinsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Tafasitamabmonoclonal_antibody	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Sirolimussmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Selinexorsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Romidepsinother	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	RG7112small_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Oxaliplatinsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Mosunetuzumabmonoclonal_antibody	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Isatuximabmonoclonal_antibody	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Interferon Alfa-2bother	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Imatinib Mesylatesmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Enasidenibsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Decitabinesmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Daunorubicinsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Capivasertibsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Brentuximab Vedotinadc	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Belinostatsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Alvocidibsmall_molecule	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
← investigated for	Aldesleukinother	unknown	1	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →

Hematopoietic and Lymphoid Cell Neoplasm investigated for …INVESTIGATED_FOR70 of 70show fewer

← investigated for

Ibandronic Acidsmall_molecule

unknown

Curated

← investigated for

Cyclophosphamidesmall_molecule

unknown

Curated

← investigated for

Olaparibsmall_molecule

supports

Curated

← investigated for

Vincristinesmall_molecule

unknown

Curated

← investigated for

Venetoclaxsmall_molecule

unknown

Curated

← investigated for

Vemurafenibsmall_molecule

unknown

Curated

← investigated for

Treosulfansmall_molecule

unknown

Curated

← investigated for

Trastuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Thiotepasmall_molecule

unknown

Curated

← investigated for

Ruxolitinibsmall_molecule

unknown

Curated

← investigated for

Rituximabmonoclonal_antibody

unknown

Curated

← investigated for

Prednisonesmall_molecule

unknown

Curated

← investigated for

Plerixaforsmall_molecule

unknown

Curated

← investigated for

Pertuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Pembrolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Peginterferon Alfa-2bother

unknown

Curated

← investigated for

Pegfilgrastimother

unknown

Curated

← investigated for

Pasireotideother

unknown

Curated

← investigated for

Panobinostatsmall_molecule

unknown

Curated

← investigated for

Nivolumabmonoclonal_antibody

unknown

Curated

← investigated for

Methotrexatesmall_molecule

unknown

Curated

← investigated for

Melphalansmall_molecule

unknown

Curated

← investigated for

Lenalidomidesmall_molecule

unknown

Curated

← investigated for

Ixazomibsmall_molecule

unknown

Curated

← investigated for

Inotuzumab Ozogamicinadc

unknown

Curated

← investigated for

Ibrutinibsmall_molecule

unknown

Curated

← investigated for

Fludarabinesmall_molecule

unknown

Curated

← investigated for

Filgrastimother

unknown

Curated

← investigated for

Etoposidesmall_molecule

unknown

Curated

← investigated for

Erlotinib Hydrochloridesmall_molecule

unknown

Curated

← investigated for

Erlotinibsmall_molecule

unknown

Curated

← investigated for

Entrectinibsmall_molecule

unknown

Curated

← investigated for

Elotuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Duvelisibsmall_molecule

unknown

Curated

← investigated for

Doxorubicinsmall_molecule

unknown

Curated

← investigated for

Dexamethasonesmall_molecule

unknown

Curated

← investigated for

Cytarabinesmall_molecule

unknown

Curated

← investigated for

Crisantaspaseother

unknown

Curated

← investigated for

Cobimetinibsmall_molecule

unknown

Curated

← investigated for

Busulfansmall_molecule

unknown

Curated

← investigated for

Brexucabtagene Autoleucelgene_therapy

unknown

Curated

← investigated for

Bortezomibsmall_molecule

unknown

Curated

← investigated for

Blinatumomabmonoclonal_antibody

unknown

Curated

← investigated for

Bendamustinesmall_molecule

unknown

Curated

← investigated for

Azacitidinesmall_molecule

unknown

Curated

← investigated for

Axicabtagene Ciloleucelgene_therapy

unknown

Curated

← investigated for

Atezolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Alemtuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Alectinibsmall_molecule

unknown

Curated

← investigated for

Acalabrutinibsmall_molecule

unknown

Curated

← investigated for

Tretinoinsmall_molecule

unknown

Curated

← investigated for

Tafasitamabmonoclonal_antibody

unknown

Curated

← investigated for

Sirolimussmall_molecule

unknown

Curated

← investigated for

Selinexorsmall_molecule

unknown

Curated

← investigated for

Romidepsinother

unknown

Curated

← investigated for

RG7112small_molecule

unknown

Curated

← investigated for

Oxaliplatinsmall_molecule

unknown

Curated

← investigated for

Mosunetuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Isatuximabmonoclonal_antibody

unknown

Curated

← investigated for

Interferon Alfa-2bother

unknown

Curated

← investigated for

Imatinib Mesylatesmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

unknown

Curated

← investigated for

Enasidenibsmall_molecule

unknown

Curated

← investigated for

Decitabinesmall_molecule

unknown

Curated

← investigated for

Daunorubicinsmall_molecule

unknown

Curated

← investigated for

Capivasertibsmall_molecule

unknown

Curated

← investigated for

Brentuximab Vedotinadc

unknown

Curated

← investigated for

Belinostatsmall_molecule

unknown

Curated

← investigated for

Alvocidibsmall_molecule

unknown

Curated

← investigated for

Aldesleukinother

unknown

Curated

Hematopoietic and Lymphoid Cell Neoplasm altered in cohorts of …ALTERED_INderived15 of 397show all (up to 200)
← altered in cohorts of	IGHV2-70 437 / 961 cases (45 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts	—	—	Multiple Myeloma	2	Observed	gdc	graph →
← altered in cohorts of	DDX3X 124 / 297 cases (42 %) · ssm · mbn_sfu_2023	—	—	B-Cell Non-Hodgkin Lymphoma	1	Observed	cbioportal	graph →
← altered in cohorts of	IGLV3-1 364 / 961 cases (38 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts	—	—	Multiple Myeloma	2	Observed	gdc	graph →
← altered in cohorts of	FLT3 278 / 903 cases (31 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts	—	—	Acute Myeloid Leukemia	7	Observed	cbioportal	graph →
← altered in cohorts of	SHCBP1 73 / 263 cases (28 %) · ssm · CGCI-BLGSP	—	—	Burkitt Lymphoma	1	Observed	gdc	graph →
← altered in cohorts of	NPM1 233 / 903 cases (26 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts	—	—	Acute Myeloid Leukemia	7	Observed	cbioportal	graph →
← altered in cohorts of	VPS35 67 / 263 cases (25 %) · ssm · CGCI-BLGSP	—	—	Burkitt Lymphoma	1	Observed	gdc	graph →
← altered in cohorts of	ORC6 66 / 263 cases (25 %) · ssm · CGCI-BLGSP	—	—	Burkitt Lymphoma	1	Observed	gdc	graph →
← altered in cohorts of	TPTE 66 / 263 cases (25 %) · ssm · CGCI-BLGSP	—	—	Burkitt Lymphoma	1	Observed	gdc	graph →
← altered in cohorts of	IGHV2-70D 238 / 961 cases (25 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts	—	—	Multiple Myeloma	2	Observed	gdc	graph →
← altered in cohorts of	KMT2D 247 / 1,001 cases (25 %) · ssm · dlbcl_duke_2017 · largest of 5 cohorts	—	—	Diffuse Large B-Cell Lymphoma Unclassifiable	5	Observed	cbioportal	graph →
← altered in cohorts of	KRAS 227 / 961 cases (24 %) · ssm · MMRF-COMMPASS · largest of 4 cohorts	—	—	Multiple Myeloma	4	Observed	gdc	graph →
← altered in cohorts of	MYLK3 62 / 263 cases (24 %) · ssm · CGCI-BLGSP	—	—	Burkitt Lymphoma	1	Observed	gdc	graph →
← altered in cohorts of	CNTNAP3B 70 / 297 cases (24 %) · ssm · mbn_sfu_2023	—	—	B-Cell Non-Hodgkin Lymphoma	1	Observed	cbioportal	graph →
← altered in cohorts of	BCL7A 212 / 961 cases (22 %) · ssm · MMRF-COMMPASS · largest of 3 cohorts	—	—	Multiple Myeloma	3	Observed	gdc	graph →

Hematopoietic and Lymphoid Cell Neoplasm altered in cohorts of …ALTERED_INderived15 of 397show all (up to 200)

← altered in cohorts of

IGHV2-70

437 / 961 cases (45 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts

—

Observed

B-Cell Non-Hodgkin Lymphoma

← altered in cohorts of

DDX3X

124 / 297 cases (42 %) · ssm · mbn_sfu_2023

—

Observed

← altered in cohorts of

IGLV3-1

364 / 961 cases (38 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts

—

Observed

← altered in cohorts of

FLT3

278 / 903 cases (31 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts

—

Observed

← altered in cohorts of

SHCBP1

73 / 263 cases (28 %) · ssm · CGCI-BLGSP

—

Observed

← altered in cohorts of

NPM1

233 / 903 cases (26 %) · ssm · aml_ohsu_2022 · largest of 7 cohorts

—

Observed

← altered in cohorts of

VPS35

67 / 263 cases (25 %) · ssm · CGCI-BLGSP

—

Observed

← altered in cohorts of

ORC6

66 / 263 cases (25 %) · ssm · CGCI-BLGSP

—

Observed

← altered in cohorts of

TPTE

66 / 263 cases (25 %) · ssm · CGCI-BLGSP

—

Observed

← altered in cohorts of

IGHV2-70D

238 / 961 cases (25 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts

—

Observed

Diffuse Large B-Cell Lymphoma Unclassifiable

← altered in cohorts of

KMT2D

247 / 1,001 cases (25 %) · ssm · dlbcl_duke_2017 · largest of 5 cohorts

—

Observed

← altered in cohorts of

KRAS

227 / 961 cases (24 %) · ssm · MMRF-COMMPASS · largest of 4 cohorts

—

Observed

← altered in cohorts of

MYLK3

62 / 263 cases (24 %) · ssm · CGCI-BLGSP

—

Observed

B-Cell Non-Hodgkin Lymphoma

← altered in cohorts of

CNTNAP3B

70 / 297 cases (24 %) · ssm · mbn_sfu_2023

—

Observed

← altered in cohorts of

BCL7A

212 / 961 cases (22 %) · ssm · MMRF-COMMPASS · largest of 3 cohorts

—

Observed

Hematopoietic and Lymphoid Cell Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 349show all (up to 200)
→ investigated in trials for	Cyclophosphamidesmall_molecule 891 trials (224 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	891	Observed	clinicaltrials	graph →
→ investigated in trials for	Dexamethasonesmall_molecule 878 trials (266 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	878	Observed	clinicaltrials	graph →
→ investigated in trials for	Cytarabinesmall_molecule 711 trials (138 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	711	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall_molecule 699 trials (168 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	699	Observed	clinicaltrials	graph →
→ investigated in trials for	Lenalidomidesmall_molecule 510 trials (158 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	510	Observed	clinicaltrials	graph →
→ investigated in trials for	Bortezomibsmall_molecule 457 trials (102 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	457	Observed	clinicaltrials	graph →
→ investigated in trials for	Azacitidinesmall_molecule 387 trials (159 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	387	Observed	clinicaltrials	graph →
→ investigated in trials for	Venetoclaxsmall_molecule 374 trials (230 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	374	Observed	clinicaltrials	graph →
→ investigated in trials for	Rituximabmonoclonal_antibody 341 trials (82 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	341	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall_molecule 319 trials (53 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	319	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall_molecule 317 trials (55 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	317	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall_molecule 316 trials (59 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	316	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall_molecule 269 trials (46 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	269	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 253 trials (22 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	253	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall_molecule 226 trials (65 active) · roll-up of the cancer and its descendants	—	—	Hematopoietic and Lymphoid Cell Neoplasm	226	Observed	clinicaltrials	graph →

Hematopoietic and Lymphoid Cell Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 349show all (up to 200)

→ investigated in trials for

Cyclophosphamidesmall_molecule

891 trials (224 active) · roll-up of the cancer and its descendants

—

891

Observed

→ investigated in trials for

Dexamethasonesmall_molecule

878 trials (266 active) · roll-up of the cancer and its descendants

—

878

Observed

→ investigated in trials for

Cytarabinesmall_molecule

711 trials (138 active) · roll-up of the cancer and its descendants

—

711

Observed

→ investigated in trials for

Fludarabinesmall_molecule

699 trials (168 active) · roll-up of the cancer and its descendants

—

699

Observed

→ investigated in trials for

Lenalidomidesmall_molecule

510 trials (158 active) · roll-up of the cancer and its descendants

—

510

Observed

→ investigated in trials for

Bortezomibsmall_molecule

457 trials (102 active) · roll-up of the cancer and its descendants

—

457

Observed

→ investigated in trials for

Azacitidinesmall_molecule

387 trials (159 active) · roll-up of the cancer and its descendants

—

387

Observed

→ investigated in trials for

Venetoclaxsmall_molecule

374 trials (230 active) · roll-up of the cancer and its descendants

—

374

Observed

→ investigated in trials for

Rituximabmonoclonal_antibody

341 trials (82 active) · roll-up of the cancer and its descendants

—

341

Observed

→ investigated in trials for

Etoposidesmall_molecule

319 trials (53 active) · roll-up of the cancer and its descendants

—

319

Observed

→ investigated in trials for

Melphalansmall_molecule

317 trials (55 active) · roll-up of the cancer and its descendants

—

317

Observed

→ investigated in trials for

Methotrexatesmall_molecule

316 trials (59 active) · roll-up of the cancer and its descendants

—

316

Observed

→ investigated in trials for

Busulfansmall_molecule

269 trials (46 active) · roll-up of the cancer and its descendants

—

269

Observed

→ investigated in trials for

Filgrastimother

253 trials (22 active) · roll-up of the cancer and its descendants

—

253

Observed

→ investigated in trials for

Vincristinesmall_molecule

226 trials (65 active) · roll-up of the cancer and its descendants

—

226

Observed

Hematopoietic and Lymphoid Cell Neoplasm studied in …STUDIED_INderived10 of 11,157show all (up to 200)
→ studied in	NCT00421213Phase 2 · completed Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers · condition mapped ALIAS · 11,157 trials mapped (3,141 active)	—	—	Hematopoietic and Lymphoid Cell Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT00423644Phase 2 · completed A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b · condition mapped CURATED_EXACT · 11,157 trials mapped (3,141 active)	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01559935Phase 2 · completed Carfilzomib, Clarithromycin (Biaxin®), Lenalidomide (Revlimid®), and Dexamethasone (Decadron®) [Car-BiRD] Therapy for Subjects With Multiple Myeloma · condition mapped CURATED_EXACT · 11,157 trials mapped (3,141 active)	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 11,157 trials mapped (3,141 active)	—	—	Hematopoietic and Lymphoid Cell Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT03059485Phase 2 · active not recruiting DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission · condition mapped ALIAS · 11,157 trials mapped (3,141 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03187288Phase 1 · completed Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03597321Phase 2 · active not recruiting Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03679650Phase 1 · active not recruiting Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients · condition mapped ALIAS · 11,157 trials mapped (3,141 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03739814Phase 2 · recruiting Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia · condition mapped ONTOLOGY_EXACT · 11,157 trials mapped (3,141 active)	—	—	B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative	1	Observed	clinicaltrials	graph →
→ studied in	NCT03802695Phase 1 · recruiting A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →

Hematopoietic and Lymphoid Cell Neoplasm studied in …STUDIED_INderived10 of 11,157show all (up to 200)

→ studied in

NCT00421213Phase 2 · completed

Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers · condition mapped ALIAS · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT00423644Phase 2 · completed

A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b · condition mapped CURATED_EXACT · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT01559935Phase 2 · completed

Carfilzomib, Clarithromycin (Biaxin®), Lenalidomide (Revlimid®), and Dexamethasone (Decadron®) [Car-BiRD] Therapy for Subjects With Multiple Myeloma · condition mapped CURATED_EXACT · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT02465060Phase 2 · active not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT03059485Phase 2 · active not recruiting

DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission · condition mapped ALIAS · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT03187288Phase 1 · completed

Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT03597321Phase 2 · active not recruiting

Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT03679650Phase 1 · active not recruiting

Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients · condition mapped ALIAS · 11,157 trials mapped (3,141 active)

—

Observed

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

→ studied in

NCT03739814Phase 2 · recruiting

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia · condition mapped ONTOLOGY_EXACT · 11,157 trials mapped (3,141 active)

—

Observed

→ studied in

NCT03802695Phase 1 · recruiting

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies · condition mapped CURATED_BROADER · 11,157 trials mapped (3,141 active)

—

Observed