Gastrointestinal Stromal Tumor

Curated

in context · predicts response to

KIT Exon 11 Mutation → predicts response to Imatinib

sensitivity

Curated

in context · predicts response to

KIT Exon 11 Mutation → predicts response to Regorafenib Anhydrous

3 source records aggregated

sensitivity

Curated

in context · predicts response to

PDGFRA D842VSNV → predicts response to Imatinib

3 source records aggregated

resistance

Curated

in context · predicts response to

KIT Exon 9 Mutation → predicts response to Sunitinib

2 source records aggregated

sensitivity

Curated

in context · predicts response to

KIT Exon 9 Mutation → predicts response to Regorafenib Anhydrous

sensitivity

Curated

in context · predicts response to

KIT Wildtypeother → predicts response to Regorafenib Anhydrous

sensitivity

Curated

in context · predicts response to

KIT Exon 9 Mutation → predicts response to Regorafenib Anhydrous

resistance

Curated

in context · predicts response to

KIT EXPRESSIONexpression → predicts response to Imatinib

sensitivity

Curated

in context · predicts response to

KIT Exon 9 Mutation → predicts response to Imatinib

resistance

Curated

in context · predicts response to

KIT Exon 11 Mutation → predicts response to Sunitinib

resistance

Curated

in context · predicts response to

KIT Exon 9 Mutation → predicts response to Imatinib

sensitivity

Curated

in context · predicts response to

KIT V654ASNV → predicts response to Sunitinib

sensitivity

Curated

in context · predicts response to

KIT Exon 11 Mutation → predicts response to Imatinib

sensitivity

Curated

in context · predicts response to

BRAF Exon 15 Mutation → predicts response to Regorafenib Anhydrous

resistance

Curated

Gastrointestinal Stromal Tumor prognostic in …PROGNOSTIC_IN2 of 2
← prognostic in	KIT Exon 11 Mutation	supports	B	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
← prognostic in	KIT Exon 14 Mutation	supports	B	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →

Gastrointestinal Stromal Tumor prognostic in …PROGNOSTIC_IN2 of 2

← prognostic in

KIT Exon 11 Mutation

supports

Curated

← prognostic in

KIT Exon 14 Mutation

supports

Curated

Gastrointestinal Stromal Tumor diagnostic of …DIAGNOSTIC_OF1 of 1
← diagnostic of	KIT Exon 11 Mutation	supports	B	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →

Gastrointestinal Stromal Tumor diagnostic of …DIAGNOSTIC_OF1 of 1

← diagnostic of

KIT Exon 11 Mutation

supports

Curated

Gastrointestinal Stromal Tumor associated with …ASSOCIATED_WITH9 of 9
← associated with	KIT 2 source records aggregated	supports	A	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
← associated with	KIT 17 source records aggregated	supports	B	Gastrointestinal Stromal Tumor	17	Curated	civic	graph →
← associated with	PDGFRA 4 source records aggregated	supports	B	Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
← associated with	KIT 21 source records aggregated	supports	C	Gastrointestinal Stromal Tumor	21	Curated	civic	graph →
← associated with	PDGFRA 4 source records aggregated	supports	C	Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
← associated with	BRAF	supports	C	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
← associated with	NTRK3	supports	C	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
← associated with	KIT 19 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	19	Curated	civic	graph →
← associated with	PDGFRA 8 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	8	Curated	civic	graph →

Gastrointestinal Stromal Tumor associated with …ASSOCIATED_WITH9 of 9

← associated with

2 source records aggregated

supports

Curated

← associated with

17 source records aggregated

supports

Curated

← associated with

4 source records aggregated

supports

Curated

← associated with

21 source records aggregated

supports

Curated

← associated with

4 source records aggregated

supports

Curated

← associated with

BRAF

supports

Curated

← associated with

NTRK3

supports

Curated

← associated with

19 source records aggregated

supports

Curated

← associated with

8 source records aggregated

supports

Curated

Gastrointestinal Stromal Tumor investigated for …INVESTIGATED_FOR63 of 63show fewer
← investigated for	Imatinibsmall_molecule 2 source records aggregated	supports	A	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
← investigated for	Imatinibsmall_molecule 7 source records aggregated	supports	B	Gastrointestinal Stromal Tumor	7	Curated	civic	graph →
← investigated for	Regorafenib Anhydroussmall_molecule 6 source records aggregated	supports	B	Gastrointestinal Stromal Tumor	6	Curated	civic	graph →
← investigated for	Sunitinibsmall_molecule 4 source records aggregated	supports	B	Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
← investigated for	Sunitinibsmall_molecule	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Ripretinibsmall_molecule	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Imatinib Mesylatesmall_molecule	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Avapritinibsmall_molecule	unknown	4	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule 14 source records aggregated	supports	C	Gastrointestinal Stromal Tumor	14	Curated	civic	graph →
← investigated for	Sunitinibsmall_molecule 8 source records aggregated	supports	C	Gastrointestinal Stromal Tumor	8	Curated	civic	graph →
← investigated for	Regorafenib Anhydroussmall_molecule 4 source records aggregated	supports	C	Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
← investigated for	Larotrectinibsmall_molecule	supports	C	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
← investigated for	Retaspimycin Hydrochloridesmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Regorafenib Anhydroussmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Regorafenibsmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Nilotinibsmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Masitinibsmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Crenolanibsmall_molecule	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Bevacizumabmonoclonal_antibody	unknown	3	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Imatinibsmall_molecule 16 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	16	Curated	civic	graph →
← investigated for	Ponatinibsmall_molecule 9 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	9	Curated	civic	graph →
← investigated for	Sunitinibsmall_molecule 8 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	8	Curated	civic	graph →
← investigated for	Regorafenibsmall_molecule 6 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	6	Curated	civic	graph →
← investigated for	Crenolanibsmall_molecule 5 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	5	Curated	civic	graph →
← investigated for	Regorafenib Anhydroussmall_molecule 3 source records aggregated	supports	D	Gastrointestinal Stromal Tumor	3	Curated	civic	graph →
← investigated for	Pictilisibsmall_molecule	supports	D	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
← investigated for	Vandetanibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Trametinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Temozolomidesmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Sorafenib Tosylatesmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Sorafenibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Prednisonesmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Ponatinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Perifosinesmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Pembrolizumabmonoclonal_antibody	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Pazopanibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Paclitaxelsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Olaratumabmonoclonal_antibody	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Nivolumabmonoclonal_antibody	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Motesanibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Luminespibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Ipilimumabmonoclonal_antibody	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Gemcitabinesmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Ganetespibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Dovitinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Docetaxelsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Dasatinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Cisplatinsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Carboplatinsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Cabozantinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Axitinibsmall_molecule	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Atezolizumabmonoclonal_antibody	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Pexidartinibsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Oxaliplatinsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Leucovorinsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Irinotecansmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Infigratinibsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Fluorouracilsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Everolimussmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Buparlisibsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Binimetinibsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
← investigated for	Alpelisibsmall_molecule	unknown	1	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →

Gastrointestinal Stromal Tumor investigated for …INVESTIGATED_FOR63 of 63show fewer

← investigated for

Imatinibsmall_molecule

2 source records aggregated

supports

Curated

← investigated for

Imatinibsmall_molecule

7 source records aggregated

supports

Curated

← investigated for

Regorafenib Anhydroussmall_molecule

6 source records aggregated

supports

Curated

← investigated for

Sunitinibsmall_molecule

4 source records aggregated

supports

Curated

← investigated for

Sunitinibsmall_molecule

unknown

Curated

← investigated for

Ripretinibsmall_molecule

unknown

Curated

← investigated for

Imatinib Mesylatesmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

unknown

Curated

← investigated for

Avapritinibsmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

14 source records aggregated

supports

Curated

← investigated for

Sunitinibsmall_molecule

8 source records aggregated

supports

Curated

← investigated for

Regorafenib Anhydroussmall_molecule

4 source records aggregated

supports

Curated

← investigated for

Larotrectinibsmall_molecule

supports

Curated

← investigated for

Retaspimycin Hydrochloridesmall_molecule

unknown

Curated

← investigated for

Regorafenib Anhydroussmall_molecule

unknown

Curated

← investigated for

Regorafenibsmall_molecule

unknown

Curated

← investigated for

Nilotinibsmall_molecule

unknown

Curated

← investigated for

Masitinibsmall_molecule

unknown

Curated

← investigated for

Crenolanibsmall_molecule

unknown

Curated

← investigated for

Bevacizumabmonoclonal_antibody

unknown

Curated

← investigated for

Imatinibsmall_molecule

16 source records aggregated

supports

Curated

← investigated for

Ponatinibsmall_molecule

9 source records aggregated

supports

Curated

← investigated for

Sunitinibsmall_molecule

8 source records aggregated

supports

Curated

← investigated for

Regorafenibsmall_molecule

6 source records aggregated

supports

Curated

← investigated for

Crenolanibsmall_molecule

5 source records aggregated

supports

Curated

← investigated for

Regorafenib Anhydroussmall_molecule

3 source records aggregated

supports

Curated

← investigated for

Pictilisibsmall_molecule

supports

Curated

← investigated for

Vandetanibsmall_molecule

unknown

Curated

← investigated for

Trametinibsmall_molecule

unknown

Curated

← investigated for

Temozolomidesmall_molecule

unknown

Curated

← investigated for

Sorafenib Tosylatesmall_molecule

unknown

Curated

← investigated for

Sorafenibsmall_molecule

unknown

Curated

← investigated for

Prednisonesmall_molecule

unknown

Curated

← investigated for

Ponatinibsmall_molecule

unknown

Curated

← investigated for

Perifosinesmall_molecule

unknown

Curated

← investigated for

Pembrolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Pazopanibsmall_molecule

unknown

Curated

← investigated for

Paclitaxelsmall_molecule

unknown

Curated

← investigated for

Olaratumabmonoclonal_antibody

unknown

Curated

← investigated for

Nivolumabmonoclonal_antibody

unknown

Curated

← investigated for

Motesanibsmall_molecule

unknown

Curated

← investigated for

Luminespibsmall_molecule

unknown

Curated

← investigated for

Ipilimumabmonoclonal_antibody

unknown

Curated

← investigated for

Gemcitabinesmall_molecule

unknown

Curated

← investigated for

Ganetespibsmall_molecule

unknown

Curated

← investigated for

Dovitinibsmall_molecule

unknown

Curated

← investigated for

Docetaxelsmall_molecule

unknown

Curated

← investigated for

Dasatinibsmall_molecule

unknown

Curated

← investigated for

Cisplatinsmall_molecule

unknown

Curated

← investigated for

Carboplatinsmall_molecule

unknown

Curated

← investigated for

Cabozantinibsmall_molecule

unknown

Curated

← investigated for

Axitinibsmall_molecule

unknown

Curated

← investigated for

Atezolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Pexidartinibsmall_molecule

unknown

Curated

← investigated for

Oxaliplatinsmall_molecule

unknown

Curated

← investigated for

Leucovorinsmall_molecule

unknown

Curated

← investigated for

Irinotecansmall_molecule

unknown

Curated

← investigated for

Infigratinibsmall_molecule

unknown

Curated

← investigated for

Fluorouracilsmall_molecule

unknown

Curated

← investigated for

Everolimussmall_molecule

unknown

Curated

← investigated for

Buparlisibsmall_molecule

unknown

Curated

← investigated for

Binimetinibsmall_molecule

unknown

Curated

← investigated for

Alpelisibsmall_molecule

unknown

Curated

Gastrointestinal Stromal Tumor altered in cohorts of …ALTERED_INderived5 of 5
← altered in cohorts of	KIT 384 / 499 cases (77 %) · ssm · gist_msk_2022 · largest of 3 cohorts	—	—	Gastrointestinal Stromal Tumor	3	Observed	cbioportal	graph →
← altered in cohorts of	CSDE1 26 / 179 cases (15 %) · ssm · gist_msk_2025	—	—	Gastrointestinal Stromal Tumor	1	Observed	cbioportal	graph →
← altered in cohorts of	SETD2 21 / 183 cases (11 %) · ssm · gist_msk_2025	—	—	Gastrointestinal Stromal Tumor	1	Observed	cbioportal	graph →
← altered in cohorts of	TP53 20 / 183 cases (11 %) · ssm · gist_msk_2025	—	—	Gastrointestinal Stromal Tumor	1	Observed	cbioportal	graph →
← altered in cohorts of	PDGFRA 49 / 499 cases (9.8 %) · ssm · gist_msk_2022 · largest of 2 cohorts	—	—	Gastrointestinal Stromal Tumor	2	Observed	cbioportal	graph →

Gastrointestinal Stromal Tumor altered in cohorts of …ALTERED_INderived5 of 5

← altered in cohorts of

384 / 499 cases (77 %) · ssm · gist_msk_2022 · largest of 3 cohorts

—

Observed

← altered in cohorts of

CSDE1

26 / 179 cases (15 %) · ssm · gist_msk_2025

—

Observed

← altered in cohorts of

SETD2

21 / 183 cases (11 %) · ssm · gist_msk_2025

—

Observed

← altered in cohorts of

TP53

20 / 183 cases (11 %) · ssm · gist_msk_2025

—

Observed

← altered in cohorts of

49 / 499 cases (9.8 %) · ssm · gist_msk_2022 · largest of 2 cohorts

—

Observed

Gastrointestinal Stromal Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 65show all (up to 200)
→ investigated in trials for	Imatinib Mesylatesmall_molecule 34 trials (3 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	34	Observed	clinicaltrials	graph →
→ investigated in trials for	Imatinibsmall_molecule 28 trials (9 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	28	Observed	clinicaltrials	graph →
→ investigated in trials for	Sunitinibsmall_molecule 21 trials (5 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	21	Observed	clinicaltrials	graph →
→ investigated in trials for	Regorafenibsmall_molecule 15 trials (3 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Ripretinibsmall_molecule 13 trials (4 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Nilotinibsmall_molecule 12 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Avapritinibsmall_molecule 7 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal_antibody 5 trials (1 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Dasatinibsmall_molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Pazopanibsmall_molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Binimetinibsmall_molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal_antibody 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Pexidartinibsmall_molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Temozolomidesmall_molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal_antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Gastrointestinal Stromal Tumor	2	Observed	clinicaltrials	graph →

Gastrointestinal Stromal Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 65show all (up to 200)

→ investigated in trials for

Imatinib Mesylatesmall_molecule

34 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Imatinibsmall_molecule

28 trials (9 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sunitinibsmall_molecule

21 trials (5 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Regorafenibsmall_molecule

15 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ripretinibsmall_molecule

13 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nilotinibsmall_molecule

12 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Avapritinibsmall_molecule

7 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ipilimumabmonoclonal_antibody

5 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dasatinibsmall_molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pazopanibsmall_molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Binimetinibsmall_molecule

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal_antibody

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pexidartinibsmall_molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Temozolomidesmall_molecule

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal_antibody

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Gastrointestinal Stromal Tumor studied in …STUDIED_INderived10 of 341show all (up to 200)
→ studied in	NCT04924075Phase 2 · recruiting Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) · condition mapped CURATED_BROADER · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT06441331Phase 1 · recruiting Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors · condition mapped ALIAS · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07124000recruiting DESTINY-PANTUMOUR04 · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07585266Phase 3 · recruiting A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline) · condition mapped ALIAS · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07837271active not recruiting Development and External Validation of a Prognostic Model for DFS After Curative Resection of Duodenal GIST · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03602092completed Observational Registry Data on GIST Patients · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05152472Phase 2 · recruiting A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments · condition mapped CURATED_BROADER · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00265798Phase 2 · active not recruiting Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05493215Phase 2 · recruiting Imatinib TDM in GIST · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05867901suspended A Prospective Study on Predicting Recurrence Risk of Postoperative High-risk GISTs in NED State Based on MRD Detection Via Liquid Biopsy · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)	—	—	Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →

Gastrointestinal Stromal Tumor studied in …STUDIED_INderived10 of 341show all (up to 200)

→ studied in

NCT04924075Phase 2 · recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) · condition mapped CURATED_BROADER · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT06441331Phase 1 · recruiting

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors · condition mapped ALIAS · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT07124000recruiting

DESTINY-PANTUMOUR04 · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT07585266Phase 3 · recruiting

A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline) · condition mapped ALIAS · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT07837271active not recruiting

Development and External Validation of a Prognostic Model for DFS After Curative Resection of Duodenal GIST · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT03602092completed

Observational Registry Data on GIST Patients · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT05152472Phase 2 · recruiting

A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments · condition mapped CURATED_BROADER · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT00265798Phase 2 · active not recruiting

Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT05493215Phase 2 · recruiting

Imatinib TDM in GIST · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed

→ studied in

NCT05867901suspended

A Prospective Study on Predicting Recurrence Risk of Postoperative High-risk GISTs in NED State Based on MRD Detection Via Liquid Biopsy · condition mapped ONTOLOGY_EXACT · 341 trials mapped (72 active)

—

Observed