Gastric Neoplasm

Curated

← investigated for

Tislelizumabmonoclonal_antibody

unknown

Curated

← investigated for

Ramucirumabmonoclonal_antibody

unknown

Curated

← investigated for

Docetaxelsmall_molecule

unknown

Curated

← investigated for

Capecitabinesmall_molecule

unknown

Curated

← investigated for

Tegafursmall_molecule

unknown

Curated

← investigated for

Sugemalimabmonoclonal_antibody

unknown

Curated

← investigated for

Sintilimabmonoclonal_antibody

unknown

Curated

← investigated for

Serplulimabmonoclonal_antibody

unknown

Curated

← investigated for

Rilotumumabmonoclonal_antibody

unknown

Curated

← investigated for

Pertuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Pemetrexedsmall_molecule

unknown

Curated

← investigated for

Pembrolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Paclitaxelsmall_molecule

unknown

Curated

← investigated for

Oxaliplatinsmall_molecule

unknown

Curated

← investigated for

Onartuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Olaparibsmall_molecule

unknown

Curated

← investigated for

Nivolumabmonoclonal_antibody

unknown

Curated

← investigated for

Mitomycinsmall_molecule

unknown

Curated

← investigated for

Levoleucovorinsmall_molecule

unknown

Curated

← investigated for

Leucovorinsmall_molecule

unknown

Curated

← investigated for

Irinotecansmall_molecule

unknown

Curated

← investigated for

Ipilimumabmonoclonal_antibody

unknown

Curated

← investigated for

Fruquintinibsmall_molecule

unknown

Curated

← investigated for

Fluorouracilsmall_molecule

unknown

Curated

← investigated for

Everolimussmall_molecule

unknown

Curated

← investigated for

Etoposidesmall_molecule

unknown

Curated

← investigated for

Epirubicinsmall_molecule

unknown

Curated

← investigated for

Cisplatinsmall_molecule

unknown

Curated

← investigated for

Chlorambucilsmall_molecule

unknown

Curated

← investigated for

Cetuximabmonoclonal_antibody

unknown

Curated

← investigated for

Catumaxomabmonoclonal_antibody

unknown

Curated

← investigated for

Camrelizumabmonoclonal_antibody

unknown

Curated

← investigated for

Bevacizumabmonoclonal_antibody

unknown

Curated

← investigated for

Avelumabmonoclonal_antibody

unknown

Curated

← investigated for

Aspirinsmall_molecule

unknown

Curated

← investigated for

Zanidatamabmonoclonal_antibody

unknown

Curated

← investigated for

Vistusertibsmall_molecule

unknown

Curated

← investigated for

Vismodegibsmall_molecule

unknown

Curated

← investigated for

Vinfluninesmall_molecule

unknown

Curated

← investigated for

Vandetanibsmall_molecule

unknown

Curated

← investigated for

Tucatinibsmall_molecule

unknown

Curated

← investigated for

Tremelimumabmonoclonal_antibody

unknown

Curated

← investigated for

Trastuzumab Emtansineadc

unknown

Curated

← investigated for

Trastuzumab Deruxtecanadc

unknown

Curated

← investigated for

Trastuzumab Deruxtecanadc

unknown

Curated

← investigated for

Toripalimabmonoclonal_antibody

unknown

Curated

← investigated for

Sunitinibsmall_molecule

unknown

Curated

← investigated for

Sorafenib Tosylatesmall_molecule

unknown

Curated

← investigated for

Sorafenibsmall_molecule

unknown

Curated

← investigated for

Selumetinibsmall_molecule

unknown

Curated

← investigated for

Savolitinibsmall_molecule

unknown

Curated

← investigated for

Rucaparibsmall_molecule

unknown

Curated

← investigated for

Romidepsinother

unknown

Curated

← investigated for

Rituximabmonoclonal_antibody

unknown

Curated

← investigated for

Regorafenib Anhydroussmall_molecule

unknown

Curated

← investigated for

Regorafenibsmall_molecule

unknown

Curated

← investigated for

Raltitrexedsmall_molecule

unknown

Curated

← investigated for

Pyrotinibsmall_molecule

unknown

Curated

← investigated for

Pemigatinibsmall_molecule

unknown

Curated

← investigated for

Pegfilgrastimother

unknown

Curated

← investigated for

Pazopanibsmall_molecule

unknown

Curated

← investigated for

Panobinostatsmall_molecule

unknown

Curated

← investigated for

Panitumumabmonoclonal_antibody

unknown

Curated

← investigated for

Nintedanibsmall_molecule

unknown

Curated

← investigated for

Nimotuzumabmonoclonal_antibody

unknown

Curated

← investigated for

Luminespibsmall_molecule

unknown

Curated

← investigated for

Lenvatinibsmall_molecule

unknown

Curated

← investigated for

Lapatinibsmall_molecule

unknown

Curated

← investigated for

Ipatasertibsmall_molecule

unknown

Curated

← investigated for

Imatinib Mesylatesmall_molecule

unknown

Curated

← investigated for

Imatinibsmall_molecule

unknown

Curated

← investigated for

Hydroxyureasmall_molecule

unknown

Curated

← investigated for

Hydroxycarbamidesmall_molecule

unknown

Curated

← investigated for

Gefitinibsmall_molecule

unknown

Curated

← investigated for

Ganetespibsmall_molecule

unknown

Curated

← investigated for

Filgrastimother

unknown

Curated

← investigated for

Fexagratinibsmall_molecule

unknown

Curated

← investigated for

Durvalumabmonoclonal_antibody

unknown

Curated

← investigated for

Doxorubicinsmall_molecule

unknown

Curated

← investigated for

Dovitinibsmall_molecule

unknown

Curated

← investigated for

unknown

Curated

← investigated for

Dexamethasonesmall_molecule

unknown

Curated

← investigated for

Crizotinibsmall_molecule

unknown

Curated

← investigated for

Carboplatinsmall_molecule

unknown

Curated

← investigated for

Capivasertibsmall_molecule

unknown

Curated

← investigated for

Cabazitaxelsmall_molecule

unknown

Curated

← investigated for

Bortezomibsmall_molecule

unknown

Curated

← investigated for

Atezolizumabmonoclonal_antibody

unknown

Curated

← investigated for

Amivantamabmonoclonal_antibody

unknown

Curated

← investigated for

Adebrelimabmonoclonal_antibody

unknown

Curated

← investigated for

Adavosertibsmall_molecule

unknown

Curated

← investigated for

Vorinostatsmall_molecule

unknown

Curated

← investigated for

Veliparibsmall_molecule

unknown

Curated

← investigated for

Trametinibsmall_molecule

unknown

Curated

← investigated for

Tanespimycinsmall_molecule

unknown

Curated

← investigated for

Sacituzumab Govitecanadc

unknown

Curated

← investigated for

Poziotinibsmall_molecule

unknown

Curated

← investigated for

Niraparibsmall_molecule

unknown

Curated

← investigated for

Neratinibsmall_molecule

unknown

Curated

← investigated for

Mitoxantronesmall_molecule

unknown

Curated

← investigated for

Lurbinectedinsmall_molecule

unknown

Curated

← investigated for

Gemcitabinesmall_molecule

unknown

Curated

← investigated for

Derazantinibsmall_molecule

unknown

Curated

← investigated for

Crenolanibsmall_molecule

unknown

Curated

← investigated for

Cobimetinibsmall_molecule

unknown

Curated

← investigated for

Cemiplimabmonoclonal_antibody

unknown

Curated

← investigated for

Cediranibsmall_molecule

unknown

Curated

← investigated for

unknown

Curated

← investigated for

Axitinibsmall_molecule

unknown

Curated

← investigated for

Alpelisibsmall_molecule

unknown

Curated

← investigated for

Afatinibsmall_molecule

unknown

Curated

Gastric Neoplasm altered in cohorts of …ALTERED_INderived15 of 364show all (up to 200)
← altered in cohorts of	CSMD3 305 / 443 cases (69 %) · ssm · TCGA-STAD · largest of 4 cohorts	—	—	Gastric Adenocarcinoma	4	Observed	gdc	graph →
← altered in cohorts of	FER1L6 299 / 443 cases (67 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	MYC 296 / 443 cases (67 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	POU5F1B 294 / 443 cases (66 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	ASAP1 293 / 443 cases (66 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	DDX27 292 / 443 cases (66 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	COL14A1 290 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	ZNF831 290 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	GSDMC 289 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	NFATC2 289 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	ANXA13 288 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	KLHL38 288 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	WASHC5 288 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	ATAD2 287 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →
← altered in cohorts of	EXT1 287 / 443 cases (65 %) · ssm · TCGA-STAD	—	—	Gastric Adenocarcinoma	1	Observed	gdc	graph →

Gastric Neoplasm altered in cohorts of …ALTERED_INderived15 of 364show all (up to 200)

← altered in cohorts of

CSMD3

305 / 443 cases (69 %) · ssm · TCGA-STAD · largest of 4 cohorts

—

Observed

← altered in cohorts of

FER1L6

299 / 443 cases (67 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

MYC

296 / 443 cases (67 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

POU5F1B

294 / 443 cases (66 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

ASAP1

293 / 443 cases (66 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

DDX27

292 / 443 cases (66 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

COL14A1

290 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

ZNF831

290 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

GSDMC

289 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

NFATC2

289 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

ANXA13

288 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

KLHL38

288 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

WASHC5

288 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

ATAD2

287 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

← altered in cohorts of

EXT1

287 / 443 cases (65 %) · ssm · TCGA-STAD

—

Observed

Gastric Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 175show all (up to 200)
→ investigated in trials for	Oxaliplatinsmall_molecule 229 trials (76 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	229	Observed	clinicaltrials	graph →
→ investigated in trials for	Capecitabinesmall_molecule 172 trials (49 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	172	Observed	clinicaltrials	graph →
→ investigated in trials for	Fluorouracilsmall_molecule 151 trials (46 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	151	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall_molecule 129 trials (19 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	129	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall_molecule 107 trials (21 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	107	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall_molecule 107 trials (36 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	107	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal_antibody 100 trials (37 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	100	Observed	clinicaltrials	graph →
→ investigated in trials for	Irinotecansmall_molecule 85 trials (17 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	85	Observed	clinicaltrials	graph →
→ investigated in trials for	Leucovorinsmall_molecule 77 trials (23 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	77	Observed	clinicaltrials	graph →
→ investigated in trials for	Trastuzumabmonoclonal_antibody 73 trials (25 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	73	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal_antibody 54 trials (26 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	54	Observed	clinicaltrials	graph →
→ investigated in trials for	Ramucirumabmonoclonal_antibody 43 trials (13 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	43	Observed	clinicaltrials	graph →
→ investigated in trials for	Chemotherapy 32 trials (15 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	32	Observed	clinicaltrials	graph →
→ investigated in trials for	Sintilimabmonoclonal_antibody 29 trials (14 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	29	Observed	clinicaltrials	graph →
→ investigated in trials for	Tislelizumabmonoclonal_antibody 28 trials (19 active) · roll-up of the cancer and its descendants	—	—	Gastric Neoplasm	28	Observed	clinicaltrials	graph →

Gastric Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 175show all (up to 200)

→ investigated in trials for

Oxaliplatinsmall_molecule

229 trials (76 active) · roll-up of the cancer and its descendants

—

229

Observed

→ investigated in trials for

Capecitabinesmall_molecule

172 trials (49 active) · roll-up of the cancer and its descendants

—

172

Observed

→ investigated in trials for

Fluorouracilsmall_molecule

151 trials (46 active) · roll-up of the cancer and its descendants

—

151

Observed

→ investigated in trials for

Cisplatinsmall_molecule

129 trials (19 active) · roll-up of the cancer and its descendants

—

129

Observed

→ investigated in trials for

Docetaxelsmall_molecule

107 trials (21 active) · roll-up of the cancer and its descendants

—

107

Observed

→ investigated in trials for

Paclitaxelsmall_molecule

107 trials (36 active) · roll-up of the cancer and its descendants

—

107

Observed

→ investigated in trials for

Pembrolizumabmonoclonal_antibody

100 trials (37 active) · roll-up of the cancer and its descendants

—

100

Observed

→ investigated in trials for

Irinotecansmall_molecule

85 trials (17 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Leucovorinsmall_molecule

77 trials (23 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Trastuzumabmonoclonal_antibody

73 trials (25 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal_antibody

54 trials (26 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ramucirumabmonoclonal_antibody

43 trials (13 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Chemotherapy

32 trials (15 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sintilimabmonoclonal_antibody

29 trials (14 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Tislelizumabmonoclonal_antibody

28 trials (19 active) · roll-up of the cancer and its descendants

—

Observed

Gastric Neoplasm studied in …STUDIED_INderived10 of 3,258show all (up to 200)
→ studied in	NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 3,258 trials mapped (951 active)	—	—	Gastric Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04396821Phase 1/Phase 2 · active not recruiting A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)	—	—	Malignant Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05891171Phase 1 · active not recruiting Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)	—	—	Malignant Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06093425Phase 3 · not yet recruiting Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma · condition mapped PROBABILISTIC · 3,258 trials mapped (951 active)	—	—	Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06203600Phase 2/Phase 3 · recruiting Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)	—	—	Gastric Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07529808Phase 1/Phase 2 · recruiting Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)	—	—	Malignant Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07578571Phase 1 · recruiting A Phase 1 Study of IM-1617 in Participants With Advanced Cancer · condition mapped CURATED_EXACT · 3,258 trials mapped (951 active)	—	—	Malignant Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07583810Phase 2 · recruiting Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma · condition mapped ONTOLOGY_EXACT · 3,258 trials mapped (951 active)	—	—	Gastric Mucosa-Associated Lymphoid Tissue Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07700979Phase 3 · recruiting Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma · condition mapped ALIAS · 3,258 trials mapped (951 active)	—	—	Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT03030404completed Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer · condition mapped ALIAS · 3,258 trials mapped (951 active)	—	—	Gastric Neoplasm	1	Observed	clinicaltrials	graph →

Gastric Neoplasm studied in …STUDIED_INderived10 of 3,258show all (up to 200)

→ studied in

NCT02465060Phase 2 · active not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 3,258 trials mapped (951 active)

—

Gastric Carcinoma

Observed

→ studied in

NCT04396821Phase 1/Phase 2 · active not recruiting

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT05891171Phase 1 · active not recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT06093425Phase 3 · not yet recruiting

Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma · condition mapped PROBABILISTIC · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT06203600Phase 2/Phase 3 · recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT07529808Phase 1/Phase 2 · recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma · condition mapped CURATED_BROADER · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT07578571Phase 1 · recruiting

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer · condition mapped CURATED_EXACT · 3,258 trials mapped (951 active)

—

Observed

Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

→ studied in

NCT07583810Phase 2 · recruiting

Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma · condition mapped ONTOLOGY_EXACT · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT07700979Phase 3 · recruiting

Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma · condition mapped ALIAS · 3,258 trials mapped (951 active)

—

Observed

→ studied in

NCT03030404completed

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer · condition mapped ALIAS · 3,258 trials mapped (951 active)

—

Observed