NFATC2 — gene · CancerIndex

Curated evidence

Clinical evidence (6)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–6 of 6 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
NFATC2 Fusion3
(diagnostic)	Round Cell Sarcoma with EWSR1-non-ETS Fusion	Diagnostic	B	Supports Positive	3	accepted	EID11604 This analysis of small round cell tumors of the bone identified 3 with EWSR1::NFATC2 fusions and 1 with a FUS::NFATC2 fusion. The authors extended their review to an additional 45 cases in the litera… (full text at CIViC) PMID 31078563 · Diaz-Perez et al., 2019 · Open in CIViC	civic
〃	Round Cell Sarcoma with EWSR1-non-ETS Fusion	Diagnostic	C	Supports Positive	3	accepted	EID12590 A small case series examined molecular features along with clinicopathologic and immunohistochemical characteristics of sarcomas with EWSR1::NFATC2 gene fusions. The study included 6 cases (5 males an… (full text at CIViC) PMID 30994538 · Wang et al., 2019 ·

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

gdcObserved5 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Colon Adenocarcinoma TCGA-COAD	Colon Adenocarcinoma	Ssm

Literature

25 per page, newest first.

pubmedPublishedShowing 1–5 of 5 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.