Publication
The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology.
Authors not recorded
Clin Cancer Res2009PMID 19318479stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Data not yet available
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerRound Cell Sarcoma with EWSR1-non-ETS Fusioncivic_curation1.00
- geneNFATC2civic_curation1.00
- variantNFATC2 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 19318479
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NFATC2 Fusion1 | ||||||||
| (diagnostic) | Round Cell Sarcoma with EWSR1-non-ETS Fusion | Diagnostic | C | Supports Positive | 3 | accepted | EID12591This landmark study represents the first description of the EWSR1::NFATC2 fusion in Ewing-like sarcomas, leading to the establishment of 'round cell sarcoma with EWSR1-non-ETS fusions' as a new diseas… (full text at CIViC) PMID 19318479 · Szuhai et al., 2009 · Open in CIViC | civic |