Gene

GREB1

growth regulating estrogen receptor binding 1

Explore in graph →CI-GENE-00003586HGNC:24885 ENSG00000196208 NCBI 9687 Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CITED2 Fusion + NCOA3 Fusion + ESR1 Fusion + NCOA2 Fusion + GREB1 FusionNCOA3 NCOA2 CITED2 ESR1 GREB11
(prognostic)	Malignant Uterine NeoplasmALIAS	Prognostic	C	Supports Poor Outcome	1	submitted	EID12707 In a retrospective UTROSCT cohort (n = 17, follow-up n = 13), 3 patients (23.1%) carrying GREB1::NCOA2, ESR1::NCOA3 or ESR1::CITED2 fusions developed pelvic, abdominal or pulmonary recurrence, with re… (full text at CIViC) PMID 38000680 · Qijun et al., 2024 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (16)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved16 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Colorectal Adenocarcinoma (Genentech, Nature 2012) coadread_genentech	Colorectal Adenocarcinoma	Ssm	9	72

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.