Gene
COL4A2
collagen type IV alpha 2 chain
Explore in graph →CI-GENE-00041845HGNC:2203 ENSG00000134871 NCBI 1284 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (19)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36577525
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Myoepithelial Carcinomas of Soft Tissue (WCM, CSH Molecular Case Studies 2022) stmyec_wcm_2022 | Malignant Myoepithelioma | Ssm | 5 | 12 | 41.7% | 2 | cbioportal |
| Cutaneous Squamous Cell Carcinoma (UCSF, NPJ Genom Med 2021) cscc_ucsf_2021 | Skin Squamous Cell Carcinoma | Ssm | 17 | 83 | 20.5% | 179 | cbioportal |
| Melanoma (MSK, Cell 2017) - iAtlas Harmonized mel_iatlas_riaz_nivolumab_2017 | Melanoma | Ssm | 9 | 73 | 12.3% | 95 | cbioportal |
| Colorectal Cancer Radiation (MSK, 2024) rectal_radiation_msk_2024 | Rectal Adenocarcinoma | Ssm | 2 | 17 | 11.8% | 179 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.