Variant · Snv
COL4A2 NM_001846.4(COL4A2):c.1011G>A (p.Lys337=)
CI-VAR-00126585Explore in graph →p.Lys337=NM_001846.4:c.1011G>AClinVar 776812 rs147765396
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 776812 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | COL4A2-related disorder; Uterine corpus endometrial carcinoma; Malignant tumor of urinary bladder; Hepatocellular carcinoma; Malignant tumor of esophagus; Adrenocortical carcinoma, hereditary; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Lung cancer; Familial cancer of breast; Clear cell carcinoma of kidney; Uterine carcinosarcoma; Cervical cancer | germline | 8 | Jan 18, 2026 | clinvar |