Variant · Snv
COL4A2 NM_001846.4(COL4A2):c.3455-5C>G
CI-VAR-00052338Explore in graph →NM_001846.4:c.3455-5C>GClinVar 311163 rs2296849
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 311163 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Brain small vessel disease 2A, autosomal dominant; Ovarian serous cystadenocarcinoma; Thymoma; Uterine carcinosarcoma; Cholangiocarcinoma; Clear cell carcinoma of kidney; Colon adenocarcinoma; Gastric cancer; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Lung cancer | germline | 7 | Feb 03, 2026 | clinvar |